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Original Article

Amca (Aminomethyl Cyclohexane Carboxylic Acid, Cyklo-Kapron®) a Potent Haemostatic Agent in Urinary Tract Bleeding

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Pages 169-176 | Received 01 May 1969, Published online: 09 Jul 2009

References

  • Andersson L. Treatment of so-called essential haematuria with fibrinolytic inhibitor (Epsilon-amino-caproic acid). Acta Chir Scand 1962a; 124: 355
  • Andersson L. Studies on fibrinolysis in urinary tract disease and its treatment with epsilon-amino-caproic acid. Acta Chir Scand 1962b; 21, Suppl. 301
  • Andersson L. Antifibrinolytic treatment with ep-silon-amino-caproic acid in connection with prostatectomy. Acta Chir Scand 1964; 127: 552
  • Andersson L. Combined prophylaxis of haemorrhage and thrombosis after prostatectomy. Acta Chir Scand 1965; 130: 393
  • Andersson L., Nilsson I. M., Colleen S., Granstrand B., Melander B. Role of urokinase and tissue activator in sustaining bleeding and the management thereof with EACA and AMCA. Ann NY Acad Sci 1968; 146: 642
  • Andersson L., Nilsson I. M., Colleen S., Melander B., Granstrand B. (1965b) Effect of AMCA and EACA as inhibitors of urokinase and tissue activator. Symposium on Fibrinolysis, TokyoJapan, Sept. 10th, 1965, In press
  • Andersson L., Nilsson I. M., Liedberg G., Rybo G., Nilsson L., Eriksson O., Granstrand B., Melander B. Antifibrinolytika. Vergleichende Untersu-chungen von AMCA, EACA und PAMBA. 1969, In press
  • Andersson L., Nilsson I. M., Nilehn J. E., Hedner U., Granstrand B., Melander B. Experimental and clinical studies on AMCA, the antifibrinolytically active isomer of p-aminomethyl cyclohexane carboxylic acid. Scand J Haemal 1965a; 2: 230
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  • Itterbeek H., Van Vermylen J., Verstraete M. High obstruction of urine flow as a complication of the treatment with fibrinolysis inhibitors of haematuria in haemophiliacs. Acta Haemat (Basel) 1968; 39: 237
  • Ladehoff Aa., Otte E. Inhibitory effect of epsilon-amino caproic acid on fibrinolytic activity and bleeding in transvesical prostatectomy. Scand J Clin Lab Invest 1963; 15: 239
  • Lingårdh G., Andersson L. Clot retention in the kidneys as a probable cause of anuria during treatment of haematuria with epsilon-aminocaproic acid. Acta Med Scand 1966; 180: 469
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  • Melander B., Gliniecki G., Granstrand B., Hanshoff G. Biochemistry and toxicology of Amika-pron; the antifibrinolytically active isomer of AMCHA. Acta Pharmacol (København) 1965; 22: 340
  • Nilsson I. M., Andersson L., Björkman S. E. Epsilon-aminocaproic acid (E-ACA) as a therapeutic agent, based on 5 year's clinical experience. Acta Med Scand 1966; 448: 21, Suppl.
  • Nilsson I. M., Olow B. Fibrinolysis induced by streptokinase in man. Acta Chir Scand 1962; 123: 247
  • Okamoto S., Okamoto U. Amino-methyl-cyclo-hexane-carboxylic acid: AMCHA. A new potent inhibitor of the fibrinolysis. Keio J Med 1962; 11: 105
  • Rø J. S. Antifibrinolytisk terapi vid urinveis-blødninger. T Norsk Lægejoren 1968; 88: 1352
  • Sack E., Spaet T. H., Gentile R. L., Hudson P. B. Reduction of postprostatectomy bleeding by epsilon-aminocaproic acid. New Engl J Med 1962; 266: 541
  • Schmutzler R. Therapie der postoperativen Blu-tung beim Prostatiker unter besonderer Berücksichti-gung der Wirkung der Aminocapronsäure. Helv Chir Acta 1963; 30: 518
  • Stark S. N., White J. G., Langer L., Jr., Krivit W. Epsilon amino-caproic acid therapy as a cause of intrarenal obstruction in haematuria of haemophiliacs. Scand J Haemat 1965; 2: 99

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