Application of isolated hepatocytes to studies of drug metabolism in large food animals

References

• Agius L., Battersby C., Alberti K. G. M. M. Monolayer culture of parenchymal rat hepatocytes on collagen-coated micro-carriers. A hepatocyte system for long and short-term metabolic studies. In Vitro. Cellular and Developmental Biology 1985; 21: 254–259
   Google Scholar
• Akhtar M. H. Metabolism of deltamethrin by cow and chicken liver enzyme preparations. Journal of Agricultural and Food Chemistry 1984; 32: 258–262
   Web of Science ®Google Scholar
• Alary J. G., Guay P., Brodeur J. Effect of phenobarbital pretreatment on the metabolism of DDT in the rat and the bovine. Toxicology and Applied Pharmacology 1971; 18: 457–468
   PubMed Web of Science ®Google Scholar
• Billings R. E., McMahon R. E., Ashmore J., Wagle S. R. The metabolism of drugs in isolated rat hepatocytes: a comparison with in vivo drug metabolism and drug metabolism in subcellular liver fractions. Drug Metabolism and Disposition 1977; 5: 518–526
   PubMed Web of Science ®Google Scholar
• Bissel D. M., Hammaker L. E., Meyer U. A. Parenchymal cells from adult liver in non-proliferating monolayer culture. Journal of Cell Biology 1973; 59: 722–734
   PubMedGoogle Scholar
• Brooks G. T. The metabolism of dieneorganochlorine (cyclodiene) insecticides. Residue Reviews 1969; 27: 81–138
   PubMedGoogle Scholar
• Caldwell J., Hutt A. J. Prediction of metabolic pathways-current status and future prospects. Foreign Compound Metabolism, J. Caldwell, G. D. Paulson. Taylor & Francis, London 1984; 101–108
   Google Scholar
• Cesarone C. F., Fugassa E., Gallo G., Voci A., Orunesu M. Collagenase perfusion of rat liver induces DNA damage and DNA repair in hepatocytes. Mutagenesis Research 1984; 141: 113–116
   PubMedGoogle Scholar
• Chin B. H., Elderidge J. M., Anderson J. H., Sullivan L. J. Carbaryl metabolism in the rat. A comparison of in vivo, in vitro (tissue explant), and liver perfusion technique. Journal of Agricultural and Food Chemistry 1979; 27: 716–720
   PubMedGoogle Scholar
• Chin B. H., Elderidge J. M., Sullivan L. J. Metabolism of carbaryl by selected human tissues using an organ-maintenance technique. Clinical Toxicology 1974; 7: 37–56
   PubMed Web of Science ®Google Scholar
• Cinti D. L., Ritchie A., Schenkman I. B. Hepatic organelle interaction. II. Effect of tricarboxylic acid cycle intermediates on N-demethylation and hydroxylation reactions in rat liver. Molecular Pharmacology 1971; 8: 339–344
   Google Scholar
• Cook R. M., Wilson K. A. Metabolism of xenobiotics in ruminants. Phenobarbital induction of liver microsomal nitrogen demethylase. Journal of Agricultural and Food Chemistry 1970; 18: 441–442
   PubMed Web of Science ®Google Scholar
• Delatour P. Evaluation of drug residues in animal tissues. Veterinary Pharmacology and Toxicology, Y. Ruskebusch, P. Toutain, G. D. Koritz. AVI Pub. Co., Inc., Westport, CNUSA 1983; 659–670
   Google Scholar
• Dorough H. W. Classification of radioactive pesticide residues in food-producing animals. Journal of Environmental Pathology and Toxicology 1980; 3: 11–19
   PubMedGoogle Scholar
• Douch P. G. C. The metabolism of some thioureidobenzene fungicides in mice and sheep. Xenobiotica 1974; 4: 457–475
   PubMedGoogle Scholar
