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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 6
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Original Article

Disposition of α-[(dimethylamino)methyl]-2-(3-ethyl-5-methyl-4-isoxazolyl)-1H-indole-3- methanol (59–801), a hypoglycaemic agent, in rats, dogs and monkeys

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Pages 741-749 | Received 30 May 1986, Published online: 30 Sep 2009

References

  • Hanson R. L., Isaacson C. M. Stimulation of insulin secretion from isolated rat islets by SaRI 59–801. Relation to cAMP concentration and Ca2+ uptake. Diabetes 1985; 34: 691–695
  • Hanson R. L., Isaacson C. M., Boyajy L. D. Stimulation of insulin secretion from isolated rat islets by SaRI 59–801. Diabetes 1985; 34: 548–552
  • Ho R. S., Wiseberg J. J., Brand L. J., Nadelson J., Boyajy L. D. A novel, orally effective hypoglycemic agent, SaRI 59–801, in laboratory animals. Drug Development Research 1985; 6: 67–77
  • Toothaker R. D., Welling P. G. Effect of dose size on the pharmacokinetics of intravenous hydrocortisone during endogenous hydrocortisone suppression. Journal of Pharmacokinetics and Biopharmaceutics 1982; 10: 147–156
  • Tse F. L. S., Orwig B. A., Chang T., Guarducci L., Jaffe J. M. Effect of age on the disposition of α-[(dimethylamino)methyl]-2-(3-ethyl-5-methyl-4-isoxazolyl)-1H-3- indolemethanol in the rat. Drugs under Experimental and Clinical Research 1984; 10: 225–234

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