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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 1
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Original Article

Sex differences in the production of methaemoglobinaemia by 4-aminopropiophenone

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Pages 79-83 | Received 15 Dec 1985, Published online: 30 Sep 2009

References

  • BRIGHT, J. E., and MARRS, T. C., 1982, A model for the induction of moderate levels of met-haemoglobinaemia in man using 4-dimethylaminophenol, Archives of Toxicology, SO, 57–64.
  • BRIGHT, J. E., and MARRS, T. C., 1986, Kinetics of methaemoglobin production by PAPP or DMAP, British Journal of Pharmacology, 87, 119 p.
  • CALABRESE, E. J., 1983, Principles of Animal Extrapolation. New York, John Wiley Inc.
  • GRAFFE, W., KIESE, M., and RAUSCHER, E., 1964, The formation in vivo of p-hydroxyl-aminopropiophenone from p-aminopropiophenone and its action in vivo and in vitro, Naunyn-Schmiedebergs Archives of Experimental Pathology and Pharmacology, 249, 168–175.
  • HURST, E. W., 1957, Sexual differences in the toxicity and therapeutic action of chemical substances. In Drug Toxicity ed A. L. Walpole. Boston, Little Brown.
  • VON AGOW, R., KIESE, M., and RENNER, G., 1966, Urinary excretion of N-hydroxy derivatives of some aromatic amines by rabbits, guinea pigs and dogs, Biochemical Pharmacology, 15, 1899–1910.
  • JANDORF, B. J., and BODANSICY, O., 1946, Therapeutic and prophylactic effect of methemoglobinemia in inhalation poisoning by hydrogen cyanide and cyanogen chloride, Journal of Industrial Hygiene and Toxicology, 28, 125–132.
  • KIESE, M., 1974, Methernoglobinemia, A Comprehensive Treatise, Cleveland Ohio, CRC Press.
  • KLIMMEK, R., RODDEWIG, C., FLADE.RER, H., KRETTEK, C., and WEGER, N., 1983, Effects of 4-dimethylaminophenol, Co2EDTA, or NaNO2 on cerebral blood flow and sinus blood homeostasis of dogs in connection with acute cyanide poisoning, Toxicology, 26,143–154.
  • ROSE, C. L., WELLES, J. S., FINC, J. D., and CHEN, K. K., 1947, The antidotal action of p-aminipropiophenone with or without sodium thiosulfate in cyanide poisoning. Journal of Pharmacology, 80, 31–38.
  • SCAWIN, J. W., SWANSTON, D. W., and MARRS, T. C., 1984, The acute oral and intravenous toxicity of p-aminopropiophenone (PAPP) to laboratory rodents. Toxicology Letters, 23, 359–365.
  • TEPPERMAN, J., and BODANSKY, O., 1946, The role of hepatic detoxification in p-aminopropiophenone induced methaemoglobinemia. Journal of Pharmacology and Experimental Therapy, 88, 287–299.

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