• Drochmans P., Wanon J -C., Mosselmans R. Isolation and subfractionation on ficoll gradients of adult rat hepatocytes. Size, morphology, and biochemical characteristics of cell fractions. Journal of Cell Biology 1975; 66: 1–22
   PubMed Web of Science ®Google Scholar
• Dutton G. J. Glucuronide synthesis in foetal liver and other tissues. Biochemistry Journal 1959; 71: 141–148
   PubMed Web of Science ®Google Scholar
• Engelmann G. L., Richardson A. G., Fierer J. A. Maintenance and induction of cytochrome P-450 in cultured rat hepatocytes. Archives of Biochemistry and Biophysics 1985; 238: 359–367
   PubMed Web of Science ®Google Scholar
• Brickson R. R., Holtzman J. L. Kinetic studies on the metabolism of ethylmorphine by isolated hepatocytes from adult rats. Biochemical Pharmacology 1976; 25: 1501–1506
   PubMedGoogle Scholar
• Evarts R. P., Marsden E., Thorgeirsson S. Regulation of heme metabolism and cytochrome P-450 levels in primary culture of rat hepatocytes in a defined medium. Biochemical Pharmacology 1984; 33: 565–569
   PubMedGoogle Scholar
• Forsell J. H., Jesse B. W., Shull L. R. A technique for isolation of bovine hepatocytes. Journal of Animal Science 1985; 60: 1597–1609
   PubMedGoogle Scholar
• Fries G. F. The PBB episode in Michigan: an overall appraisal. CRC Critical Reviews in Toxicology 1985; 16: 105–156
   Web of Science ®Google Scholar
• Fries G. F., Marrow G. S., Gordon C. H. Long-term studies of residue retention and excretion by cows fed a polychlorinated biphenyl (Aroclor 1254). Journal of Agricultural and Food Chemistry 1973; 21: 117–121
   PubMed Web of Science ®Google Scholar
• Fry J. R., Bridges J. W. The metabolism of xenobiotics in cell suspensions and cell cultures. Progress in Drug Metabolism, J. W. Bridges, L. F. Chasseud. John Wiley and Sons, Chichester 1977; 71–118
   Google Scholar
• Fry J. R., Bridges J. W. Use of primary hepatocytes in biochemical toxicology. Reviews in Biochemical Toxicology 1979; 1: 101–247
   Google Scholar
• Goldfarb S., Barber T. A., Pariza M. W., Pugh T. D. Lipid synthesis and ultrastructure of adult rat hepatocytes during their first twenty-four hours in culture. Experimental Cell Research 1978; 117: 39–46
   PubMedGoogle Scholar
• Grisham J. W. Use of hepatic cell cultures to detect and evaluate the mechanisms of action of toxic chemicals. International Reviews in Experimental Pathology 1979; 20: 123–209
   PubMedGoogle Scholar
• Gutenmann W. H., Lisk D. J. Metabolic studies with chloroneb fungicide in a lactating cow. Journal of Agricultural and Food Chemistry 1969; 17: 1008–1010
   PubMedGoogle Scholar
• Gutenmann W. H., Lisk D. J. Metabolism and excretion of bromacil in milk of dairy cows. Journal of Agricultural and Food Chemistry 1970; 18: 128–129
   PubMedGoogle Scholar
• Gutenmann W. H., St John L. E., Lisk D. J. Metabolic studies with gardona insecticide in the dairy cow. Journal of Agricultural and Food Chemistry 1971; 19: 1259–1260
   PubMed Web of Science ®Google Scholar
• Gutenmann W. H., Lisk D. J. Metabolism of TOK herbicide in the dairy cow. Journal of Dairy Science 1976; 50: 1516–1518
   Google Scholar
• Hayes J. R., Polan C. E., Campbell T. C. Bovine liver metabolism and tissue distribution of aflatoxin B1. Journal of Agricultural and Food Chemistry 1977; 25: 1189–1193
   PubMedGoogle Scholar
• Hirono I. Natural carcinogens of plant origin. CRC Critical Reviews in Toxicology 1981; 8: 235–277
   Web of Science ®Google Scholar
