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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 10
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Original Article

Sulphoxidation of albendazole by the FAD-containing and cytochrome P-450 dependent mono-oxygenases from pig liver microsomes

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Pages 1159-1168 | Received 30 Jul 1986, Published online: 30 Sep 2009

References

  • Barrowman M. M., Marriner S. E., Bogan J. A. The binding and subsequent inhibition of tubulin polymerisation in ascaris suum (in vitro) by benzimidazole anthelmintics. Biochemical Pharmacology 1984; 33: 3037–3040
  • Damani L. A. Metabolism of sulfur containing drugs. 10th European Drug Metabolism Workshop. 1986; 9, Guildford (GB), Abstract L18, p.
  • Delatour P., Parish R. C., Gyurik R. J. Albendazole: a comparison of relay embryotoxicity with embryotoxicity of individual metabolites. Annales de Recherche Vétérinaire 1981; 12: 159–167
  • Delatour P., Garnier F., Benoit E., Longin C. A correlation of toxicity of albendazole and oxfendazole with their free metabolites and bound residues. Journal of Veterinary Pharmacology and Therapeutics 1984; 7: 139–145
  • Douch P. G. L., Buchanan L. L. Some properties of sulfoxidases and sulfoxide reductases of the cestode Monieza expansa, the nematode Ascaris suum and mouses liver. Xenobiotica 1979; 9: 675–679
  • Fargetton X., Galtier P., Delatour P. Sulfoxidation of albendazole by a cytochrome P-450-independent monooxygenase from rat liver microsomes. Veterinary Research Communications 1986; 10: 317–324
  • Faure A., Nemoz C., Fargetton X. Computerized method for determination of Km and Vmax values from measures of enzymatic activities with end point method. Computer Programs in Biomedicine 1986; 22: 163
  • Galtier P., Alvinerje M., Delatour P. In vitro sulfoxidation of albendazole by bovine liver microsomes. American Journal of Veterinary Research 1986; 47: 447–450
  • Gyurik R. J., Chow A. W., Zaber B., Bruner E. L., Miller J. A., Villani A. J., Petka L. A., Parish R. C. Metabolism of albendazole in cattle, sheep, rats and mice. Drug Metabolism and Disposition 1981; 19: 503–508
  • Hajjar N. P., Hodgson E. Flavine adenine dinucleotide, dependent monooxygenase: its role in the sulfoxidation of pesticides in mammals. Science 1980; 209: 1134–1136
  • Ivanetich K. H., Costa A. K., Brittain T. Limitations on the metyrapone assay for the major phenobarbital inducible form of cytochrome P-450. Biochemical and Biophysical Communications 1982; 105: 1322–1326
  • Jefcoate C. R. E., Gaylor G. L., Calabrese R. L. Ligand interaction with cytochrome P-450. I. binding of primary amine. Biochemistry 1980; 8: 3455–3463
  • Kamataki T., Sugiuna M., Yamazoe Y., Kato R. Purification and properties of cytochrome P-450 and NADPH-cytochrome C (P-450) reductase from human liver microsomes. Biochemical Pharmacology 1993; 28, 2000
  • Kedderis G. L., Rickert D. E. Loss of rat microsomal cytochrome P-450 during methimazole metabolism: Role of flavin containing monooxygenase. Drug Metabolism and Disposition 1985; 13: 58–61
  • Kitchell B. B., Rauckman E. S., Rosen G. M. The effect of temperature on mixed function amine oxidase intrinsic fluorescence and oxidative activity. Molecular Pharmacology 1978; 14: 1092–1098
  • Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 272: 680–685
  • Le Provost E., Flinois J. P., Beaune Ph., Leroux J. P. Immunochemical characterization of some monooxyenase activities in liver microsomes from untreated and phenobarbital-treated rats. Biochemical and Biophysical Research Communications 1981; 101: 547–554
