Tamm–Horsfall protein gene is associated with distal tubular dysfunction in patients with type 1 diabetes

References

• Rasch R, Torffvit O, Bachman S, Jensen PK, Jacobsen NO. Tamm–Horsfall glycoprotein in streptozotocin diabetic rats: A study of kidney in situ hybridization, immunohistochemistry and urinary excretion. Diabetologia 1995;38:525–35.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Jørgensen PE, Kamper A-L, Hostein-Rathlou NH, Leyssac PP, Poulsen SS, Strandgaard S. Urinary excretion of Tamm–Horsfall protein and epidermal growth factor in chronic nephropathy. Nephron 1998;79:167–72.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Agardh C-D. Urinary excretion rate of NC1 and Tamm–Horsfall protein in the microalbuminuric type I diabetic patient. J Diabet Complications 1994;8:77–83.
   Google Scholar
• Ginevri F, Piccotti E, Alinovi R, DeToni T, Biagini C, Chifferi GM, Gusmano R. Reversible tubular proteinuria precedes microalbuminuria and correlates with the metabolic status in diabetic children. Pediatr Nephrol 1993;7:23–6.
   PubMed Web of Science ®Google Scholar
• Pfleiderer S, Zimmerhackl L, Kinne R, Manz F, Schuler G, Brandis M. Renal proximal and distal tubular function is attenuated in diabetes mellitus type 1 as determined by the renal excretion of α1-microglobulin and Tamm–Horsfall protein. Clin Invest 1993;71:972–7.
   PubMedGoogle Scholar
• Schultz C, Dalton R, Neil H, Konopelska-Bahu T, Dunger D, on behalf of the Oxford Regional Prospective Study Group. Markers of renal tubular dysfunction measured annually do not predict risk of microalbuminuria in the first few years after diagnosis of type 1 diabetes. Diabetologia 2001;44:224–9.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Melander O, Hultén UL. Urinary excretion rate of Tamm–Horsfall protein is related to salt intake in humans. Nephron Physiol 2004;97:31–6.
   Google Scholar
• Thorup C, Ollerstam A, Persson AEG, Torffvit O. Increased tubuloglomerular feedback activity is associated with increased NO production in the streptozotocin-diabetic rat. J Diabetes Complications 2000;14:46–52.
   PubMed Web of Science ®Google Scholar
• Mogensen C, Christensen CK. Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med 1984;311:89–93.
   PubMed Web of Science ®Google Scholar
• Rudberg S, Persson B, Dahlquist G. Increased glomerular filtration rate is a predictor of diabetic nephropathy – an 8-year prospective study. Kidney Int 1992;41:822–8.
   PubMed Web of Science ®Google Scholar
• Sejdiu I, Torffvit O. Decreased urinary concentration of Tamm–Horsfall protein is associated with development of renal failure and cardiovascular death within 20 years in type 1 but not in type 2 diabetic patients. Scand J Urol Nephrol 2008;42:168–74.
   PubMed Web of Science ®Google Scholar
• Holmquist P, Torffvit O, Jorgensen P, Torring N, Nexo E, Sjöblad S. Early urinary changes in Tamm–Horsfall protein and epidermal growth factor in diabetic children. Pediatr Nephrol 2001;16:488–92.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Edvinsson L. Blockade of nitric oxide decreases the renal vasodilatory effect of neuropeptide Y in the insulin-treated diabetic rat. Eur J Physiol 1997;434:445–50.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Edvinsson L. Relaxing effect of insulin in renal arteries from diabetic rats. Regul Pept 1999;79:147–52.
   PubMedGoogle Scholar
• Zanchi A, Moczulski D, Hanna L, Wantman M, Warram J, Krolewski AS. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism. Kidney Int 2000;57:405–13.
   PubMed Web of Science ®Google Scholar
• Möllsten A, Lajer M, Jorsal A, Tarnow L. The endothelial nitric oxide synthase gene and risk of diabetic nephropathy and development of cardiovascular disease in type 1 diabetes. Mol Genet Metab 2009;97:80–4.
   PubMed Web of Science ®Google Scholar
• Möllsten A, Wessman M, Svensson M, Forsblom C, Parkkonen M, Brismar K, Glu298Asp and NOS4ab polymorphisms in diabetic nephropathy. Ann Med 2006;38:522–8.
   PubMed Web of Science ®Google Scholar
• Wang X, Sim A, Badenhop R, McCredie R, Wilcken DE. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 1996;ii:41–5.
   Google Scholar
• Torffvit O, Agardh C-D, Kjellsson B, Wieslander J. Tubular secretion of Tamm–Horsfall protein in type 1 (insulin-dependent) diabetes mellitus using a simplified enzyme linked immunoassay. Clin Chim Acta 1992;205:31–41.
   PubMed Web of Science ®Google Scholar
• Raile K, Galler A, Hofer S, Herbst A, Dunstheimer D, Busch P, Holl RW. Diabetic nephropathy in 27805 children, adolescents, and adults with type 1 diabetes. Effect of diabetes duration, A1C, hypertension, dyslipidemia, diabetes onset, and sex. Diabetes Care 2007;30:2523–8.
   PubMed Web of Science ®Google Scholar
• Torffvit O, Agardh C-D. The impact of metabolic and blood pressure control on incidence and progression of nephropathy. A 10-year study of 385 type 2 diabetic patients. J Diabet Complications 2001;15:307–13.
   Google Scholar
• Borch-Johnsen K, Feldt-Rasmussen B, Strandgaard S, Schroll M, Jensen JS. Urinary albumin excretion. An independent predictor of ischemic heart disease. Arterioscler Thromb Vasc Biol 1999;19:1992–7.
   PubMed Web of Science ®Google Scholar
• Viberti G, Jarrett R, Mahmud U, Hill R, Argyropoulos A, Keen H. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet 1982;319:1430–2.
   Google Scholar
• Torffvit O, Rippe B. Size and charge selectivity of the glomerular filter in patients with insulin-dependent diabetes mellitus: urinary immunoglobulins and glycosaminoglycans. Nephron 1999;83:301–7.
   PubMed Web of Science ®Google Scholar
• Bangstad H-J, Kofoed-Enevoldsen A, Dahl-Jørgensen K, Hanssen KF. Glomerular charge selectivity and the influence of improved blood glucose control in Type 1 (insulin-dependent) diabetic patients with microalbuminuria. Diabetologia 1992;35:1165–9.
   PubMed Web of Science ®Google Scholar
• Thulesen J, Jørgensen P, Torffvit O, Nexø E, Poulsen SS. Urinary excretion of epidermal growth factor and Tamm–Horsfall protein in three rat models with increased renal excretion of urine. Regul Pept 1997;72:179–86.
   PubMedGoogle Scholar
• Lövestam-Adrian M, Hansson-Lundblad C, Torffvit O. Sight-threatening retinopathy is associated with lower mortality in type 2 diabetic subjects: a 10-year observation study. Diabetes Res Clin Pract 2007;77:141–7.
   PubMed Web of Science ®Google Scholar
• Catalano C, Torffvit O. Urinary excretion of Tamm–Horsfall protein in normotensive, normo-albuminuric type 1 diabetic patients. Nephron 1996;72:436–41.
   PubMed Web of Science ®Google Scholar
• Wang X, Mahaney M, Sim A, Wang J, Wang J, Blangero J, Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol 1997;17:3147–53.
   PubMed Web of Science ®Google Scholar
• Tsukada T, Yokoyama K, Arai T, Takemoto F, Hara S, Yamada A, Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans. Biochem Biophys Res Commun 1998;245:190–3.
   PubMed Web of Science ®Google Scholar