Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl- 4H-s-triazolo [4,3-a] [1,4] benzodiazepine, triazolam, a new central depressant. I. Absorption, distribution and excretion in rats, dogs and monkeys

H. Kitagawa Department of Biochemical Pharmacology, Faculty of Pharmaceutical Sciences, Chiba University, 1-33, Yayoicho, Chiba, 280, Japan

Y. Esumi Tokai Laboratories, Daiichi Pure Chemicals Co., Ltd., Tokaimura, Nakagun, Ibaragi, 319-11, Japan

S. Kurosawa Tokai Laboratories, Daiichi Pure Chemicals Co., Ltd., Tokaimura, Nakagun, Ibaragi, 319-11, Japan

S. Sekine Tokai Laboratories, Daiichi Pure Chemicals Co., Ltd., Tokaimura, Nakagun, Ibaragi, 319-11, Japan

T. Yokoshima Tokai Laboratories, Daiichi Pure Chemicals Co., Ltd., Tokaimura, Nakagun, Ibaragi, 319-11, Japan

References