  • Lesca P., Lecointe P., Paoletti C., Mansuy D. Ellipticines as potent inhibitors of arylhydrocarbon hydroxylase: Their binding to microsomal cytochromes P-450 and protective effect against benzo[a]pyrene mutagenicity. Biochemical Pharmacology 1978; 27: 1203–1209
  • Mazel P. Experiments illustrating drug metabolism in vitro. Fundamentals of drug metabolism and drug disposition, B. N. La Du, H. G. Mandel, E. L. Way. Waverley Press Inc., Baltimore, USA 1971; 546–582
  • Marriner S. E., Bogan J. A. Pharmacokinetics of albendazole in sheep. American Journal of Veterinary Research 1980; 41: 1126–1129
  • Mitchell S. C., Waring R. H. The early history of xenobiotic sulfoxidation. Drug Metabolism Reviews 1986; 16: 255–284
  • Netter K. J., Seidel B. L. An adaptively stimulated O-demethylating system in rat liver microsomes and its kinetic properties. Journal of Pharmacology and Experimental Therapeutics 1964; 146: 61–65
  • Oae S., Mikami A., Matsuura T., Ogawa-Asada K., Watanabe Y., Fujimori K., Iyanagi T. Comparison of sulfide oxygenation mechanism for liver microsomal FAD-containing monooxygenase with that for cytochrome P-450. Biochemical and Biophysical Research Communications 1985; 131: 567–573
  • Penicaut B., Maugein P. H., Maisonneuve H., Rossignol J. F. Pharmacocinétique et metabolisme urinaire de l'albendazole chez l'homme. Bulletin de le Société Pathologie Expérimentale 1983; 76: 698–708
  • Poulsen L. L., Hyslop R. M., Ziegler D. M. S.oxygenation of N. substituted thioureas catalysed by the pig liver microsomal FAD-containing monooxygenase. Archives of Biochemistry and Biophysics 1979; 198: 78–88
  • Prichard R. K., Henessy D. R., Steel J. N., Lacey E. Metabolite concentrations in plasma following treatment of cattle with five anthelmintics. Research Veterinary Science 1985; 39: 173–178
  • Prough A. R., Ziegler D. M. The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions. Archives of Biochemistry and Biophysics 1977; 180: 363–373
  • Saimot A. G., Crémieux A. C., Hay J. M., Meulemans A., Giovanangeli M. D., Delaitre B., Coulaud J. P. Albendazole as a potential treatment for human hydatidosis. The Lancet 1983; 17: 652–656
  • Schenkman J. B. S. Studies on the nature of Type I and Type II spectral changes in liver microsomes. Biochemistry 1970; 9: 2081–3011
  • Theodorides V. J., Gyurik R. J., Kingsbury W. D., Parish R. C. Anthelmintic activity of albendazole against liver flukes, tapeworms lung and gastrointestinal roundworms. Experimentia 1976; 32: 702–703
  • Tynes R. E., Hodgson E. Oxidation of thiobenzamide by the FAD containing and cytochrome P-450 dependent monooxygenase of liver and lung microsomes. Biochemical Pharmacology 1983; 32: 3419–3428
  • Ullrich V., Weber P. The O-dealkylation of 7-ethoxycoumarin by liver microsomes: a direct fluorimetric assay. Hoppe Seyler's Zeitschrift für Physiologie und Chemie 1972; 353: 1171–1177
  • Yang C. S., Strickhart F. S. Inhibition of hepatic mixed function oxidase activity by propylgallate. Biomedical Pharmacology 1974; 23: 3129–3138
  • Yasukochi Y., Masters B. S. S. Some properties of a detergent-solubilized NADPH-cytochrome c (cytochrome P-450) reductase purified by biospecific affinity chromatography. Journal of Biological Chemistry 1976; 251: 5337–5344
  • Ziegler D. M. Microsomal flavin containing monooxygenase, oxygenation of nucleophilic nitrogen and sulfur containing compounds. Enzymatic Basis of Detoxification, W. B. Jakoby. Academic Press, New York 1980; 201–227

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