• Huber T. L., Horn G. W., Beadle R. E. Liver and gastrointestinal metabolism of diethylstilbestrol in sheep. Journal of Animal Science 1972; 34: 786–790
   PubMed Web of Science ®Google Scholar
• Kao J., Jones C. A., Fry J. R., Bridges J. W. Species differences in the metabolism of benzoic acid by isolated hepatocytes and kidney tubule fragments. Life Sciences 1978; 23: 1221–1228
   PubMedGoogle Scholar
• Keeler R. F. Toxins in plants. Safety of Foods, H. D. Graham. AVI Pub. Co., Inc., Westport, CNUSA 1980; 593–624
   Google Scholar
• Kletzein R. F., Pariza M. W., Becher W. W., Potter V. R., Richard F. R. Induction of amino acid transport in primary cultures of adult rat liver parenchymal cells by insulin. Journal of Biological Chemistry 1976; 251: 3014–3020
   PubMedGoogle Scholar
• Krebs H. A. Rate control of the tricarboxylic acid cycle. Advances in Enzyme Regulation 1970; 8: 335–353
   PubMedGoogle Scholar
• Laishes B. A., Williams G. M. Conditions affecting primary cell cultures of functional adult rat hepatocytes. I. The effect of insulin. In Vitro 1976a; 12: 521–532
   PubMedGoogle Scholar
• Laishes B. A., Williams G. M. Conditions affecting primary cell cultures of functional adult rat hepatocytes. Ii. Dexamethasone enhanced longevity and maintenance of morphology 1976b; 12: 821–832, In Vitro
   Google Scholar
• Lake B. G., Paine A. J. The effect of hepatocyte culture conditions on cytochrome P-450 linked drug metabolizing enzymes. Biochemical Pharmacology 1982; 31: 2141–2144
   PubMed Web of Science ®Google Scholar
• Maiorino R. M., Whiting F. M., Brown W. H., Reid B. L., Stull J. W. Metabolism of toxaphene by the isolated perfused bovine liver. Archives of Environmental Contamination and Toxicology 1984; 13: 565–571
   PubMedGoogle Scholar
• Matsumura F., Madhukar B. V. Exposure to insecticides. Pharmacology and Therapeutics 1980; 9: 27–49
   PubMedGoogle Scholar
• Menzer R. E. Techniques for studying the metabolism of xenobiotics by intact animal cells, tissues, and organs in vitro. Xenobiotic Metabolism: In Vitro Methods, G. D. Paulson, D. S. Frear, E. P. Marks. American Chemical Society, Washington, DC 1979; 131–148, no. 97
   Google Scholar
• Metcalf R. L., Lu P. Y., Bowlus S. Degradation and environmental fate of 1-(2,6-difluorobenzoyl)-3-(4-chlorophenyl) urea. Journal of Agricultural and Food Chemistry 1975; 23: 359–364
   PubMedGoogle Scholar
• Moldeus P., Jernstrom B., Dawson J. The use of freshly isolated or cultured hepatocytes in studies of the metabolism of polycyclic aromataic hydrocarbons and other carcinogens. Reviews in Biochemical Toxicology 1983; 5: 239–265
   Google Scholar
• Morton D. M. The toxicologic evaluation of drug residues. Journal of Environmental Pathology and Toxicology 1980; 3: 65–72
   PubMedGoogle Scholar
• Murphy S. D. Pesticides. Toxicology: The Basic Science of Poisons, 2nd edition, J. Doull, C. D. Klassen, M. O. Amdur. Macmillan Pub. Co, , NY 1980; 357–408
   Google Scholar
• OTA Report. Environmental Contaminants in Food. U.S. Government Printing Office, Washington, DC 1979
   Google Scholar
• Paine A. J., Hockin L. J., Legg R. F. Relationship between the ability of nicotinamide to maintain nicotinamide-adenine dinucleotide in rat liver cell culture and its effect on cytochrome P-450. Biochemistry Journal 1979a; 184: 461–463
   PubMed Web of Science ®Google Scholar
