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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 7
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Original Article

Studies on the metabolism of arylacetic acids. 7. The influence of varying dose size upon the conjugation pattern of 2-naphthylacetic acid in the guinea pig, mouse and hamster

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Pages 823-828 | Received 22 May 1986, Published online: 30 Sep 2009

References

  • Caldwell J. The conjugation reactions. Concepts in Drug Metabolism, Part A, P. Jenner, B. Testa. Marcel Dekker, New York 1980; 211–250
  • Caldwell J., Idle J. R., Smith R. L. The amino acid conjugations. Extrahepatic Metabolism of Drugs and Other Foreign Compounds, T. E. Gram. SP Medical Books, New York 1980; 453–492
  • Dixon P. A. F., Caldwell J., Smith R. L. Studies on the metabolism of arylacetic acids. 1. The metabolic fate of 1-naphthylacetic acid and its variation with species and dose. Xenobiotica 1977; 7: 695–706
  • Emudianughe T. S., Caldwell J., Smith R. L. Studies on the metabolism of arylacetic acids. 5. The metabolic fate of 2-naphthylacetic acid in the rat, rabbit and ferret. Xenobiotica 1978; 8: 525–534
  • Emudianughe T. S., Caldwell J., Smith R. L. Studies on the metabolism of arylacetic acids. 6. Comparative metabolism of 1- and 2-naphthylacetic acids in the guinea pig, mouse, hamster and gerbil. Xenobiotica 1987; 17: 815–821
  • Killenberg P. G., Webster L. T. Conjugation of peptide bond formation. Enzymatic Basis of Detoxication, W. B. Jakoby. Academic Press, New York 1980; Vol. II: 141–167
  • Marsh M., Varwell V., Caldwell J., Smith R. L., Horner M. W., Houghton E., Moss M. S. The metabolic conjugation of some carboxylic acids in the horse. Xenobiotica 1981; 11: 655–663
  • Mulder G. J. Conjugation of phenols. Metabolic Basis of Detoxication, W. B. Jakoby, J. R. Bende, J. Caldwell. Academic Press, New York 1982; 247–269
  • Zangouras A., Caldwell J., Hutt A. J., Smith R. L. Dose-dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite, 1′-hydroxyestragole. Biochemical Pharmacology 1981; 30: 1383–1386

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