Pharmacokinetic comparisons of Paeoniflorin and Paeoniflorin-6'O-benzene sulfonate in rats via different routes of administration

References

• Binkhathlan Z, Lavasanifar A. (2013). P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: current status and future perspectives. Curr Cancer Drug Targets 13:326–46
   PubMed Web of Science ®Google Scholar
• Chang Y, Wei W, Zhang L, Xu HM. (2009). Effects and mechanisms of total glucosides of paeony on synoviocytes activities in rat collagen-induced arthritis. J Ethnopharmacol 121:43–8
   PubMed Web of Science ®Google Scholar
• Chang Y, Zhang L, Wang C, et al (2011). Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP4 receptor expression. J Ethnopharmacol 137:1275–82
   PubMed Web of Science ®Google Scholar
• Chan K, Liu ZQ, Jiang ZH, et al (2006). The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model. J Ethnopharmacol 103:425–32
   PubMed Web of Science ®Google Scholar
• Chen JY, Wu HX, Chen Y, et al (2012). Paeoniflorin inhibits proliferation of fibroblast-like synoviocytes through suppressing G-protein-coupled receptor kinase 2. Planta Med 78:665–71
   PubMed Web of Science ®Google Scholar
• Cheng Y, Peng C, Wen F, Zhang H. (2010). Pharmacokinetic comparisons of typical constituents in white peony root and sulfur fumigated white peony root after oral administration to mice. J Ethnopharmacol 129:167–73
   PubMed Web of Science ®Google Scholar
• He F, Mou JL, Zhang ZR, et al (2013). Simultaneous determination of hydroxyl-paeoniflorin, albiflorin and benzoyl-paeoniflorin in rat plasma by UPLC-MS/MS. Chin Tradit Pat Med 35:2617–21
   Google Scholar
• He JX, Akao T, Tani T. (2003). Influence of co-administered antibiotics on the pharmacokinetic fate in rats of paeoniflorin and its active metabolite paeonimetabolin-I from Shaoyao-Gancao-tang. J Pharm Pharmacol 55:313–21
   PubMed Web of Science ®Google Scholar
• Jia XY, Chang Y, Sun XJ, et al (2014). Total glucosides of paeony inhibit the proliferation of fibroblast-like synoviocytes through the regulation of G proteins in rats with collagen-induced arthritis. - arthritis. Int Immunopharmacol 18:1–6
   PubMed Web of Science ®Google Scholar
• Kim SH, Lee MK, Lee KY, et al (2009). Chemical constituents isolated from Paeonia lactiflora roots and their neuroprotective activity against oxidative stress in vitro. J Enzyme Inhib Med Chem 24:1138–40
   PubMed Web of Science ®Google Scholar
• König J, Müller F, Fromm MF. (2013). Transporters and drug-drug interactions: important determinants of drug disposition and effects. Pharmacol Rev 65:944–66
   PubMed Web of Science ®Google Scholar
• Li DF, Yin RL, Lv YP, et al (2011). Determination of n-octanol/water partition coefficients of paeoniflorin and the effect of pH on it. Pharm Clin Chin Mat Med 2:21–3
   Google Scholar
• Li PP, Liu DD, Liu YJ, et al (2012). BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin. J Ethnopharmacol 141:290–300
   PubMed Web of Science ®Google Scholar
• Li Y, Sheng K, Chen J, et al (2015). Regulation of PGE2 signaling pathways and TNF-alpha signaling pathways on the function of bone marrow-derived dendritic cells and the effects of CP-25. Eur J Pharmacol 769:8–21
   PubMed Web of Science ®Google Scholar
• Liu ZQ, Jiang ZH, Liu L, Hu M. (2006). Mechanisms responsible for poor oral bioavailability of paeoniflorin: role of intestinal disposition and interactions with sinomenine. Pharm Res 23:2768–80
   PubMed Web of Science ®Google Scholar
• Min WQ, Wei Q, Li HY, et al (2005). A clinical study of total glucosides paeony in the treatment of rheumatoid arthritis: a multi-center trial. Chin J Rheumatol 9:487–91
   Google Scholar
• Moitessier N, Englebienne P, Chapleur Y. (2005). Directing-protecting groups for carbohydrates. Design, conformational study, synthesis and application to regioselective functionalization. Tetrahedron 61:6839–53
   Web of Science ®Google Scholar
• Pate M, Mandava NK, Pal D, Mitra AK. (2014). Amino acid prodrug of quinidine: an approach to circumvent P-glycoprotein mediated cellular efflux. Int J Pharm 464:196–204
   PubMed Web of Science ®Google Scholar
• Takeda S, Isono T, Wakui Y, et al (1995). Absorption and excretion of paeoniflorin in rats. J Pharm Pharmacol 47:1036–40
   PubMed Web of Science ®Google Scholar
• Wang C, Yuan J, Wu HX, et al (2013). Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis by regulating the balance between inflammatory and anti-inflammatory cytokines. Inflamm Res 62:1035–44
   PubMed Web of Science ®Google Scholar
• Wang C, Yuan J, Yang ZY, et al (2012). Pharmacokinetics of paeoniflorin microemulsion after repeated dosing in rats with adjuvant arthritis. Pharmazie 67:997–1001
   PubMed Web of Science ®Google Scholar
• Wang C, Yuan J, Wei W. (2014). Study on paeoniflorin-6'O-benzene sulfonate’s physicochemical property. Acta Univ Med an Hui 49:202–5
   Google Scholar
• Wang QT, Zhang LL, Wu HX, Wei W. (2011). The expression change of β-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony. J Ethnopharmacol 133:511–6
   PubMed Web of Science ®Google Scholar
• Wei W. (2012). The preparation method and applications of a kind of paeoniflorin aromatic ester’s derivatives: China. CN102603827B. 2012-02-10. http://epub.sipo.gov.cn/index.action
   Google Scholar
• Yang XD, Wang C, Zhou P, et al (2015). Absorption characteristic of paeoniflorin-6'-O-benzene sulfonate (CP-25) in in situ single-pass intestinal perfusion in rats. Xenobiotica. [Epub ahead of print]. DOI: 10.3109/00498254.2015.1121553
   Web of Science ®Google Scholar
• Yang XW, Guo J, Xu W. (2013). Absorption and transport characteristic of paeoniflorin and its derivatives in model of Caco-2 cell monolayers. Chin Tradit Herb Drugs 44:2097–104
   Google Scholar
• Ye L, Yang X, Yang Z, et al (2013). The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells. Toxicol Lett 216:86–99
   PubMed Web of Science ®Google Scholar
• Yen PH, Kiem PV, Nhiem NX, et al (2007). A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells. Arch Pharm Res 30:1179–85
   PubMed Web of Science ®Google Scholar
• Yoshida K, Furuta T, Kawabata T. (2010). Perfectly regioselective acylation of a cardiac glycoside, digitoxin, via catalytic amplification of the intrinsic reactivity. Tetrahedron Letters 51:4830–2
   Web of Science ®Google Scholar