• Paine A. J., Williams L. J., Legg R. F. Apparent maintenance of cytochrome P-450 by nicotinamide in primary cultures of rat hepatocytes. Life Sciences 1979b; 24: 2185–2192
   PubMed Web of Science ®Google Scholar
• Paine A. J., Hockin L. J. Nutrient imbalance causes the loss of cytochrome P-450 in liver cell culture: formulation of culture media which maintain cytochrome P-450 at in vivo concentrations. Biochemical Pharmacology 1980; 29: 3215–3218
   PubMed Web of Science ®Google Scholar
• Paine A. J., Villa P. Ligands maintain cytochrome P-450 in liver cell culture by affecting its synthesis and degradation. Biochemistry and Biophysics Research Communications 1980; 97: 744–750
   PubMed Web of Science ®Google Scholar
• Paulson G. D. Techniques and procedures used to study the metabolism of pesticides in large animals. Fate of Pesticides in Large Animals, G. W. Ivie, H. W. Dorough. Academic Press, Inc., , NY 1977; 17–45
   Google Scholar
• Reese J. A., Byard J. L. Isolation and culture of adult hepatocytes from liver biopsies 1981; 17: 935–940, In Vitro
   PubMedGoogle Scholar
• Rojiking M., Gatmaitan Z., Mackensen S., Giambrone M. -A., Ponce P., Reid L. M. Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal hepatocytes. Journal of Cell Biology 1980; 87: 255–263
   PubMedGoogle Scholar
• St John L. E., Lisk D. J. Fate of the herbicides bromoxynil and casoron in cows. Journal Dairy Science 1967; 50: 582–584
   PubMed Web of Science ®Google Scholar
• St John L. E., Lisk D. J. Metabolic studies with zytron herbicide in a lactating cow. Journal of Agricultural and Food Chemistry 1970; 18: 125–127
   PubMedGoogle Scholar
• St John L. E., Lisk D. J. Feed studies with supracide in the dairy cow. Bulletin of Environmental Contamination and Toxicology 1974; 12: 594–598
   PubMedGoogle Scholar
• Seawright A. A., Steele Filippich L. J. The effect of carbon disulfide used in combination with carbon tetrachloride on the toxicity of the latter drug for sheep. Research in Veterinary Science 1973; 15: 158–166
   PubMedGoogle Scholar
• Seawright A. A., Steele D. P., Mudie A. W., Bishop R. The effect of diet and drugs on hepatic microsomal aminopyrine N-demethylase activity in vitro and susceptibility to carbon tetrachloride in sheep. Research in Veterinary Science 1972; 13: 245–256
   PubMedGoogle Scholar
• Shirkey R. J., Kao J., Fry J. R., Bridges J. W. A comparison of xenobiotic metabolism in cells from rat liver and small intestinal mucosa. Biochemical Pharmacology 1979; 28: 1461–1466
   PubMed Web of Science ®Google Scholar
• Shull L. R., Buckmaster G. W., Cheeke P. R. Factors influencing pyrrolizidine (senecio) alkaloid metabolism: Species, liver sulfhydryls and rumen fermentation. Journal of Animal Science 1976; 43: 1247–1253
   PubMedGoogle Scholar
• Shull L. R., Cheeke P. R. Effects of synthetic and natural toxicants on livestock. Journal of Animal Science 1983; 57(Suppl. 2)330–354
   PubMedGoogle Scholar
• Shull L. R., Kirsch D. G., Lohse C. K., Carlson G. P., Doody L. K., Wisniewski J. A. Xenobiotic metabolism in suspensions and primary cultures of isolated hepatocytes prepared from the caudate process of bovine liver. American Journal of Veterinary Research 1986a; 47: 2043–2052
   PubMedGoogle Scholar
• Shull L. R., Olsen B. A., Hughes B. J., McKenzie R. M., Kinzell J. H. Effect of pentachlorophenol on microsomal mixed-function oxidases in cattle. Pesticide Biochemistry and Physiology 1986b; 25: 31–39
