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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 3
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Animal Pharmacokinetics and Metabolism

Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol

In-Soo YoonCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
,
Min-Koo ChoiCollege of Pharmacy, Dankook University, San 29, Anseo-Dong, Chonan, Chungnam, South Korea
,
Jung Sun KimDivision of Health Science, Dongseo University, Busan, South KoreaCorrespondence[email protected]
,
Chang-Koo ShimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
,
Suk-Jae ChungCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
&
Dae-Duk KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
Pages 243-251 | Received 08 Sep 2010, Accepted 03 Nov 2010, Published online: 03 Dec 2010

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