34
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Increased Expression of Costimulatory Molecules on Peripheral Blood Monocytes in Patients with Crohn's Disease

, , &
Pages 1241-1246 | Received 05 May 1997, Accepted 11 Sep 1997, Published online: 08 Jul 2009

References

  • MacDermott R. P., Stenson W. F. Alterations of the immune system in ulccrative colitis and Crohn's disease. Adv Immunol 1988; 42: 285–328
  • Schreiber S., Raedler A., Stenson W. F., MacDermott R. P. The role of the mucosal immune system in inflammatory bowel disease. Gastroenterol Clin North Am 1992; 21: 451–502
  • Mueller C. H., Knoflash P., Zielinski C. C. T-cell activation in Crohn's disease. Increased levels of soluble interleukin-2 receptor in serum and in supernatants of stimulated peripheral blood mononuclear cells. Gastroenterology 1990; 98: 639–46
  • Pallone F., Fuis S., Squarcia O., Bianocc L., Pozzilli P., Boirivant M. Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined as by the expression of early activation antigens. Gut 1987; 28: 745–53
  • Roman L. I., Manzano L., Hera A., Abreu L., Rossi I., Alvarez-Mon M. Expanded CD4+ CD45RO+ phenotype and defective proliferative response in T lymphocytes from patients with Crohn's disease. Gastroentcrology 1996; 110: 1008–19
  • Liu Z. X., Noguchi M., Hiwatashi N., Toyoda T. Monocyte aggregation and multinucleated giant-cell formation in vitro in Crohn's disease. The effect of cell adhesion molecules. Scand J Gastroenterol 1996; 31: 706–10
  • Baldassano R. N., Schreiber S., Johnston R. B., Fu R. D., Muraki T., MacDermott R. P. Crohn's disease monocytes are primed for accentuated release of toxic oxygen metabolites. Gastroenterology 1993; 105: 60–6
  • Burgio V. E., Fais S., Boirivant M., Perrone A., Pallone F. Peripheral monocytes and naive T-cell recruitment and activation in Crohn's disease. Gastroenterology 1995; 109: 1029–38
  • Van Seventer G. A., Shimizu Y., Shaw S. Roles of multiple accessary molecules in T cell activation. Curr Opin Immunol 1991; 3: 361–72
  • Allison J. P. CD28-B7 interaction in T-cell activation. Curr Opin Immunol 1994; 6: 414–9
  • June C. H., Bluestone J. A., Nudler C. M., Tompson C. The B7 and CD28 receptor families. Immunol Today 1994; 15: 321–31
  • Best W. R., Becktel J. M., Singelton J. W., Kern F., Jr. Development of a Crohn's disease activity index. National cooperative Crohn's disease study. Gastroenterology 1976; 70: 439–44
  • Truelove S. C., Witts L. J. Cortisone in ulcerative colitis. Final report on a therapeutic trial. Br Med J 1955; 2: 1041–8
  • Selby W. S., Jewell D. P. T lymphocyte subsets in inflammatory bowel disease: peripheral blood. Gut 1983; 24: 99–106
  • Senju M., Hulstaert F., Jewell D. P. Flow cytometric analysis of peripheral blood lymphocytes in ulcerative colitis and Crohn's disease. Gut 1991; 32: 779–83
  • Chaux P., Moutet M., Faivre J., Martin F., Martin M. Inflammatory cells infiltrating human colorectal carcinomas express HLá class II but not B7–1 and B7–2 costimulatory molecules of the T-cell activation. Lab Invest 1996; 74: 975–83
  • Springer T. A. Adhesion receptors of immune system. Nature 1990; 346: 425–33
  • Dubey C., Croft M., Swain S. L. Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7–1 can costimulate naive CD4 T cell activation but are required for optium response. J Immunol 1995; 155: 45–57
  • Van Seventer G. A., Shimizu Y., Morgan K. J., Shaw S. The LFA-1 ligand ICAM-1 provides an important costimulating signal for T cell receptor-mediated activation of resting T cells. J Immunol 1990; 144: 4579–86
  • Mallizia G., Calabrese A., Cottone M., Ramondo M., Trejdosiewie Z. L., Smart J., et al. Expression of leukocyte adhesion molecules by mononuclear phagocytes in inflammatory bowel disease. Gastroenterology 1991; 100: 150–9
  • Jones S. C., Banks R. E., Haidar A., Gearing A. J H, Hemingway I. K., Ibbotson S. H., et al. Adhesion molecules in inflammatory bowel disease. Gut 1995; 36: 724–30
  • Greenfield S. M., Hamblin A., Punchard N. A., Thompson R. P H. Expression of adhesion molecules on circulating leukocytes in patients with inflammatory bowel disease. Clin Sci 1992; 83: 221–6
  • Collins C. E., Davies C., Macey M. G., McCarthy D. A., Rampton D. S. Increased expression of circulating leukocyte adhesion molecules CD11b and CD 18 in inflammatory bowel disease. Gastroenterology 1996; 110: A885
  • Gardiner K. R., Crockard A. D., Halliday M. I., Rowlands B. J. Class II major histocompatibility complex antigen expression on peripheral blood monocytes in patients with inflammatory bowel disease. Gut 1994; 35: 511–6
  • Ayala A., Perrin M. M., Chaudry I. H. Defective macrophage antigen presentation following hemorrhage is associated with the loss of MHC class II (Ta) antigens. Immunology 1990; 70: 33–9
  • Mullin G., Lazenby A. J., Harris M. L., Bayless T. M., James S. P. Increased interleukin 2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis. Gastroenterology 1992; 102: 1620–7
  • MacDonald T. T., Hutchings P., Choy M. Y., Murch S., Cooke A. Tumor necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 1990; 81: 301–5
  • Fuss I. J., Neurath M., Boirivant M., Klein J. S., Motte C. D L, Strong S. A., et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. J Immunol 1996; 157: 1261–70
  • Bouma G., Oudkerk Pool M., Scharenberg J. G M, Kolkman J. J., Von Blomberg B. M E, Scheper R. J., et al. Differences in the intrinsic capacity of peripheral blood mononuclear cells to produce tumor necrosis factor alpha and beta in patients with inflammatory bowel disease and healthy controls. Scand J Gastroenterol 1996; 30: 1095–100

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.