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Original Article

Effects of the Anti-Gastric Secretory Drugs IT-066 and Omeprazole on Mitogenic Activities in the Gastric Juice of the Rat

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Pages 111-117 | Received 09 Jan 1995, Accepted 06 Jun 1995, Published online: 08 Jul 2009

References

  • Murphy RA, Pantazis NJ, Papastavros M. Epidermal growth factor and nerve growth factor in mouse saliva: a comparative study. Dev Biol 1979; 71: 356–70
  • Humphreys BM, Macauley SP, Chegini N, Setten G, Purushotham K, Stewart C. Characterization of the synthesis and secretion of transforming growth factor-alpha from salivary glands and saliva. Endocrinology 1994; 134: 963–70
  • Yeh YC, Guh JY, Yeh J, Yeh HW. Transforming growth factor type alpha in normal human adult saliva. Mol Cell Endocrinol 1989; 67: 247–55
  • Costigan DC, Guyda HJ, Posner BI. Free insulin-like growth factor I (IGF-I) and IGF-II in human saliva. J Clin Endocrinol Metab 1988; 66: 1014–8
  • Gregory H, Walsh S, Hopkins CR. The identification of urogastrone in serum, saliva, and gastric juice. Gastroenterology 1979; 77: 313–8
  • Konturek SJ, Brzozowski T, Piastucki I, Dembinski A, Radecki T, Dembinska KA. Role of mucosal prostaglandins and DNA synthesis in gastric cytoprotection by luminal epidermal growth factor. Gut 1981; 22: 927–32
  • Kirkegaard P, Olsen PS, Poulsen SS, Nexo E. Epidermal growth factor inhibits cysteamine-induced duodenal ulcers. Gastroenterology 1983; 85: 1277–83
  • Olsen PS, Poulsen SS, Kirkegaard P, Nexo E. Role of submandibular saliva and epidermal growth factor in gastric cytoprotection. Gastroenterology 1984; 87: 103–8
  • Itoh M, Imai S, Joh T, Kawai T, Katsumi K, Yokochi K. Protection of gastric mucosa against ethanol-induced injury by intragastric bolus administration of epidermal growth factor combined with hydroxypropylcellulose. J Clin Gastroenterol 1992; 14: S127–30, Suppl 1
  • Joh T, Itoh M, Katsumi K, Yokoyama T, Miyamoto T, Imai S. Immunoreactive epidermal growth factor in mouse digestive organs. Use of a sensitive enzyme immunoassay. Acta Endocrinol (Copenh) 1987; 115: 203–10
  • Joh T, Itoh M, Yasue N, Miyamoto T, Iwai A, Matsusako K. A sensitive enzyme immunoassay system of rat epidermal growth factor in biological fluids and tissue extracts. Acta Endocrinol (Copenh) 1989; 120: 616–23
  • Barka T. Biologically active polypeptide in submandibular glands. J Histochem Cytochem 1980; 28: 836–59
  • Murphy RA, Watson AY, Metz J, Forssmann WG. The mouse submandibular gland: an exocrine organ for growth factors. J Histochem Cytochem 1980; 28: 890–902
  • Hutson JM, Niall M, Evans D, Fowler R. Effect of salivary glands on wound contraction in mice. Nature 1979; 279: 793–5
  • Li AKC, Koroly MJ, Schattenkerk ME, Malt RA, Young M. Nerve growth factor: acceleration of the rate of wound healing in mice. Proc Natl Acad Sci USA 1980; 77: 4379–81
  • Noguchi S, Ohba Y, Oka T. Effect of salivary epidermal growth factor on wound healing of tongue in mice. Am J Physiol 1991; 260: E620–5
  • Carpenter G, Cohen S. Epidermal growth factor. Ann Rev Biochem 1979; 48: 193–216
  • Konturek JW, Bielanski W, Konturek SJ, Bogdal J, Oleksy J. Distribution and release of epidermal growth factor in man. Gut 1989; 30: 1194–200
  • Konturek SJ, Dembinski A, Warzecha Z, Brzozowski T, Gregory H. Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats. Gastroenterology 1988; 94: 1300–7
  • Olsen PS, Poulsen SS, Therkelsen K, Nexo E. Oral administration of synthetic human urogastrone promote healing of chronic duodenal ulcers in rats. Gastroenterology 1986; 90: 911–7
  • Britton JR, George NC, Koldovsky O. Luminal hydrolysis of recombinant human epidermal growth factor in the rat gastrointestinal tract: segmental and developmental differences. Life Sci 1988; 43: 1339–47
  • Britton JR, George NC, Udall JN, Koldovsky O. Minimal hydrolysis of epidermal growth factor by gastric fluid of preterm infants. Gut 1989; 30: 327–32
  • Schaudies RP, Grimes J, Davis D, Rao RK, Koldovsky O. EGF content in the gastrointestinal tract of rats: effect of age and fasting/feeding. Am J Physiol 1989; 256: G856–61
  • Hock RA, Hollenberg MD. Characterization of the receptor for epidermal growth factor-urogastrone in human placenta membranes. J Biol Chem 1980; 255: 10731–6
  • Playford RJ, Woodman AC, Clark P, Watanapa P, Vesey D, Deprez PH. Effect of luminal growth factor preservation on intestinal growth. Lancet 1993; 341: 843–8
  • Playford RJ, Marchbank T, Calnan DP, Calam J, Royston P, Batten JJ. Epidermal growth factor is digested to smaller less active forms in acidic gastric juice. Gastroenterology 1995; 108: 92–101
  • Folkmann J, Szabo S, Stovroff M, Mcneil P, Li W, Shing Y. Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg 1991; 214: 414–27
  • Brzozowski T, Majka J, Konturek SJ. Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. Digestion 1992; 51: 27–36
  • Wright NA, Pike C, Elia G. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature 1990; 343: 82–5
  • Konturek SJ. Role of growth factors in gastroduodenal protection and healing of peptic ulcers. Gastroenterol Clin North Am 1990; 19: 41–65

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