   Google Scholar
• Sirica A. E., Pitot H. C. Drug metabolism and effects of carcinogens in cultured hepatic cells. Pharmacology Reviews 1980; 31: 205–228
   Web of Science ®Google Scholar
• Smith G. S., Watkins J. B., Thompson T. N., Rozman K., Klaassen C. D. Oxidative and conjugative metabolism of xenobiotics by livers of cattle, sheep, swine and rats. Journal of Animal Science 1984; 58: 386–395
   PubMed Web of Science ®Google Scholar
• Smith M. T., Orrenius S. Studies on drug metabolism and drug toxicity in isolated mammalian cells. Drug Metabolism and Drug Toxicity, J. R. Mitchell, M. G. Horning. Raven Press, , NY 1984; 71–98
   Google Scholar
• Steward A. R., Dannan G. A., Guzelian P. S., Guengerich F. P. Changes in the concentration of seven forms of cytochrome P-450 in primary cultures of adult rat hepatocytes. Molecular Pharmacology 1985; 27: 125–132
   PubMed Web of Science ®Google Scholar
• Sullivan L. J., Chin B. H., Carpentar C. P. In vitro vs in vivo chromatographic profiles of carbaryl anionic metabolites in man and lower animals. Toxicology and Applied Pharmacology 1972; 22: 161–174
   PubMed Web of Science ®Google Scholar
• Suolinna E. M. Isolation and culture of liver cells and their use in the biochemical research of xenobiotics. Medical Biology 1982; 60: 237–254
   PubMedGoogle Scholar
• Tanaka K., Sato M., Tomita Y., Ichihava A. Biochemical studies on liver functions in primary cultured hepatocytes of adult rats. I. Hormonal affects on cell viability and protein synthesis. Journal of Biochemistry 1978; 84: 937–946
   PubMed Web of Science ®Google Scholar
• Thurman R. G., Kauffman F. C. Factors regulating drug metabolism in intact hepatocytes. Pharmacology Reviews 1980; 31: 229–251
   Web of Science ®Google Scholar
• Trificante L. J., Siekierski J., Sakalis G., Gershon S. Sulfoxidation of chlorpromazine and thiorazine by bovine liver-preferential metabolic pathways. Biochemical Pharmacology 1979; 28: 621–626
   PubMedGoogle Scholar
• Watkins J. B., Klaassen C. D. Xenobiotic biotransformation in livestock: Comparison to other species commonly used in toxicity testing. Journal of Animal Science 1986; 63: 933–942
   PubMed Web of Science ®Google Scholar
• Weber N. E. Persistent residues: Interface with regulatory decisions. Journal of Environmental Pathology and Toxicology 1980; 3: 35–44
   PubMedGoogle Scholar
• Weber N. E. Metabolism and kinetics in the regulation of animal drugs. Journal of Animal Science 1983; 56: 244–251
   PubMed Web of Science ®Google Scholar
• Whiting F. M., Hagyard S. B., Brown W. H., Stull J. W. Detoxification of DDT by the perfused bovine liver. Journal of Dairy Science 1968; 51: 1612–1615
   PubMedGoogle Scholar
• Williams R. T. Comparative patterns of drug metabolism. Federation Proceedings 1967; 26: 1029–1039
   PubMedGoogle Scholar
• Wisniewski J. A., Moody D. E., Hammock B. D., Shuli L. R. Interlobular distribution of hepatic xenobiotic-metabolizing enzyme activities in cattle, sheep, and goat. Journal of Animal Science 1987; 64, in press
   PubMedGoogle Scholar
• Wright F. C., Riner J. C., Palmer J. S., Schlinke J. C. Metabolic and residue studies with 2-(2,4,5-trichlorophenoxy)-ethyl 2,2-dichloropropionate (erbon) herbicide in sheep. Journal of Agricultural and Food Chemistry 1970; 18: 845–847
   PubMedGoogle Scholar