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Original Article

The X-Ray Contrast Medium Iodixanol Detects Increased Colonic Permeability Equally Well as 51Cr-labeled Ethylenediaminetetraacetic Acid in Experimental Colitis of Rats

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Pages 140-146 | Received 05 Jan 1995, Accepted 08 Jun 1995, Published online: 08 Jul 2009

References

  • Hollander D. Crohn's disease—a permeability disorder of the tight junction. Gut 1988; 29: 1621–4
  • Almer S, Franzen L, Olaison G, Smedh K, Strom M. Increased absorption of polyethylene glycol 600 deposited in the colon in active ulcerative colitis. Gut 1993; 34: 509–13
  • Bjarnason I, Peters TJ, Veal N. A persistent defect in intestinal permeability in coeliac disease demonstrated by a 51Cr-labelled EDTA absorption test. Lancet 1983; 2: 323–5
  • Bjarnason I, Peters TJ. Intestinal permeability non-steroidal anti-inflammatory drug enteropathy and inflammatory bowel disease: an overview. Gut 1989; 30: 22–8
  • Coltart RS, Howard GC, Wraight EP, Bleehen NM. The effect of hyperthermia and radiation on small bowel permeability using 51Cr EDTA and 14C mannitol in man. Int J Hyperthermia 1988; 4: 467–77
  • Jackson PG, Lessof MH, Baker RWR, Ferret J, MacDonald DM. Intestinal permeability in patients with eczema and food allergy. Lancet 1981; 2: 1285–6
  • Juby LD, Rothwell J, Axon AT. Lactulose/mannitol test: an ideal screen for celiac disease. Gastroenterology 1989; 96: 79–85
  • Oeman H, Aakerblom E, Richter W, Johansson SGO. Chemical and physiological properties of polysucrose a new marker of intestinal permeability to macromolecules. Int Arch Allerg Immunol 1992; 98: 220–6
  • Ukabam SO, Clamp JR, Cooper BT. Abnormal intestinal permeability to sugars in patients with Crohn's disease of the terminal ileum and colon. Digestion 1983; 17: 70–4
  • Nossen JO, Andrew E, Aakhus T, Berg KJ, Jorgensen NP. Iodixanol. A new isotonic x-ray contrast medium. Tidsskr Nor Laegeforen 1991; 111: 1108–11
  • Stordahl A, Laerum F. Water-soluble contrast media compared with barium in enteric follow-through. Urinary excretion and radiographic efficacy in rats with intestinal ischemia. Invest Radiol 1988; 23: 471–7
  • Laerum F, Stordahl A, Solheim KE, Haugstvedt JR, Roald HE, Skinningsrud K. Intestinal follow-through examinations with iohexol and iopentol. Permeability alterations and efficacy in patients with small bowel obstruction. Invest Radiol 1991; 26: S177–S181
  • Halme L, Edgren J, Von SK, Linden H. Increased urinary excretion of iohexol after enteral administration in patients with ileal Crohn's disease. A new test for disease activity. Acta Radiol 1993; 34: 237–41
  • Krugliak P, Hollander D, Schlaepfer CC, Katz KD, Dadufalza VD, Ma TY. Polyethylene glycol 400 penetration of the colonic epithelial barrier of the rat. Gastroenterology 1990; 99: 1001–7
  • Pressman JH, Hofmann AF, Witztum KF, Gertler SL, Steinbach JH, Stokes K. Limitations of indirect methods of estimating small bowel transit in man. Dig Dis Sci 1987; 32: 689–99
  • Bjarnason I, O'Morain C, Levi AJ, Peters TJ. Absorption of 51chromium-labelled ethylenediaminetetracetate in inflammatory bowel disease. Gastroenterology 1983; 85: 318–22
  • Wyatt J, Vogelsang H, Hubl W, Waldhoer T, Lochs H. Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet 1993; 341: 1437–9
  • Teahon K, Smethurst P, Pearson M, Levi AJ, Bjarnason I. The effect of elemental diet on intestinal permeability and inflammation in Crohn's disease. Gastroenterology 1991; 101: 84–9
  • Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989; 96: 795–803
  • Edelson J, Palace G, Park G. High performance liquid chromatographic determination of iohexol in plasma urine and feces. J Chromatogr 1983; 274: 428–33
  • Hollander D, Ricketts D, Boyd CAR. Importance of ‘probe’ molecular geometry in determining intestinal permeability. Can J Gastroenterol 1988; 2: 35, A–38A.
  • Jakobsen JA, Lundby B, Kristoffersen DT, Borch KW, Hald JK, Berg KJ. Evaluation of renal function with delayed CT after injection of nonionic monomeric and dimeric contrast media in healthy volunteers. Radiology 1992; 182: 419–24
  • Svaland MG, Haider T, Langseth MK, Andrew E, Hals PA. Human pharmacokinetics of iodixanol. Invest Radiol 1992; 27: 130–3
  • Dixon WJ, Brown MB, Engelman L, Jennrich RI. BMDP statistical software. University of California Press, Berkeley 1990
  • Andersen R, Laerum F, Bay D, Aas K, Halstensen TS, Stordahl A. Experimental colonic inflammation and ulceration. Permeation of a water-soluble contrast medium as a measure of ‘disease’ activity. Scand J Gastroenterol 1992; 27: 757–63
  • Stordahl A. Urinary excretion of iohexol after intestinal administration in rats with bowel ischaemia. The effects of mesenteric arterial and/or venous occlusion. Acta Radiol 1989; 30: 87–92
  • Andersen R, Stordahl A, Høyseth H, Koppers R, Tverdal Aa, Aase S. Increased intestinal permeability for the isosmolar contrast medium iodixanol during small-bowel ischaemia in rats. Scand J Gastroenterol 1995; 30: 000–000
  • Laerum F, Fausa O, Ferstad S, Nordøy I, Solheim KE, Stordahl A. A dimeric, non-ionic contrast medium (iotrolan) as intestinal permeation marker in active Crohn's disease. Gut 1994; 35: A 123
  • Walker WA, Isselbacher KJ. Uptake and transport of macro-molecules by the intestine: possible role in clinical disorders. Gastroenterology 1974; 67: 531–50
  • Andre F, Andre C, Emery Y, Forichon J, Descos L, Minaire Y. Assessment of the lactulose-mannitol test in Crohn's disease. Gut 1988; 29: 511–5
  • Madara JL. Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier. Am J Pathol 1990; 137: 1273–81
  • Deitch EH, Winterton J, Li M, Berg R. The gut as a portal of entry for bacteremia. Ann Surg 1987; 205: 681–92
  • Moss AA, Kaufman L, Nelson JA. Fluorescent excitation analysis: A simplified method of iodine determination in vitro. Invest Radiol 1972; 7: 335–8
  • Grønberg T, Sjøberg S, Almén T, Golman K, Mattsson S. Noninvasive estimation of kidney function by X-ray fluorescence analysis. Elimination rate and clearance of contrast media injected for urography in man. Invest Radiol 1983; 18: 445–52

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