References
- Forstner G. Signal transduction, packaging and secretion of mucins. Annu Rev Physiol 1995; 57: 585–605
- Forstner J F, Forstner G. Gastrointestinal mucus. Physiology of the gastrointestinal tract3rd ed., L R Johnson. Raven Press, New York 1994; 1225–83
- Karlsson K ‐A, Angström J, Teneberg S. Characteristics of the recognition of host cell carbohydrates by viruses and bacteria. Molecular pathogenesis of gastrointestinal infections, T Wadström, et al. Plenum Press, New York 1991; 9–21
- Lesher B, Walburg H E, Sacher G A. Generation cycle in the duodenal crypts of germ‐free and conventional mice. Nature 1964; 202: 884–6
- Enss M ‐L, Grosse‐Siestrup H, Schmidt‐Wittig U, Gärtner K. Changes in colonic mucins of germfree rats in response to the introduction of a ‘normal’ rat microflora. J Exp Anim Sci 1992; 34: 110–9
- Hoskins L C, Augustines M C, McKee W B, Boulding E T, Kriaris M, Niedermeyer G. Mucin degradation in human colon ecosystem. Isolation and properties of strains, that degrade ABH blood group antigens and oligosaccharides from mucus glycoproteins. J Clin Invest 1985; 75: 944–53
- Wold J K, Midtvedt T, Jeanloz R W. Intestinal glycoproteins of germ‐free rats. III. Characterization of a water‐soluble glycoprotein fraction. Acta Chem Scand 1974; B28: 277–84
- Heneghan J B. Physiology of the alimentary tract. The germfree animal in biomedical research, M E Coates, B E Gustafsson. Laboratory Animals Ltd., London 1984; 169–92
- Abrams G D, Bauer H, Spritz H. Influence of the normal flora on mucosa morphology and cellular renewal in the ileum. A comparison of germ‐free and conventional mice. Lab Invest 1963; 12: 356–64
- Hill R R, Cowley H M. Alteration in colonic crypt architecture and mucin production following polyassociation of germfree mice with autochtonous crypt‐inhabiting bacteria. Microecol Ther 1981; 19: 71–8
- Enss M ‐L, Schmidt‐Witting U, Höner K, Kownatzky R, Gärtner K. Mechanical challenge causes alterations of rat colonic mucosa and released mucins. J Exp Anim Sci 1994; 36: 128–40
- Szentkuti L, Riedesel H, Enss M ‐L, Gärtner K, v Engelhardt W. Preepithelial mucus layer in the colon of conventional and germfree rats. Histochem J 1990; 22: 491–7
- Diagnostic microbiology for laboratory animals. GV‐SOLAS, I Kunstyr. Gustav Fischer, Stuttgart 1992; Vol 11
- Kamphues J. Lipopolysaccharide in Futtermitteln—mögliche Bedeutung, Bestimmung und Gehalte. Ubers Tiererng 1986; 14: 131–6
- Allen A, Carrol N JK. Adherent and soluble mucus in the stomach and duodenum. Dig Dis Sci 1986; 30: 55S–62S
- Enss M ‐L, Schmidt‐Wittig U, Heim H ‐K, Sewing K ‐F. Prostaglandin E2 alters terminal glycosylation of high molecular weight glycoproteins, released by pig gastric mucous cells in vitro. Prostagland Leukotr Essent Fatty Acids 1995; 52: 333–40
- Laux D C, McSweegan E F, Cohen P S. Adhesion of enterotoxigenic E. coli to immobulized intestinal mucosal preparations: a model for adhesion to mucosal surface components. J Microbiol Methods 1984; 2: 27–39
- Gordon H A, Bruckner B S. Anomalous lower bowel function and related phenomena in germfree animals. The germfree animal in biomedical research, M E Coates, B E Gustafsson. Laboratory Animals Ltd., London 1984; 193–213
- Kyoi T, Ueda F, Kimura K, Yamamota M, Kataoke K. Development of gap junctions between gastric surface mucous cells during cell maturation in rats. Gastroenterology 1992; 103: 1930–5
- Ciancio M J, Vitiritti L, Dhar A, Chang E B. Endotoxin‐induced alterations in rat colonic water and electrolyte transport. Gastroentrology 1992; 103: 1437–43
- Deitch E A, Ma W J, Ma L, Berg R, Specian R D. Endotoxininduced bacterial translocation: a study of mechanisms. Surgery 1989; 106: 292–300
- Defaux J P, Thornier F, Baroggi N, Etienne A, Braquet P. Involvement of platelet‐activating factor (PAF) in endotoxin‐ or ischaemia‐induced intestinal hyperpermeability in the rat. J Lipid Mediators 1993; 7: 11–21
