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Original Article

Protoporphyrin-IX Distribution and Photodynamic Effect in Rat Oesophagus after Aminolevulinic Acid Administration

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Pages 633-637 | Received 29 Nov 1996, Accepted 10 Mar 1997, Published online: 08 Jul 2009

References

  • Evrard S, Aprahamian M, Marescaux J. Intra-abdominal photo-dynamic therapy: from theory to feasibility. Br J Surg 1993; 80: 298–303
  • Chatlani P T, Nuutimen PJO, Toda N, Barr H, MacRoberts A J, Bedwell J, et al. Selective necrosis in hamster pancreatic tumours using photodynamic therapy with phtalocyanine photo-sensitization. Br J Surg 1992; 79: 786–90
  • Murray R K. Porphyrins & bile pigments. Harper's biochemistry, RK Murray, DK Granner, PA Mayes, VW Rodwell. Appleton & Lange, East Norwalk (CT) 1990; 318–31
  • Loh C S, Vernon D, MacRobert A J, Bedwell J, Bown S G, Brown S B. Endogenous porphyrin distribution induced by 5-amino-levulinic acid in the tissue layers of the gastrointestinal tract. J Photochem Photobiol [Biol] 1993; 20: 47–54
  • Loh C S, MacRobert A J, Bedwell J, Regula J, Krasner N, Bown S G. Oral versus intravenous administration of 5-aminolevulinic acid for photodynamic therapy. Br J Cancer 1993; 68: 41–51
  • Bedwell J, MacRobert A J, Phillips D, Bown S G. Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model. Br J Cancer 1992; 65: 818–24
  • Savitski A P, Vorobyova E V, Berezin I V, Ugarova N N. Acid-base properties of protoporphyrin IX; its dimethyl ester and heme solubilized on surfactant micelles: spectrophotometric and fluorometric titration. J Colloid Interface Sci 1981; 84: 175–81
  • Loh C S, Bedwell J, MacRobert A J, Krasner N, Phillips D, Bown S G. Photodynamic therapy of the normal rat stomach: a comparative study between disulphonated aluminium phtalocyanine and 5-aminolevulinic acid. Br J Cancer 1992; 66: 452–62
  • Karanov S, Shopova M, Getov H. Photodynamic therapy in gastrointestinal cancer. Lasers Surg Med 1991; 11: 395–8
  • Overholt B, Panjehpour M, Tefftellar E, Rose M. Photodynamic therapy for treatment of early adenocarcinoma in Barrett's esophagus. Gastrointest Endosc 1993; 39: 73–6
  • Overholt B F, Panjehpour M. Photodynamic therapy for Barrett's esophagus: Clinical update. Am J Gastroenterol 1996; 91: 1719–23
  • Regula J, MacRobert A J, Gorchein A, Buonaccorsi G A, Thorpe S M, Spencer G M, et al. Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolevulinic acid induced protoporphyrin IX–a pilot study. Gut 1995; 36: 67–75
  • Barr H, Tralau C J, MacRobert A J, Krasner N, Boulos P B, Clark C G, et al. Photodynamic therapy in the normal rat colon with phthalocyanine sensitation. Br J Cancer 1987; 56: 111–8

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