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Scandinavian Journal of Infectious Diseases Volume 42, 2010 - Issue 4
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ORIGINAL ARTICLE

Evaluation of neutrophilic CD64, interleukin 10 and procalcitonin as diagnostic markers of early- and late-onset neonatal sepsis

Alaa A.H. Zeitoun Paediatric Department
,
Suzan S. Gad Paediatric Department
,
Fadia M. Attia Clinical Pathology Department, Faculty of Medicine, Suez Canal University, EgyptCorrespondence[email protected] [email protected]
,
Asmaa S. Abu Maziad Paediatric Department
&
Edward F. Bell Pediatric Department, Carver College of Medicine, University of Iowa, Iowa, USA
Pages 299-305 | Received 14 Aug 2009, Accepted 29 Oct 2009, Published online: 19 Jan 2010

References

  • Palazzi D, Klein J, Baker C. Bacterial sepsis and meningitis. Remington JS, Klein JO, Wilson CB, Baker CJ. Infectious diseases of the fetus and newborn infant. 6th. Philadelphia: Elsevier Saunders; 2006. 247–95.
  • Moore KL, Kainer MA, Badrawi N, Afifi S, Wasfy M, Bashir M, . Neonatal sepsis in Egypt associated with bacterial contamination of glucose-containing intravenous fluids. Pediatr Infect Dis J 2005;24:590–4.
  • Ng P. Diagnostic markers of infections in neonates. Arch Dis Child Fetal Neonatal Ed 2004;89:229–35.
  • Franz A, Kron M, Pohlandt F, Steinbach G. Comparison of procalcitonin with interleukin 8, C-reactive protein and differential white blood cell count for the early diagnosis of bacterial infections in newborn infants. Pediatr Infect Dis J 1999;18:666–71.
  • Turner D, Hammerman C, Rudensky B, Schlesinger Y, Goia C, Schimmel MS. Procalcitonin in preterm infants during the first few days of life: introducing an age related normo-gram. Arch Dis Child Fetal Neonatal Ed 2006;91:F283–6.
  • Khassawneh M, Hayajneh WA, Kofahi HH, Khader Y, Amarin Z, Daoud A. Diagnostic markers for neonatal sepsis: comparing C-reactive protein, interleukin-6 and immunoglobulin M. Scand J Immunol 2007;65:171–5.
  • Vigushin D, Pepys M, Hawkins P. Metabolic and scinti-graphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 1993;91:1351–7.
  • Pourcyrous M, Bada H, Korones S, Baselski V, Wong Seok P. Significance of serial C reactive protein responses in neonatal infection and other disorders. Pediatrics 1993;92:431–5.
  • Moore K, Malefyt R, Coffman R, O’Garra A. Interleukin-10 and interleukin-10 receptor. Annu Rev Immunol 2001;19:683–765.
  • Ng P, Li K, Wong R, Chui K, Wong E, Fok T. Neutrophil CD64 expression: a sensitive diagnostic marker for late-onset nosocomial infection in very low birthweight infants. Pediatr Res 2002;51:296–303.
  • Ng P, Lam C, Li A, Wong C, Cheng F, Leung TF, . Inflammatory cytokine profile in children with severe acute respiratory syndrome. Pediatrics 2004;113:e7–14.
  • Van Rossum A, Wulkan R, Oudesluys-Murphy A. Procalcitonin as an early marker of infection in neonates and children. Lancet Infect Dis 2004;4:620–30.
  • Lam H, Ng P. Biochemical markers of neonatal sepsis. Pathology 2008;40:141–8.
  • Rodwel RL, Leslie AL, Tudehope DI. Early diagnosis of neonatal sepsis using a hematologic scoring system. J Pediatr 1988;112:761–7.
  • Töllner U. Early diagnosis of septicemia in the newborn. Clinical studies and sepsis score. Eur J Pediatr 1982;138:331–7.
  • Ng PC, Li G, Chui KM, Chu WC, Li K, Wong RP, . Neutrophil CD64 is a sensitive diagnostic marker for early-onset neonatal infection. Pediatr Res 2004;56:1–9.
  • Enguix A, Rey C, Concha A, Medina A, Coto D, Dieguez MA. Comparison of procalcitonin with C-reactive protein and serum amyloid for the early diagnosis of bacterial sepsis in critically ill neonates and children. Intensive Care Med 2001;27:211–5.
  • Resch B, Gusenleitner W, Muller W. Procalcitonin and inter-leukin-6 in the diagnosis of early-onset sepsis of the neonate. Acta Pediatr 2003;92:243–5.
  • Fendler W, Piotrowski A. Procalcitonin in the early diagnosis of nosocomial sepsis in preterm neonates. J Paediatr Child Health 2008;44:114–8.
  • Chiesa C, Pellegrini G, Panero A, Osborn JF, Signore F, Assumma M, . C-reactive protein, interleukin-6, and procalcitonin in the immediate postnatal period: influence of illness severity, risk status, antenatal and perinatal complications, and infection. Clin Chem 2003;49:60–8.
  • Turner D, Hammerman C, Rudensky B, Schlesinger Y, Schimmel MS. The role of procalcitonin as a predictor of nosocomial sepsis in preterm infants. Acta Pediatr 2006;95:1571–6.
  • Ng PC, Li K, Leung TF, Wong RP, Li G, Chui KM, . Early prediction of sepsis-induced disseminated intravascular coagulation with interleukin-10, interleukin-6, and RANTES in preterm infants. Clin Chem 2006;52:1181–9.
  • Sherwin C, Broadbent R, Young S, Worth J, McCaffrey F, Medlicott NJ, . Utility of interleukin-12 and inter-leukin-10 in comparison with other cytokines and acute-phase reactants in the diagnosis of neonatal sepsis. Am J Perinatol 2008;25:629–36.

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