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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 5
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Original Article

Enhanced faecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats by a long-term treatment with activated charcoal beads

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Pages 585-592 | Received 20 Jul 1987, Accepted 08 Jan 1988, Published online: 30 Sep 2009

References

  • Ernster L., Danielson L., Ljunggren M. DT-diaphorase. I. Purification from the soluble fraction of rat liver cytoplasm and properties. Biochimica et Biophysica Acta 1962; 58: 171–188
  • Folch J., Lees M., Stanley G. H. S. A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 1957; 226: 497–509
  • Fukasaku N., Hasegawa M., Kuroki H., Masuda Y., Koga N., Yoshimura H. Synthesis of 14C-2,3,4,7,8-pentachlorodibenzofuran. Fukuoka Acta Medica 1983; 74: 202–205
  • Kuroki H., Masuda Y. Determination of polychlorinated dibenzofuran isomers retained in patients with Yusho. Chemosphere 1978; 7: 771–777
  • Kuroki H., Masuda Y., Yoshihara S., Yoshimura H. Accumulation of polychlorinated dibenzofurans in the livers of monkeys and rats. Food and Cosmetics Toxicology 1980; 18: 387–392
  • Kiroki J., Koga N., Yoshimura H. High Affinity of 2,3,4,7,8-pentachlorodibenzofuran to cytochrome P-450 in the hepatic microsomes of rats. Chemosphere 1986; 15: 731–738
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurements with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Masuda Y., Yoshimura H. Polychlorinated biphenyls and dibenzofurans in patients with Yusho and toxicological significance: A Review. American Journal of Industrial Medicine 1984; 5: 31–44
  • Matsubara T., Koike M., Touchi A., Tochino Y., Sugeno K. Quantitative determination of cytochrome P-450 in rat liver homogenate. Analytical Biochemistry 1976; 75: 596–603
  • Nakano N. I., Funada S., Honda Y., Nakano M. In vitro adsorption characteristics of bile salt anions by activated carbon beads for oral administration. Chemical and Pharmaceutical Bulletin 1984a; 32: 4096–4102
  • Nakano N. I., Shimamori Y., Umehashi M., Nakano M. Preparation and drug adsorption characteristics of activated carbon beads suitable for oral administration. Chemical and Pharmaceutical Bulletin 1984b; 32: 699–707
  • Nebert D. W., Gelboin H. V. Substrate inducible microsomal aryl hydroxylase in mammalian cell culture. Journal of Biological Chemistry 1968; 243: 6242–6249
  • Oguri K., Kamimura H., Koga N., Yoshimura H. Mechanisms for stimulated fecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats by treatment with squalane and liquid paraffin. Chemosphere 1987; 16: 1707–1712
  • Pluss N., Poiger H., Schlatter C., Buser H. R. The metabolism of some pentachloro-dibenzofurans in the rat. Xenobiotica 1987; 17: 209–216
  • Rappe C., Buser H. R., Kuroki H., Masuda Y. Identification of polychlorinated dibenzofurans (PCDFs) retained in patients with Yusho. Chemicals 1979; 8: 259–266
  • Richter E., Fichtl B., Schäfer S. G. Effects of dietary paraffin, squalane and sucrose polyester on residue disposition and elimination of hexachlorobenzene in rats. Chemico-Biological Interactions 1982; 40: 335–344
  • Richter E., Lay J. P., Klein W., Korte F. Paraffin-stimulated excretion of 2,4,6,2′,4′-pentachlorobi‘14C’phenyl by rats. Toxicology and Applied Pharmacology 1979; 50: 17–23
  • Richter E., Schäfer S. G., Fichtl B. Stimulation of the faecal excretion of 2,4,5,2′,4′,5′-hexachlorobiphenyl in rats by squalane. Xenobiotica 1983; 13: 337–343
  • Wilson K. A., Cook R. M. Use of activated carbon as an antidote for pesticide poisoning in ruminants. Journal of Agricultural and Food Chemistry 1970; 18: 437–440
  • Yoshihara S., Nagata K., Yoshimura H., Kuroki H., Masuda Y. Inductive effect of hepatic enzymes and acute toxicity of individual polychlorinated dibenzofuran congeners in rats. Toxicology and Applied Pharmacology 1981; 59: 580–588
  • Yoshimura H., Kamimura H., Oguri K., Honda Y., Nakano M. Stimulating effect of activated charcoal beads on faecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats. Chemosphere 1986; 15: 219–227
  • Yoshimura H., Kamimura H., Oguri K., Saeki S. Stimulating effect of squalane on faecal excretion of a high toxic 2,3,4,7,8-pentachlorodibenzofuran (PenCDF) in rats. Fukuoka Acta Medica 1985; 76: 184–189
  • Yoshimura H., Kuroki J., Koga N., Kuroki H., Masuda Y., Fukasaku N., Hasegawa M. High accumulation of 2,3,4,7,8-pentachlorodibenzofuran to hepatic microsomes of rats. Journal of Pharmacobio-Dynamics 1984; 7: 414–419

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