Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 9
36
Views
39
CrossRef citations to date
0
Altmetric
Original Article

Menadione (2-methyl-1,4-naphthoquinone)-induced Ca2+ release from rat-liver mitochondria is caused by NAD(P)H oxidation

, &
Pages 873-882 | Received 24 Jan 1986, Published online: 30 Sep 2009

References

  • Åkerman K. E. O., Nicholls D. G. Physiological and bioenergetic aspects of mitochondrial calcium transport. Reviews of Physiology, Biochemistry and Pharmacoloty 1983; 95: 149–201
  • Azzi A., Montecucco C., Richter C. The use of acetylated ferricytochrome c for the detection of superoxide radicals produced in biological membranes. Biochemical and Biophysical Research Communications 1975; 65: 597–607
  • Beatrice M. C., Stiers D. L., Pfeiffer D. R. The role of glutathione in the retention of Ca2+ by liver mitochondria. The Journal of Biological Chemistry 1984; 259: 1279–1287
  • Bellomo G., Jeweli S. A., Orrenius S. The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium. The Journal of Biological Chemistry 1982; 257: 11558–11562
  • Bellomo G., Martino A., Richelmi P., Moore G. A., Jewell S. A., Orrenius S. Pyridine-nucleotide oxidation, Ca2+ cycling and membrane damage during tert-butyl hydro-peroxide metabolism by rat-liver mitochondria. European Journal of Biochemistry 1984; 140: 1–6
  • Calcium and Cell Function, Vol. 2, W. Y. Cheung. Academic Press, New York 1982
  • Conover T. E., Ernster L. DT Diaphorase IV. Coupling of extramitochondrial reduced pyridine nucleotide oxidation to mitochondrial respiratory chain. Biochemica et Biophysica Acta 1963; 67: 268–280
  • Di Guiseppi J., Fridovich I. The toxicology of molecular-oxygen. CRC Critical Reviews in Toxicology 1984; 12: 315–342
  • Di Monte D., Bellomo G., Thor H., Nicotera P., Orrenius S. Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis. Archives of Biochemistry and Biophysics 1984a; 235: 343–350
  • Di Monte D., Ross D., Bellomo G., Eklöw L., Orrenius S. Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Archives of Biochemistry and Biophysics 1984b; 235: 334–342
  • Eklöw L., Moldéus P., Orrenius S. Oxidation of glutathione during hydroperoxide metabolism: a study using isolated hepatocytes and the glutathione reductase inhibitor 1,3-bis(2-chloroethyl)-1-nitroso-urea. European Journal of Biochemistry 1984; 138: 459–463
  • Ernster L., Ljunggren M., Danielson L. Purification and some properties of a highly dicumarol-sensitive liver diaphorase. Biochemical and Biophysical Research Communications 1960; 1960: 88–92
  • Hofstetter W., Mühlebach T., Lötscher H. R., Winterhalter K. H., Richter C. ATP prevents both hydroperoxide-hydrolysis of pyridine-nucleotides and release of calcium in rat-liver mitochondria. European Journal of Biochemistry 1981; 117: 361–367
  • Iyanagi T., Yamazaki I. One-electron-transfer reactions in biochemical systems: V. Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase). Biochemica et Biophysica Acta 1970; 216: 282–294
  • Jewell S. A., Bellomo G., Thor H., Orrenius S., Smith M. T. Bleb formation in hepatocytes during drug metabolism is caused by disturbance in thiol and calcium ion homeostasis. Science 1982; 217: 1257–1259
  • Lehninger A. L., Vercesi A., Bababunni E. A. Regulation of Ca2+ release from mitochondria by the oxidation-reduction state of pyridine nucleotides. Proceedings of the National Academy of Science of the United States of America 1978; 75: 1690–1694
  • Lind C., Hochstein P., Ernster L. DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation. Archives of Biochemistry and Biophysics 1982; 216: 178–185
  • Lötscher H. R., Winterhalter K. H., Carafoli E., Richter C. Hydroperoxides can modulate the redox state of pyridine nucleotides and the calcium balance in rat liver mitochondria. Proceedings of the National Academy of Science of the United States of America 1979; 76: 4340–4344
  • Lötscher H. R., Winterhalter K. H., Carafoli E., Richter C. Hydroperoxide-induced loss of pyridine nucleotides and release of calcium from rat liver mitochondria. The Journal of Biological Chemistry 1980; 255: 9325–9330
  • Lowry O. H., Rosenbrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. The Journal of Biological Chemistry 1951; 193: 265–275
  • Moore G. A., Jewell S. A., Bellomo G., Orrenius S. On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria. FEBS Letters 1983; 153: 289–292
  • Nicholls D., Åkerman K. Mitochondrial calcium transport. Biochimica et Biophysica Acta 1982; 683: 57–88
  • Paglia D. E., Valentine W. N. Studies on quantitative and qualitative characterization of erythrocyte glutathione peroxidase. Journal of Laboratory and Clinical Medicine 1967; 70: 158–169
  • Patel K. B., Willson R. L. Semiquinone free-radicals and oxygen pulse-radiolysis study of one electron-transfer equilibria. Journal of the Chemical Society. Faraday Transactions 1 1973; 69: 814–825
  • Reed D. J., Babson J. R., Beatty P. W., Brodie A. E., Potter D. W. High-performance liquid-chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Analytical Biochemistry 1980; 106: 55–62
  • Shears S. B., Kirk C. J. Characterization of a rapid cellular-fractionation technique for hepatocytes. Application in the measurement of mitochondrial membrane potential in situ. The Biochemical Journal 1984; 219: 375–382
  • Thor H., Smith M. T., Hartzell P., Bellomo G., Jewell S. A., Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes: a study of the implication of oxidative stress in intact cells. The Journal of Biological Chemistry 1982; 257: 12419–12425
  • Wefers H., Sies H. Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: relation to glutathione and NAD(P)H: quinone reductase (DT-diaphorase) activity. Archives of Biochemistry and Biophysics 1983; 224: 568–578
  • Williamson J. R., Cooper R. H., Hoek J. B. Role of calcium in the hormonal regulation of liver metabolism. Biochimica et Biophysica Acta 1981; 639: 243–295

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.