- Rietschel E T, Galanos C, Luederitz O, Westphal O. Chemical structure, physiological function and biological activity of lipopolysaccharides and their lipid A component. Immunopharmacology and the regulation of leukocyte function, R D Webb. Marcel Dekker, New York 1982; 183–229
- Loppnow H, Brade H, Rietschel E T, Flad H D. Induction of cytokines in mononuclear and vascular cells by endotoxin and other bacterial products. Methodes in enzymology. Vol. 236, Bacterial pathogenesis, V L Clark, P M Bavoil. Academic Press Inc, San Diego 1994; 3–10
- Dinarello C A. The biological properties of interleukin‐1. Eur Cytokine Netw 1994; 5: 517–31
- Cohan V L, Scott A L, Dinarello C A, Prendergast R A. Interleukin‐1 is a mucus secretagogue. Cell Immunol 1991; 136: 425–34
- Han V, Resau J, Prendergast R, Scott A, Levy D A. Interleukin‐1 induces mucus secretion from mouse intestinal explants. Int Arch Allergy Appl Immunol 1987; 82: 364–5
- Mester M D, Tompkins R G, Gelfand J A, Dinarello C A, Burke J F, Clark B D. Intestinal production of Interleukin‐1α during endotoxemia in the mouse. J Surg Res 1993; 54: 584–91
- Sperber K, Ogata S, Sylvester C, Aisenberg J, Chen A, Mayer L, et al. A novel human macrophage‐derived mucin secretagogue: implication for the pathogenesis of inflammatory bowel disease. Gastroenterology 1993; 104: 1302–9
- Weldon M J, Maxwell J D. Lymphocyte and macrophage interleukin receptors in inflammatory bowel disease: a more selective target for therapy?. Gut 1994; 35: 867–71
- Rogers D F. Airway goblet cells: responsive and adaptable frontline defenders. Eur Resp J 1994; 7: 1690–706
- Houdret N, Ramphal R, Scharfman A, Perini J M, Filliat J M, Lamblin G, et al. Evidence for the in vitro degradation of human respiratory mucins during Pseudomonas aeruginosa infection. Biochem Biophys Acta 1989; 992: 96–105
- Tabak L A. In defense of the oral cavity: structure, biosynthesis and function of salivary mucins. Annu Rev Physiol 1995; 57: 547–64
- Kosmala M, Carter S, Konturek S J, Slomiany A, Slomiany B L. Mucus glycoprotein secretion by duodenal mucosa in response to luminal arachidonic acid. Biochim Biophys Acta 1986; 884: 419–28
- Rhodes J M, Black R R, Savage A. Altered lectin‐binding by colonic epithelial glycoconjugates in ulcerative colitis and Crohn's disease. Dig Dis Sci 1988; 33: 1359–63
- Ishikawa N, Horii Y, Nawa Y. Immun‐mediated alteration of the terminal sugars of goblet cell mucins in the small intestine of Nippostrongylus brasiliensis‐infected rats. Immunology 1993; 78: 303–7
- Strous G J, Dekker J. Mucin‐type glycoproteins. Crit Rev Biochem Mol Biol 1992; 27: 57–92
- Mack D R, Gaginella T S, Sherman P M. Effect of colonic inflammation on mucin inhibition of Escherichia coli RDEC‐1 binding in vitro. Gastroentrology 1992; 102: 1199–211
- Carlstedt I, Sheehan J K, Corfield A P, Gallagher J T. Mucous glycoproteins: a gel of a problem. Essays Biochem 1985; 20: 40–77
- Wadlowski E A, Laux D C, Cohen P S. Colonization of the streptomycin‐treated mouse large intestine by a human fecal Escherichia coli strain: role of growth in mucus. Infect Immun 1988; 56: 1030–5
- Wanke C A, Cronan S, Goss C, Chadee K, Guerrant R L. Characterization of binding of Escherichia coli strains which are enteropathogens to small‐bowel mucins. Infect Immun 1990; 58: 794–800
- Tsipori S, Montanaro J, Robins‐Browne R M, Vial P, Gibson R, Levine M M. Studies of enteroaggregative Escherichia coli in the gnotobiotic piglet gastritis model. Infect Immun 1992; 60: 5302–6
- Alverdy J C, Facs M D, Aoys E. The effect of dexametasone and endotoxin administration on bilary IgA and bacterial adherence. J Surg Res 1992; 53: 450–4
- Ruggieri M R, Balagani R K, Rajter J J, Hanno P M. Characterization of bovine gall bladder mucin fractions that inhibit Escherichia coli adherence to the mucin deficient rabbit bladder. J Urol 1992; 148: 173–8
- Venegas M F, Navas E L, Gaffney R A, Duncan J L, Anderson B E, Schaeffer A J. Binding of type 1‐piliated Escherichia coli to vaginal mucus. Infect Immun 1995; 63: 416–22
- Mack D R, Sherman P M. Mucin isolated from rabbit colon inhibits in vitro binding of Escherichia coli RDEC‐1. Infect Immun 1991; 59: 1015–23