References
- Badolo L, Rasmussen LM, Hansen HR, Sveigaard C. (2010). Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension. Eur J Pharm Sci 40:282–8
- Bowen WP, Carey JE, Miah A, et al. (2000). Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos 28:781–8
- Dvorak Z, Modriansky M Pichard-Garcia L, et al. (2003). Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9 and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. Mol Pharmacol 64:160–9
- Dvorak Z, Pavek P. (2010). Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids. Drug Metab Rev 42:621–35
- Eloranta JJ, Meier PJ, Kullak-Ublick GA. (2005). Coordinate transcriptional regulation of transport and metabolism. Methods Enzymol 400:511–30
- EMA. (2012). European medicines agency guideline on the investigation of drug interactions. : EMA
- Fahmi OA, Ripp SL. (2010). Evaluation of models for predicting drug-drug interactions due to induction. Expert Opin Drug Metab Toxicol 6:1399–416
- FDA. (2012). FDA Guidance for Industry 2012: drug interaction studies – study design, data analysis, implications for dosing, and labeling recommendations. Silver Spring (MD): FDA
- Gleeson MP. (2008). Generation of a set of simple, interpretable ADMET rules of thumb. J Med Chem 51:817–34
- Giacomini KM, Huang SM, Tweedie DJ, et al. (2010). Membrane transporters in drug development. Nat Rev Drug Discov 9:215–36
- Jacobsen JK, Jensen B, Skonberg C, et al. (2011). Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes. Eur J Pharm Sci 44:427–36
- Jigorel E, Le Vee M, Boursier-Neyret C, et al. (2006). Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes. Drug Metab Dispos 34:1756–63
- Jorgensen L, Van Beek J, Lund S, et al. (2007). Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes. Eur J Pharm Sci 30:181–9
- Kauffmann HM, Pfannschmidt S, Zoller H, et al. (2002). Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression. Toxicology 171:137–46
- Kern A, Bader A, Pichlmayr R, Sewing KF. (1997). Drug metabolism in hepatocyte sandwich cultures of rats and humans. Biochem Pharmacol 54:761–72
- Marquez B, Van Bambeke F. (2011). ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions. Curr Drug Targets 12:600–20
- McCune JS, Hawke RL, LeCluyse EL, et al. (2000). In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone. Clin Pharmacol Ther 68:356–66
- Pascussi JM, Gerbal-Chaloin S, Drocourt L, et al. (2003). The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors. Biochim Biophys Acta 1619:243–53
- Pelkonen O, Turpeinen M, Hakkola J, et al. (2008). Inhibition and induction of human cytochrome P450 enzymes: current status. Arch Toxicol 82:667–715
- Petrick JS, Klaassen CD. (2007). Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport. Drug Metab Dispos 35:1806–15
- Sinz M, Kim S, Zhu Z, et al. (2006). Evaluation of 170 xenobiotics as transactivators of human Pregnane X Receptor (hPXR) and correlation to known CYP3A4 drug interactions. Curr Drug Metab 7:375–88
- Tirona RG, Kim RB. (2005). Nuclear receptors and drug disposition gene regulation. J Pharm Sci 94:1169–86
- Wilkening S, Bader A. (2003). Influence of culture time on the expression of drug-metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2. J Biochem Mol Toxicol 17:207–13
- Xu C, Li CY, Kong AN. (2005). Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch Pharm Res 28:249–68
- Zhou SF. (2008). Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4. Curr Drug Metab 9:310–22