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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 1
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Original Article

Comparative microsomal oxidation of febantel and its metabolite fenbendazole in various animal species

Clara Montesissa Institute of Veterinary Phamacology and Toxicology University of Milan, Via Celoria 10, 20133, Milan, Italy
,
Jose Malvisi Stracciari Institute of Pharmacology, Pharmacokinetics and Toxicology, Fac. of Vet. Medicine, Strada Maggiore 45, 40125, Bologna, Italy
,
Luigi Fadini Institute of Veterinary Phamacology and Toxicology University of Milan, Via Celoria 10, 20133, Milan, Italy
&
Carlo Beretta Institute of Veterinary Phamacology and Toxicology University of Milan, Via Celoria 10, 20133, Milan, Italy
Pages 97-100 | Received 24 Apr 1988, Accepted 18 Aug 1988, Published online: 30 Sep 2009

References

  • Beretta C., Fadini L., Malvisi Stracciari J., Montesissa C. In vitro febantel transformation by sheep and cattle ruminal fluids and metabolism by hepatic subcellular fractions from different animal species. Biochemical Pharmacology 1987; 19: 3107–3114
  • Delatour P., Daudon M., Garnier F., Benoit E. Relation metabolisme-embryotoxicite du febantel chez le rat et le mouton. Annales de recherches veterinaire 1982; 13: 163–170
  • Souhaili El-Amri H., Fargetton X., Benoit E., Totis M., Batt A. M. Inducing effects of Albendazole on rat liver drug-metabolizing enzymes and metabolite pharmacokinetics. Toxicology and Applied Pharmacology 1987; 92: 141–149

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