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Case Reports

Successful salvage therapy with inhaled zanamivir in a patient with peramivir-resistant pandemic influenza A (H1N1) 2009 virus

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Pages 151-155 | Received 02 Aug 2010, Accepted 04 Aug 2010, Published online: 21 Sep 2010

References

  • Centers for Disease Control and Prevention. Antiviral treatment options, including intravenous peramivir, for treatment of influenza in hospitalized patients for the 2009–2010 season. Atlanta, GA: CDC; 2010. Available at: http://www.cdc.gov/h1n1flu/EUA/peramivir_recommendations.htm (accessed August 2010).
  • Food and Drug Administration, Department of Health and Human Services. Emergency use authorization (EUA) for the investigational antiviral drug peramivir. Silver Spring, MD: FDA; 2010. Available at: http://www.fda.gov/downloads/Drugs/DrugSafety/PostmarketDrugSafetyInformationfor PatientsandProviders/UCM187800 (accessed August 2010).
  • Lackenby A, Democratis J, Siqueira MM, Zambon MC. Rapid quantitation of neuraminidase inhibitor drug resistance in influenza virus quasispecies. Antivir Ther 2008;13:809–20.
  • Deyde VM, Sheu TG, Trujillo AA, Okomo-Adhiambo M, Garten R, Klimov AI, . Detection of molecular markers of drug resistance in 2009 pandemic influenza A (H1N1) viruses by pyrosequencing. Antimicrob Agents Chemother 2010;54:1102–10.
  • Yang IS, Lee JY, Lee JS, Mitchell WP, Oh HB, Kang C, Kim KH. Influenza sequence and epitope database. Nucleic Acids Res 2009;37:D423–30.
  • Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, . Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 2009;325:197–201.
  • World Health Organization. Oseltamivir-resistant pandemic (H1N1) 2009 influenza virus, October 2009. Wkly Epidemiol Rec 2009;84:453–9.
  • Gubareva LV, Webster RG, Hayden FG. Detection of influenza virus resistance to neuraminidase inhibitors by an enzyme inhibition assay. Antiviral Res 2002;53:47–61.
  • Memoli MJ, Hrabal RJ, Hassantoufighi A, Eichelberger MC, Taubenberger JK. Rapid selection of oseltamivir- and peramivir-resistant pandemic H1N1 virus during therapy in 2 immunocompromised hosts. Clin Infect Dis 2010;50:1252–5.
  • Weinstock DM, Gubareva LV, Zuccotti G. Prolonged shedding of multidrug-resistant influenza A virus in an immunocompromised patient. N Engl J Med 2003;348:867–8.
  • Ison MG, Gubareva LV, Atmar RL, Treanor J, Hayden FG. Recovery of drug-resistant influenza virus from immunocompromised patients: a case series. J Infect Dis 2006;193:760–4.
  • Kumar D, Morris MI, Kotton CN, Fischer SA, Michaels MG, Allen U, . Guidance on novel influenza A/H1N1 in solid organ transplant recipients. Am J Transplant 2010;10: 18–25.

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