20
Views
16
CrossRef citations to date
0
Altmetric
Original Article

Experimental Models of Acute Pancreatitis and their Relevance to Human Disease

Pages 6-9 | Published online: 08 Jul 2009

References

  • Lampel M, Kern H. Acute interstitial pancreatitis in the rat induced by excessive doses of pancreatic secretagogue. Virchows Arch A Pathol Anat Histopathol 1977; 373: 97–117
  • Lombardi B, Estes L W, Longnecker D S. Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol 1975; 79: 465–80
  • Steer M L, Meldolesi J. The cell biology of experimental pancreatitis. N Engl J Med 1987; 316: 144–50
  • Kloppel G, Dreyer T, Willemer S, Kern H F, Adler G. Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells. Virchows Arch A Pathol Anat Histopathol 1986; 409: 791–803
  • Willemer S, Adler G. Histochemical and ultrastructural characterization of tubular complexes in human acute pancreatitis. Dig Dis Sci 1989; 34: 46–55
  • Steinberg W M, Schlesselman S E. Treatment of acute pancreatitis. Comparison of animal and human studies. Gastroenterology 1987; 93: 1420–7
  • Fernandez-del Castillo C, Schmidt J, Warshaw A L, Rattner D W. Interstitial protease activation is the central event in progression to necrotizing pancreatitis. Surgery 1994; 116: 497–504
  • Schmidt J. A better model of acute pancreatitis for evaluating therapy. Annal Surg 1992; 215: 44–56
  • Harvey M H, Wedgwood K R, Austin J A, Reber H A. Pancreatic duct pressure duct permeability and acute pancreatitis. Br J Surg 1989; 76: 859–62
  • Schmidt J, Fernandez-del Castillo C, Rattner D W, Lewandrowski K, Messmer K, Warshaw A L. Hyperoncotic ultrahigh molecular weight dextran solutions reduce trypsinogen activation, prevent acinar necrosis, and lower mortality in rodent pancreatitis. Am J Surg 1993; 165: 40–5
  • Niederau C, Crass R A, Silver G, Ferrell L D, Grendell J H. Therapeutic regimens in acute experimental hemorrhagic pancreatitis. Effects of hydration, oxygenation, peritoneal lavage, and a potent protease inhibitor. Gastroenterology 1988; 95: 1648–57
  • Widdison N D, Karanjia N D, Reber H A. Antimicrobial treatment of pancreatic infection in cats. Br J Surg 1994; 81: 886–9
  • Runkel N S, Rodriguez L F, Moody F G. Mechanisms of sepsis in acute pancreatitis in opossums. Am J Surg 1995; 169: 227–32
  • Medich D S, Lee T K, Melhem M F, Rowe M I, Schraut W H, Lee KKW. Pathogenesis of pancreatic sepsis. Am J Surg 1993; 165: 46–51
  • Foitzik T, Fernandez-del Castillo C, Ferraro M J, Mithofer K, Rattner D W, Warshaw A L. Pathogenesis and prevention of early pancreatic infection in experimental acute necrotizing pancreatitis. Annal Surg 1995; 222: 179–85
  • Pederzoli P, Bassi C, Vesentini S, Campedelli A. A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstetr 1993; 176: 480–83

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.