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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 4
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Original Article

Ethosuximide disposition kinetics in rats

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Pages 373-380 | Received 15 Apr 1987, Accepted 27 Nov 1987, Published online: 30 Sep 2009

References

  • Bachmann K., Yang C., Jahn D., Schwartz J. Using single sample clearance estimates to probe hepatic drug metabolism in rats I. Xenobiotica 1988a; 18: 149–157
  • Bachmann K., Jahn D., Yang C., Schwartz J. Using single sample clearance estimates to probe hepatic drug metabolism in rats II. Xenobiotica 1988b; 18: 159–164
  • Glazer R., Cinti D., Murahata R., Schenkman J., Sartorelli A. Metabolic action of urethane on protein synthesis and drug oxidation in normal and regenerating liver. Biochemical Pharmacology 1972; 21: 2867–2875
  • Glazko A. Antiepileptic drugs: biotransformation, metabolism, and serum half-life. Epilepsia 1975; 16: 376–391
  • Horning M. G., Stratton C., Nowlin J., Harvey D. J., Hill R. M. Metabolism of 2-ethyl-2-methylsuccinimide (ethosuximide) in the rat and human. Drug Metabolism and Disposition 1973; 1: 569–576
  • Orton T. C., Nicholls P. J. Effect in rats of subacute administration of ethosuximide, methsuximide and phensuximide on hepatic microsomal enzymes and porphyrin turnover. Biochemical Pharmacology 1972; 21: 2253–2261
  • Reitberg D., Smith I., Love S., Lewing H., Schentag J. A rapid, universal TI-59 model-independent pharmacokinetic analysis program based on statistical moment theory. Drug Intelligence and Clinical Pharmacy 1985; 19: 124–135
  • Stevenson I. H., O'Malley K., Shepherd A. M. M. Relative induction potency of anticonvulsant drugs. Anticonvulsant Drugs and Enzyme Induction, A. Richens, F. P. Woodford. Elseview, Oxford 1976; 37–46
  • Wagner J. Fundamentals of Clinical Pharmacokinetics. Drug Intelligence Publications, Hamilton, Illinois 1975; 247–284

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