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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 11
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Research Article

Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs

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Pages 975-987 | Received 19 Mar 2014, Accepted 10 May 2014, Published online: 30 May 2014

References

  • Arshad SH. (2005). Primary prevention of asthma and allergy. J Allergy Clin Immunol 116:3–14
  • Avdeef A. (1993). pH-metric log P. II: refinement of partition coefficients and ionization constants of multiprotic substances. J Pharm Sci 82:183–90
  • Baek IH, Chae JW, Song GY, Kwon KI. (2009). LC-MS/MS assay validation for a new immune modulator, JHL45, and its major metabolite in plasma: application to pharmacokinetic studies in rats. Bull Korea Chem Soc 30:2631–6
  • Blume-Peytavi U, Wahn U. (2011). Optimizing the treatment of atopic dermatitis in children: a review of the benefit/risk ratio of methylprednisolone aceponate. J Eur Acad Dermatol Venereol 25:508–15
  • Buddenkotte J, Steinhoff M. (2010). Pathophysiology and therapy of pruritus in allergic and atopic diseases. Allergy 65:805–21
  • Chan PL, Holford NH. (2011). Drug treatment effects on disease progression. Annu Rev Pharmacol Toxicol 41:625–59
  • D’Argenio DZ, Schumitzky A, Wang X. (2009). ADAPT 5 user’s guide: pharmacokinetic/pharmacodynamic systems analysis software. Los Angeles: Biomedical Simulations Resource
  • Dayneka NL, Garg V, Jusko WJ. (1993). Comparison of four basic models of indirect pharmacodynamics responses. J Pharmacokinet Biopharm 21:457–78
  • Di L, Kerns EH. (2003). Profiling drug-like properties in discovery research. Curr Opin Chem Biol 7:402–8
  • Dunstan JA, Brothers S, Bauer J, et al. (2011). The effects of Mycobacteria vaccae derivative on allergen-specific responses in children with atopic dermatitis. Clin Exp Immunol 164:321–9
  • Furue M, Chiba T, Takeuchi S. (2011). Current status of atopic dermatitis in Japan. Asia Pac Allergy 1:64–72
  • Gao F, Johnson DL, Ekins S, et al. (2002). Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC50. J Biomol Screen 7:373–82
  • Godfrey KR, Arundel PA, Dong Z, Bryant R. (2011). Modelling the double peak phenomenon in pharmacokinetics. Comput Methods Programs Biomed 104:62–9
  • Holloway JW, Yang IA, Holgate ST. (2010). Genetics of allergic disease. J Allergy Clin Immunol 125:S81–94
  • Jung DJ, Porzel A, Huneck S. (1991). Gigasol and other coumarins from Angelica gigas. Phytochemistry 30:710–12
  • Kansy M, Senner F, Gubernator K. (1998). Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. J Med Chem 41:1007–10
  • Kerns EH. (2001). High throughput physicochemical profiling for drug discovery. J Pharm Sci 90:1838–58
  • Krzyzanski W, Jusko WJ. (1998). Characterization of pharmacodynamic recession slopes for direct and indirect response models. J Pharmacokinet Biopharm 26:409–36
  • Lee J, Bielory L. (2010). Complementary and alternative interventions in atopic dermatitis. Immunol Allergy Clin North Am 30:411–24
  • Lee JH, Choi YS, Kim JH, et al. (2006). A mass preparation method of (+)-decursinol from the roots of Angelica gigas. J Pharm Soc Korea 50:338–44
  • Lee JS, Kim IS, Ryu JS, et al. (2011). The inhibitory effect of Duchesnea chrysantha extract on the development of atopic dermatitis-like lesions by regulating IgE and cytokine production in Nc/Nga mice. Phytother Res 26:284–90
  • Lehr T, Staab A, Tillmann C, et al. (2009). A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam. Clin Pharmacokinet 48:529–42
  • Lipinski CA. (2000). Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Methods 44:235–49
  • Matsuda H, Watanabe N, Geba GP, et al. (1997). Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice. Int Immunol 9:461–6
  • McGonigle P, Ruggeri B. (2014). Animal models of human disease: challenges in enabling translation. Biochem Pharmacol 87:162–71
  • Novak N. (2009). New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 64:265–75
  • Novak N, Simon D. (2011). Atopic dermatitis – from new pathophysiologic insights to individualized therapy. Allergy 66:830–9
  • Okusanya O, Forrest A, DiFrancesco R, et al. (2007). Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks. Antimicrob Agents Chemother 51:1822–6
  • Plötz SG, Ring J. (2010). What's new in atopic eczema? Expert Opin Emerg Drugs 15:249–67
  • Sheiner LB, Stanski DR, Vozeh S, et al. (1979). Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 25:358–71
  • Smith DA, Di L, Kerns EH. (2010). The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery. Nat Rev Drug Discov 9:929–39
  • Son CY, Baek IH, Song GY, et al. (2009). Pharmacological effect of decursin and decursinol angelate from Angelica gigas Nakai. J Pharm Soc Korea 53:303–13
  • Song JS, Chae JW, Lee KR, et al. (2011). Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats. Xenobiotica 41:895–902
  • Ständer S, Luger TA. (2010). Itch in atopic dermatitis – pathophysiology and treatment. Acta Dermatovenerol Croat 18:289–96
  • Strachan DP. (1999). Lifestyle and atopy. Lancet 353:1457–8
  • Stuart M, Box K. (2005). Chasing equilibrium: measuring the intrinsic solubility of weak acids and bases. Anal Chem 77:983–90
  • Suto H, Matsuda H, Mitsuishi K, et al. (1999). NC/Nga mice: a mouse model for atopic dermatitis. Int Arch Allergy Immunol 120:70–5
  • Svensson A, Chambers C, Gånemo A, Mitchell SA. (2011). A systematic review of tacrolimus ointment compared with corticosteroids in the treatment of atopic dermatitis. Curr Med Res Opin 27:1395–406
  • Wang Y, Roy A, Sun L, Lau CE. (1999). A double-peak phenomenon in the pharmacokinetics of alprazolam after oral administration. Drug Metab Dispos 27:855–9
  • Xu R, Nemes C, Jenkins KM, et al. (2002). Application of parallel liquid chromatography/mass spectrometry for high-throughput microsomal stability screening of compound libraries. J Am Soc Mass Spectrom 13:155–65
  • Yamanaka K, Mizutani H. (2011). The role of cytokines/chemokines in the pathogenesis of atopic dermatitis. Curr Probl Dermatol 41:80–92
  • Yang EJ, Song GY, Lee JS, et al. (2009). A novel (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl-ester, inhibits ovalbumin-induced lung inflammation in a mouse model of asthma. Biol Pharm Bull 32:444–9
  • Yee S. (1997). In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man—fact or myth. Pharm Res 14:763–6

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