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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 1
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Research Article

Metabolism profiles and excretion of 14C-aminoglutethimide in several animal species and man

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Pages 75-81 | Received 23 Jan 1987, Published online: 22 Sep 2008

References

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  • Damanhouri Z., Nicholls P. J. Induction of mixed function oxidase activity of rat and mouse liver by aminoglutethimide. British Journal of Pharmacology 1986; 88: 430P
  • Egger H., Bartlett F., Itterly W., Rodebaugh R., Shimanskas C. Metabolism of aminoglutethimide in the rat. Drug Metabolism and Disposition 1982; 10: 405–412
  • Eweiss N. Synthetic and metabolism studies with aminoglutethimide. PhD Thesis, University of Wales. 1981
  • Foster A. B., Griggs L. J., Howe I., Jarman M., Leung C. -S., Manson D., Rowlands M. G. Metabolism of aminoglutethimide in humans: identification of four new urinary metabolites. Drug Metabolism and Disposition 1984; 12: 511–516
  • Jarman M., Foster A. B., Goss P. E., Griggs L. J., Howe I., Coombes R. C. Metabolism of aminoglutethimide in humans: identification of hydroxylaminoglutethimide as an induced metabolite. Biomedical Mass Spectrometry 1983; 10: 620–625
  • Nicholls P. J., Daly M. J., Smith H. J. Pharmacology of aminoglutethimide: structure/activity relationships and receptor interactions. Breast Cancer Research and Treatment 1986; 7: 55–68
  • Santen R. J., Worgul T. J., Lipton A., Harvey H., Boucher A., Samojlik E., Wells S. A. Aminoglutethimide as treatment of postmenopausal women with advanced breast carcinoma. Annals of Internal Medicine 1982; 96: 94–101

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