Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 12
9
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The metabolic fate of camazepam in rats

, , &
Pages 1079-1089 | Received 12 Apr 1985, Published online: 30 Sep 2009

References

  • Bell S. C., Childress S. J. A rearrangement of 5-aryl-1,3-dihydro-2H-1,4-benzodiazepine-2-one-4-oxides. Journal of Organic Chemistry 1962; 27: 1691–1695
  • Beyer K. H., Sadee W. Spectrometrische bestimmung von 5-phenyl-1,4-benzodiazepine-derivaten und untersuchungen über den metabolismus des nitrazepams. Arzneimittel Forschung 1969; 19: 1929–1931
  • Cesa-Bianchi M., Ghirardi P., Ravaccia F. A preliminary double-blind study with, SB 5833 (camazepam), a new benzodiazepine derivative. Arzneimittel Forschung 1974; 24: 2032–2035
  • Chupp J. P., Speziale A. J. An n.m.r. study of hydroxymethylation of some substituted amides. Journal of Organic Chemistry 1963; 28: 2592–2595
  • Ebel S., Schütz H. Untersuchungen zum nachweis von clonazepam und seinen hauptmataboliten. Arzneimittel Forschung 1977; 27: 325–337
  • Ferrini R., Miragoli G., Taccardi. Neuro-pharmacological studies on SB 5833, a new psychotherapeutic agent of the benzodiazepine class. Arzneimittel Forschung 1974; 24: 2029–2035
  • Galli G. Camazepam (SB/5833) in preparation for endoscopy inspection: open and double-blind study versus diazepam. Current Therapeutic Research 1976; 19: 316–319
  • Koechlin B. A., Schwartz M. A., Krol W., Oberhansli J. The metabolic fate of 14C-labeled chlordiazpoxide in man, in the dog and in the rat. Journal of Pharmacology and Experimental Therapeutics 1965; 148: 399–411
  • Koga D., Imoto T., Nakamura Y., Fujikawa K., Yanagishita K. Analysis of the reaction between formaldehyde and amide. Agricultural and Biological Chemistry 1978; 42(6)1147–1156
  • Marcucci F., Mussini E., Cotellessa L., Ghirardi P., Parenti M., Riva R., Salva P. Distribution of camazepam in rats and mice. Journal of Pharmaceutical Sciences 1978; 67: 1470–1471
  • Mortimore G. E., Tietze F. Studies on the mechanism of capture and degradation of insulin-I131 by the cyclically perfused rat liver. Annals New York Academy of Sciences 1959; 82: 329–337
  • Schillings R. T., Shrader H. W., Ruelius H. W. Metabolismus und pharmakokinetik des neuen psychopharmakons 7-chlor-2,3-dihydro-1-methyl-5-phenyl-1 H-1,4-benzodiazepine (Ro 5–4556) beim menschen. Arzneimittel Forschung 1968; 18: 1545–1556
  • Schütz H. Analytik und biotransformation von camazepam (Albego). einem neuen traquilizer zus der reihe der 1,4-benzodiazepine. Das Ärzliche Laboratorium 1979; 25: 75–78
  • Sisenwine S. F., Tio C. O., Shrader S. R., Ruelius H. W. The biotransformation of oxazepam (7-chloro-1,3-dihydro-3-hydroxy-5-phenyI-2H-1,4-benzodiazepine-2-one) in man, miniature swine and rat. Arzneimittel Forschung 1972; 22: 682–687
  • Sternbach L. H., Kaiser S., Reeder E. Quinozolin 3-oxide structure of compounds previously described in the literature as 3,1,4-benzodiazepine. Journal of American Chemistry Society 1960; 82: 475–480
  • Voltz M., Christ O., Kellner H. W., Kuch H., Fehlhaber H. W., Gantz D., Hajdu P., Cavagna F. Kinetics and metabolism of clabazam in animals and man. British Journal of Clinical Pharmacology 1979; 7: 41S–50S
  • Walkeinstein S. S., Wiser R., Gudmundsen C. H., Kimmel H. B., Corradino R. A. Absorption, metabolism and excretion of oxazepam and its succinate half-ester. Journal of Pharmaceutical Sciences 1964; 53: 1181–1186

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.