Advanced search
Publication Cover
Scandinavian Journal of Infectious Diseases Volume 42, 2010 - Issue 6-7
Submit an article Journal homepage
81
Views
3
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Prevalence of cagA and vacA genotypes of Helicobacter pylori isolated from Turkish patients with active or non-active chronic gastritis

Birol Safak Department of Microbiology and Clinical Microbiology
,
Ihsan Hakki Ciftci Department of Microbiology and Clinical MicrobiologyCorrespondence[email protected]
,
Fatma Husniye Dilek Department of Pathology
,
Ihsan Uslan Department of Gastroenterology
,
Zafer Cetinkaya Department of Microbiology and Clinical Microbiology
,
Gulsah Asik Department of Microbiology and Clinical Microbiology
&
Osman Nuri Dilek Department of Surgery, Faculty of Medicine, Kocatepe University, Afyonkarahisar, Turkey
 show all
Pages 435-438 | Received 13 Jun 2009, Accepted 15 Dec 2009, Published online: 08 Feb 2010

References

  • Kusters JG, van Vliet AH, Kuipers EJ. Pathogenesis of Helicobacter pylori infection. Clin Microbiol Rev 2006;19:449–90.
  • Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002;347:1175–86.
  • Nogueira C, Figueiredo C, Carneiro F, Gomes AT, Barreira R, Figueira P, . Helicobacter pylori genotypes may determine gastric histopathology. Am J Pathol 2001;158:647–54.
  • Ye GA, Zhang WD, Lui LM, Shi L, Xu ZM, Chen Y, . vacA gene of Helicobacter pylori. Shijie Huaren Xia Ohuma Zazhi 2001;9:593–5.
  • Van Doorn LJ, Figueredo C, Sanna R. Expanding allelic diversity of Helicobacter pylori vacA. J Clin Microbiol 1998;36:2597–603.
  • Crabtree JE, Covacci A, Farmery SM, Xiang Z, Tompkins DS, Perry S, . Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with cagA positive phenotype. J Clin Pathol 1995;48:41–5.
  • Basso D, Zambon CF, Letley DP, Stranges A, Marchet A, Rhead JL, . Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology 2008;135:91–9.
  • Demirtürk L, Ozel AM, Yazgan Y, Solmazgül E, Yildirim S, Gültepe M, . cagA status in dyspeptic patients with and without peptic ulcer disease in Turkey: association with his-topathologic findings. Helicobacter 2001;6:163–8.
  • Dixon MF, Genta RM, Yardely JH, Correa P. Classification and grading of gastritis. The Updated Sydney System. Am J Surg Pathol 1996;20:1161–81.
  • Kuipers EJ, Uyterlinde AM, Peña AS, Roosendaal R, Pals G, Nelis GF, . Long-term sequelae of Helicobacter pylori gastritis. Lancet 1995;345:1525–8.
  • Makola D, Peura DA, Crowe SE. Helicobacter pylori infection and related gastrointestinal diseases. J Clin Gastroenterol 2007;41:548–58.
  • Wada A, Yamasaki E, Hirayama T. Helicobacter pylori vacuolating cytotoxin, vacA, is responsible for gastric ulceration. J Biochem 2004;136:741–6.
  • Kalebi A, Rana F, Mwanda W, Lule G, Hale M. Histopatho-logical profile of gastritis in adult patients seen at a referral hospital in Kenya. World J Gastroenterol 2007;13:4117–21.
  • Gatti LL, Lábio R, Silva LC, Smith Mde A, Payão SL. cagA positive Helicobacter pylori in Brazilian children related to chronic gastritis. Braz J infect Dis 2006;10:254–8.
  • Scholte GH, van Doorn LJ, Cats A, Bloemena E, Lindeman J, Quint WG, . Genotyping of Helicobacter pylori in paraffin-embedded gastric biopsy specimens: relation to histological parameters and effects on therapy. Am J Gastroenterol 2002;97:1687–95.
  • Akyön Y, Hascelik G. The effect of Helicobacter pylori on neutrophil chemotaxis is independent of cagA. FEMS immunol Med Microbiol 1999;24:209–13.
  • Mera R, Fontham ET, Bravo LE, Bravo JC, Piazuelo MB, Camargo MC, . Long term follow up of patients treated for Helicobacter pylori infection. Gut 2005;54:1536–40.
  • Maaroos Hi, Vorobjova T, Sipponen P, Tammur R, Uibo R, Wadström T, . An 18-year follow-up study of chronic gastritis and Helicobacter pylori association of cagA positiv-ity with development of atrophy and activity of gastritis. Scand J Gastroenterol 1999;34:864–9.
  • Rieder G, Einsiedl W, Hatz RA, Stolte M, Enders GA, Walz A. . Comparison of CXC chemokines ENA-78 and interleukin-8 expression in Helicobacter pylori-associated gastritis. Infect Immun 2001;69:81–8.
  • Fischer W, Püls J, Buhrdorf R, Gebert B, Odenbreit S, Haas R. Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for cagA translocation in host cells and induction of interleukin-8. Mol Microbiol 2001;42:1337–48.
  • Zambon CF, Basso D, Navaglia F, Belluco C, Falda A, Fogar P, . Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome. Cytokine 2005;29:141–52.
  • Erzin Y, Koksal V, Altun S, Dobrucali A, Aslan M, Erdamar S, . Prevalence of Helicobacter pylori vacA, cagA, cagE, iceA, babA2 genotypes and correlation with clinical outcome in Turkish patients with dyspepsia. Helicobacter 2006;11:574–80.
  • van Doorn LJ, Henskens Y, Nouhan N, Verschuuren A, Vreede R, Herbink P, . The efficacy of laboratory diagnosis of Helicobacter pylori infections in gastric biopsy specimens is related to bacterial density and vacA, cagA, and iceA genotypes. J Clin Microbiol 2000;38:13–7.
  • Brooks HJ, Ahmed D, Mc Connell MA, Barbezat GO. Diagnosis of Helicobacter pylori infection by polymerase chain reaction: is it worth it? Diagn Microbiol infect Dis 2004; 50:1–5.
  • Fabre R, Sobhani I, Laurent-Puig P, Hedef N, Yazigi N, Vissuzaine C, . Polymerase chain reaction assay for the detection of Helicobacter pylori in gastric biopsy specimens: comparison with culture, rapid urease test, and histopathological tests. Gut 1994;35:905–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.