Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 12
197
Views
8
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

Sodium tanshinone IIA sulfonate and its interactions with human CYP450s

, , , , , , , , & show all
Pages 1085-1092 | Received 02 Jan 2016, Accepted 05 Feb 2016, Published online: 02 Mar 2016

References

  • Bourrie M, Meunier V, Berger Y, et al. (1996). Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes. J Pharmacol Exp Ther 277:321–32
  • Chen S, Zhao X, Li Y, et al. (2013). Impurities preparation of sodium tanshinone IIA sulfonate by high-speed counter-current chromatography and identification by liquid chromatography/multistage tandem mass spectrometry. J Chromatogr A 1288:28–34
  • Chen W, Tang F, Xie B, et al. (2012). Amelioration of atherosclerosis by tanshinone IIA in hyperlipidemic rabbits through attenuation of oxidative stress. Eur J Pharmacol 674:359–64
  • Chen Y, Tu JH, He YJ, et al. (2009). Effect of sodium tanshinone IIA sulfonate on the activity of CYP1A2 in healthy volunteers. Xenobiotica 39:508–13
  • Ching MS, Blake CL, Ghabrial H, et al. (1995). Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine, and its metabolites. Biochem Pharmacol 50: 833-37
  • Dong X, Dong J, Zhang R, et al. (2009). Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response. Cancer Biother Radiopharm 24:681–7
  • Gebhardt AC, Lucas D, Menez JF, et al. (1997). Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans. Hepatology 26:957–961
  • Gervasini G, Garcia M, Macias RM, et al. (2012). Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation. Transpl Int 25:471–80
  • Hao H, Wang G, Cui N, et al. (2007). Determination of sodium tanshinone IIA sulfonate in plasma by liquid chromatography-electrospray ionisation-tandem mass spectrometry. Biomed Chromatogr 21:1172–9
  • Jeong S, Nguyen PD, Desta Z. (2009). Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A. Antimicrob Agent Chemother 53:541–51
  • Kong WM, Chik Z, Ramachandra M, et al. (2011). Evaluation of the effects of Mitragyna speciosa alkaloid extract on cytochrome P450 enzymes using a high throughput assay. Molecules 16:7344–56
  • Li X, Wang K, Wei W, et al. (2013). In vitro metabolism of brucine by human liver microsomes and its interactions with CYP substrates. Chem Biol Interact 204:140–3
  • Liu F, Yu G, Wang G, et al. (2012). An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer. PLoS One 7:e42138
  • Liu HX, Hu Y, Liu Y, et al. (2009). Hydroxylation of tanshinone IIa in human liver microsomes is specifically catalysed by cytochrome P4502A6. Xenobiotica 39:382–90
  • Liu JQ, Lee TF, Miedzyblocki M, et al. (2011). Effects of tanshinone IIA, a major component of Salvia miltiorrhiza, on platelet aggregation in healthy newborn piglets. J Ethnopharmacol 137:44–9
  • Maione F, de Feo V, Caiazzo E, et al. (2014). Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway. J Ethnopharmacol 155:1236-42
  • Mao S, Jin H, Bi Y, et al. (2007). Ion-pair reversed-phase HPLC method for determination of sodium tanshinone IIA sulfonate in biological samples and its pharmacokinetics and biodistribution in mice. Chem Pharm Bull 55:753–6
  • Murayama N, Nakamura T, Saeki M, et al. (2002). CYP3A4 gene polymorphisms influence testosterone 6beta-hydroxylation. Drug Metab Pharmacokinet 17:150–6
  • Qin CZ, Ren X, Tan ZR, et al. (2014). A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry. Biomed Chromatogr 28:197–203
  • Ring BJ, Binkley SN, Vandenbranden M, et al. (1996). In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A. Br J Clin Pharmacol 41:181–6
  • Sun N, Cong XM, Jiang JB, et al. (2014a). Sodium tanshinone IIA sulfonate inhibits the meq, ul49 and VP22 expression of Marek’s disease virus. Antiviral Ther 19:793–8
  • Sun N, Li E, Wang Z, et al. (2014b). Sodium tanshinone IIA sulfonate inhibits porcine reproductive and respiratory syndrome virus via suppressing N gene expression and blocking virus-induced apoptosis. Antiviral Ther 19:89–95
  • Sun N, Zhao X, Bai XY, et al. (2012). Anti-PRRSV effect and mechanism of sodium tanshinone IIA sulfonate in vitro. J Asian Nat Prod Res 14:721–8
  • Taavitsainen P, Juvonen R, Pelkonen O. (2001). In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene. Drug Metab Dispos 29:217–22
  • Ueng YF, Kuo YH, Peng HC, et al. (2003). Diterpene quinone tanshinone IIA selectively inhibits mouse and human cytochrome p4501A2. Xenobiotica 33:603–13
  • Ueng YF, Kuo YH, Wang SY, et al. (2004). Induction of CYP1A by a diterpene quinone tanshinone IIA isolated from a medicinal herb Salvia miltiorrhiza in C57BL/6J but not in DBA/2J mice. Life Sci 74:885–96
  • Wang P, Zhou S, Xu L, et al. (2013). Hydrogen peroxide-mediated oxidative stress and collagen synthesis in cardiac fibroblasts: blockade by tanshinone IIA. J Ethnopharmacol 145:152–61
  • Wang X, Cheung CM, Lee WY, et al. (2010). Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro. Phytomedicine 17:868–75
  • Wei B, Li WW, Ji J, et al. (2014). The cardioprotective effect of sodium tanshinone IIA sulfonate and the optimizing of therapeutic time window in myocardial ischemia/reperfusion injury in rats. Atherosclerosis 235:318–27
  • Xu C, Desta Z. (2013). In vitro analysis and quantitative prediction of efavirenz inhibition of eight cytochrome P450 (CYP) enzymes: major effects on CYPs 2B6, 2C8, 2C9 and 2C19. Drug Metab Pharmacokinet 28:362–71
  • Yang L, Zou X, Liang Q, et al. (2007). Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway. Exp Mol Med 39:65–73
  • Yang R, Liu A, Ma X, et al. (2008). Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation. J Cardiovasc Pharmacol 51:396–401
  • Yang XF, Wang NP, Lu WH, Zeng FD. (2003). Effects of Ginkgo biloba extract and tanshinone on cytochrome P-450 isozymes and glutathione transferase in rats. Acta Pharmacol Sin 24:1033–8
  • Yu H, Subedi RK, Nepal PR, et al. (2012). Enhancement of solubility and dissolution rate of cryptotanshinone, tanshinone I and tanshinone IIA extracted from Salvia miltiorrhiza. Arch Pharm Res 35:1457–64
  • Zhou LP, Yao F, Luan H, et al. (2013). CYP3A4*1B polymorphism and cancer risk: a HuGE review and meta-analysis. Tum Biol 34:649–60
  • Zhou S, Gao Y, Jiang W, et al. (2003). Interactions of herbs with cytochrome P450. Drug Metab Rev 35:35–98

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.