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Scandinavian Journal of Urology and Nephrology Volume 16, 1982 - Issue 3
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Original Article

Pharmacokinetics of Methyldopa in Renal Failure and Bilaterally Nephrectomized Patients

Erik MyhreMedical Department B and Department of Clinical Pharmacology, University Hospital, Rikshospitalet, Oslo, Norway
,
Ørnulf StenbækMedical Department B and Department of Clinical Pharmacology, University Hospital, Rikshospitalet, Oslo, Norway
,
Hans Erik Rugstad,Medical Department B and Department of Clinical Pharmacology, University Hospital, Rikshospitalet, Oslo, Norway
,
Elisabeth Arnold,Department of Biology, Dumex Ltd., Copenhagen, Denmark
&
Tage HansenDepartment of Biology, Dumex Ltd., Copenhagen, Denmark
Pages 257-263 | Received 09 Jan 1981, Published online: 15 Feb 2010

REFERENCES

  • Brodwall, E. K., Myhre, E., Stenbæk, Ø. & Hansen, T. 1972. The effect of methyldopa on renal function in patients with renal failure. Acta Med Scand 191, 339.
  • Greenblatt, D. J. & Koch-Weser, J. 1975. Clinical pharmacokinetics. N Engl J Med 293, 702.
  • Hunt, J. C., Strong, C. G., Harrison, E. G., Furlow, W. L. & Leary, F. J. 1970. Management of hypertension of renal origin. Am Heart J 76, 280.
  • Myhre, E., Brodwall, E. K., Stenbæk, Ø. & Hansen, T. 1972a. The renal excretion of methyldopa. Scand J Clin Lab Invest 29
  • Myhre, E., Brodwall, E. K., Stenbæk, Ø. & Hansen, T. 1972b. Plasma turnover of methyldopa in advanced renal failure. Acta Med Scand 191, 343.
  • Sjoerdsma, A., Vendsalu, A. & Engelman, K. 1963. Studies on the metabolism and mechanism of action of methyldopa. Circulation 28, 492.
  • Stenbæk, Ø., Myhre, E., Brodwall, E. K. & Hansen, T. 1971. Hypotensive effect of methyldopa in renal failure associated with hypertension. Acta Med Scand 191, 333.
  • Stenbæk, Ø., Myhre, E., Rugstad, H. E., Arnold, E. & Hansen, T. 1977. Pharmacokinetics of methyldopa in normal man. Eur J Clin Pharmacol 12, 117.

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