Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats

References

• Bibi Z. (2008). Role of cytochrome P450 in drug interactions. Nutr Metab 5:27
   Google Scholar
• Bibi Z. (2014). Retraction: role of cytochrome P450 in drug interactions. Nutr Metab 11:11
   Google Scholar
• Blanc PD, Trupin L, Earnest G, et al. (2001). Alternative therapies among adults with a reported diagnosis of asthma or rhinosinusitis: data from a population-based survey. Chest 120:1461–7
   PubMed Web of Science ®Google Scholar
• Bradford MM. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–54
   PubMed Web of Science ®Google Scholar
• Brazier NC, Levine MA. (2003). Drug–herb interaction among commonly used conventional medicines: a compendium for health care professionals. Am J Ther 10:163–9
   PubMedGoogle Scholar
• Danielson PB. (2002). The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans. Curr Drug Metab 3:561–97
   PubMed Web of Science ®Google Scholar
• Diaz D, Fabre I, Daujat M, et al. (1990). Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology 99:737–47
   PubMed Web of Science ®Google Scholar
• Gonzalez FJ. (2005). Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat Res 569:101–10
   PubMed Web of Science ®Google Scholar
• Greenway FL. (2001). The safety and efficacy of pharmaceutical and herbal caffeine and ephedrine use as a weight loss agent. Obes Rev 2:199–211
   PubMedGoogle Scholar
• Gu L, Gonzalez FJ, Kalow W, Tang BK. (1992). Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1. Pharmacogenetics 2:73–7
   PubMedGoogle Scholar
• Ha HR, Chen J, Freiburghaus AU, Follath F. (1995). Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol 39:321–6
   PubMed Web of Science ®Google Scholar
• Hermann R, von Richter O. (2012). Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions. Planta Med 78:1458–77
   PubMed Web of Science ®Google Scholar
• Jonkman JH, Upton RA. (1984). Pharmacokinetic drug interactions with theophylline. Clin Pharmacokinet 9:309–34
   PubMed Web of Science ®Google Scholar
• Josse AR, Da Costa LA, Campos H, El-Sohemy A. (2012). Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption. Am J Clin Nutr 96:665–71
   PubMed Web of Science ®Google Scholar
• Kandel SE, Lampe JN. (2014). Role of protein–protein interactions in cytochrome P450-mediated drug metabolism and toxicity. Chem Res Toxicol 27:1474–86
   PubMed Web of Science ®Google Scholar
• Kelly JP, Kaufman DW, Kelley K, et al. (2005). Recent trends in use of herbal and other natural products. Arch Internal Med 165:281–6
   PubMed Web of Science ®Google Scholar
• Konishi M, Ishii H. (2007). Role of microsomal enzymes in development of alcoholic liver diseases. J Gastroenterol Hepatol 22:S7–10
   PubMed Web of Science ®Google Scholar
• Lee MR. (2011). The history of ephedra (ma-huang). J Roy Coll Phys Edinburgh 41:78–84
   PubMedGoogle Scholar
• Lenz TL, Hamilton WR. (2004). Supplemental products used for weight loss. J Am Pharm Assoc 44:59–67; quiz -8
   Google Scholar
• Li J, Wei DQ, Wang JF, et al. (2012). Molecular dynamics simulations of CYP2E1. Med Chem 8:208–21
   PubMed Web of Science ®Google Scholar
• Lieber CS. (1997). Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 77:517–44
   PubMed Web of Science ®Google Scholar
• Lu Y, Cederbaum AI. (2008). CYP2E1 and oxidative liver injury by alcohol. Free Rad Biol Med 44:723–38
   PubMed Web of Science ®Google Scholar
• Mukherjee PK, Ponnusankar S, Pandit S, et al. (2011). Botanicals as medicinal food and their effects on drug metabolizing enzymes. Food Chem Toxicol 49:3142–53
   PubMed Web of Science ®Google Scholar
• Nakao M, Muramoto Y, Hisadome M, et al. (2007). The effect of Shoseiryuto, a traditional Japanese medicine, on cytochrome P450s, N-acetyltransferase 2 and xanthine oxidase, in extensive or intermediate metabolizers of CYP2D6. Eur J Clin Pharmacol 63:345–53
   PubMed Web of Science ®Google Scholar
• Obach RS. (2009). Predicting drug–drug interactions from in vitro drug metabolism data: challenges and recent advances. Curr Opin Drug Discov Dev 12:81–9
   PubMed Web of Science ®Google Scholar
• Ogilvie RI. (1978). Clinical pharmacokinetics of theophylline. Clin Pharmacokinet 3:267–93
   PubMed Web of Science ®Google Scholar
• Ohnishi A, Kato M, Kojima J, et al. (2003). Differential pharmacokinetics of theophylline in elderly patients. Drugs Aging 20:71–84
   PubMed Web of Science ®Google Scholar
• Paolini M, Barillari J, Broccoli M, et al. (1999). Effect of liquorice and glycyrrhizin on rat liver carcinogen metabolizing enzymes. Cancer Lett 145:35–42
   PubMed Web of Science ®Google Scholar
• Paolini M, Pozzetti L, Sapone A, Cantelli-Forti G. (1998). Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases. Life Sci 62:571–82
   PubMed Web of Science ®Google Scholar
• Pekthong D, Blanchard N, Abadie C, et al. (2009). Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures. Chem Biol Interact 179:247–55
   PubMed Web of Science ®Google Scholar
• Shekelle PG, Hardy ML, Morton SC, et al. (2003). Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis. JAMA 289:1537–45
   PubMed Web of Science ®Google Scholar
• Tang J, Zhou X, Ji H, et al. (2012). Effects of ephedra water decoction and cough tablets containing ephedra and liquorice on CYP1A2 and the pharmacokinetics of theophylline in rats. Phytother Res 26:470–4
   PubMed Web of Science ®Google Scholar
• VandenBrink BM, Isoherranen N. (2010). The role of metabolites in predicting drug–drug interactions: focus on irreversible cytochrome P450 inhibition. Curr Opin Drug Discov Dev 13:66–77
   PubMed Web of Science ®Google Scholar
• Vistisen K, Loft S, Poulsen HE. (1991). Cytochrome P450 IA2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise. Adv Exp Med Biol 283:407–11
   PubMedGoogle Scholar
• Yan Z, Caldwell GW. (2012). The current status of time dependent CYP inhibition assay and in silico drug–drug interaction predictions. Curr Top Med Chem 12:1291–7
   PubMed Web of Science ®Google Scholar
• Zhang ZY, Kaminsky LS. (1995). Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation. Biochem Pharmacol 50:205–11
   PubMed Web of Science ®Google Scholar