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Research Article

Weekly chlorhexidine douche: does it reduce healthcare-associated bloodstream infections?

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Pages 697-703 | Received 16 Apr 2014, Accepted 30 May 2014, Published online: 19 Aug 2014

References

  • Barsanti MC, Woeltje KF. Infection prevention in the intensive care unit. Infect Dis Clin North Am 2009;23:703–25.
  • Miller SE, Maragakis LL. Central line-associated bloodstream infection prevention. Curr Opin Infect Dis 2012; 25:412–22.
  • O’Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, et al. Healthcare Infection Control Practices Advisory Committee (HICPAC). Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 2011;52:162–93.
  • Hocking C, Pirret AM. Using a combined nursing and medical approach to reduce the incidence of central line associated bacteraemia in a New Zealand critical care unit: a clinical audit. Intensive Crit Care Nurs 2013;29:137–46.
  • Sagana R, Hyzy RC. Achieving zero central line-associated bloodstream infection rates in your intensive care unit. Crit Care Clin 2013;29:1–9.
  • McLaws ML, Burrell AR. Zero risk for central line- associated bloodstream infection: are we there yet? Crit Care Med 2012;40:388–93.
  • Khalid I, Al Salmi H, Qushmaq I, Al Hroub M, Kadri M, Qabajah MR. Itemizing the bundle: achieving and maintaining “zero” central line-associated bloodstream infection for over a year in a tertiary care hospital in Saudi Arabia. Am J Infect Control 2013;41:1209–13.
  • Kim JS, Holtom P, Vigen C. Reduction of catheter-related bloodstream infections through the use of a central venous line bundle: epidemiologic and economic consequences. Am J Infect Control 2011;39:640–6.
  • Montecalvo MA, McKenna D, Yarrish R, Mack L, Maguire G, Haas J, et al. Chlorhexidine bathing to reduce central venous catheter-associated bloodstream infection: impact and sustainability. Am J Med 2012;125:505–11.
  • Bleasdale SC, Trick WE, Gonzalez IM, Lyles RD, Hayden MK, Weinstein RA. Effectiveness of chlorhexidine bathing to reduce catheter-associated bloodstream infections in medical intensive care unit patients. Arch Intern Med 2007;167:2073–9.
  • Dixon JM, Carver RL. Daily chlorohexidine gluconate bathing with impregnated cloths results in statistically significant reduction in central line-associated bloodstream infections. Am J Infect Control 2010;38:817–21.
  • Climo MW, Sepkowitz KA, Zuccotti G, Fraser VJ, Warren DK, Perl TM, et al. The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crit Care Med 2009; 37:1858–65.
  • Popovich KJ, Hota B, Hayes R, Weinstein RA, Hayden MK. Effectiveness of routine patient cleansing with chlorhexidine gluconate for infection prevention in the medical intensive care unit. Infect Control Hosp Epidemiol 2009;30:959–63.
  • Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J. Effect of chlorhexidine whole-body bathing on hospital acquired infections among trauma patients. Arch Surg 2010;145:240–6.
  • Munoz-Price LS, Dezfulian C, Wyckoff M, Lenchus JD, Rosalsky M, Birnbach DJ, et al. Effectiveness of stepwise interventions targeted to decrease central catheter-associated bloodstream infections. Crit Care Med 2012;40:1464–9.
  • McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999; 12:147–79.
  • Karki S, Cheng AC. Impact of non-rinse skin cleansing with chlorhexidine gluconate on prevention of healthcare- associated infections and colonization with multi-resistant organisms: a systematic review. J Hosp Infect 2012;82:71–84.
  • Rupp ME, Cavalieri RJ, Lyden E, Kucera J, Martin M, Fitzgerald T, et al. Effect of hospital-wide chlorhexidine patient bathing on healthcare-associated infections. Infect Control Hosp Epidemiol 2012;33:1094–100.
  • Munoz-Price LS, Hota B, Stemer A, Weinstein RA. Prevention of bloodstream infections by use of daily chlorhexidine baths for patients at a long-term acute care hospital. Infect Control Hosp Epidemiol 2009;30:1031–5.
  • Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309–32.
  • Holder C, Zellinger M. Daily bathing with chlorhexidine in the ICU to prevent central line-associated bloodstream infections. J Clin Outcomes Manage 2009;16:509–13.
  • O’Horo JC, Silva GL, Munoz-Price LS, Safdar N. The efficacy of daily bathing with chlorhexidine for reducing healthcare-associated bloodstream infections: a meta-analysis. Infect Control Hosp Epidemiol 2012;33:257–67.
  • Marschall J, Mermel LA, Classen D, Arias KM, Podgorny K, Anderson DJ, et al. Strategies to prevent central line- associated bloodstream infections in acute care hospitals. Infect Control Hosp Epidemiol 2008;29(Suppl 1):S22–30.
  • DiGiovine B, Chenoweth C, Watts C, Higgins M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med 1999;160:976–81.
  • Warren DK, Quadir WW, Hollenbeak CS, Elward AM, Cox MJ, Fraser VJ. Attributable cost of catheter associated bloodstream infection among intensive care patients in a nonteaching hospital. Crit Care Med 2006;34:2084–9.
  • Mermel LA. Prevention of intravascular catheter related infections. Ann Intern Med 2000;132:391–402.
  • Popovich KJ, Lyles R, Hayes R, Hota B, Trick W, Weinstein RA, et al. Relationship between chlorhexidine gluconate skin concentration and microbial density on the skin of critically ill patients bathed daily with chlorhexidine gluconate. Infect Control Hosp Epidemiol 2012;33:889–96.
  • Vernon MO, Hayden MK, Trick WE, Hayes RA, Blom DW, Weinstein RA. Chlorhexidine gluconate to cleanse patients in a medical intensive care unit: the effectiveness of source control to reduce the bioburden of vancomycin-resistant enterococci. Arch Intern Med 2006;166:306–12.
  • Larson EL, Ciliberti T, Chantler C, Abraham J, Lazaro EM, Venturanza M, et al. Comparison of traditional and disposable bed baths in critically ill patients. Am J Crit Care 2004;13:235–41.
  • Soma VL, Qin X, Zhou C, Adler A, Berry JE, Zerr DM. The effects of daily chlorhexidine bathing on cutaneous bacterial isolates: a pilot study. Infect Drug Resist 2012;5:75–8.
  • Naparstek L, Carmeli Y, Chmelnitsky I, Banin E, Navon-Venezia S. Reduced susceptibility to chlorhexidine among extremely-drug-resistant strains of Klebsiella pneumoniae. J Hosp Infect 2012;81:15–19.
  • Fraud S, Campigotto AJ, Chen Z, Poole K. MexCD-OprJ multidrug efflux system of Pseudomonas aeruginosa: involvement in chlorhexidine resistance and induction by membrane-damaging agents dependent upon the AlgU stress response sigma factor. Antimicrob Agents Chemother 2008;52:4478–82.

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