Cytochrome P-450 and oxidative metabolism in molluscs

References

• Ade P., Banchelli Soldani M. G., Castelli M. G., Cheisara E., Clementi F., Fanelli R., Funari E., Ingnesti G., Marabini A., Oronesu M., Palmero S., Pirisino R., Orlando Ramundo A., Silano V., Viarengo A., Vitozzi L. Comparative biochemical and morphological characterizations of microsomal preparations from rat, quail, trout, mussel and Daphnia magna. Cytochrome P-450 Biochemistry, Biophysics and Environmental Implications, E. Hieanen, M. Laitinen, O. Hanninen. Elsevier, Amsterdam 1982; 387–390
   Google Scholar
• Aikawa T., Aikawa Y., Horiuchi S. Distribution of acid proteinase activity in molluscs. Biochemical Systematics and Ecology 1982; 10: 175–179
   Google Scholar
• Anderson R. S. Benzo‘a’pyrene metabolism in the American oyster Crassostrea virginica. EPA Ecology Research Series Monograph, 1978a, (EPA-600/3-78-009)
   Google Scholar
• Anderson R. S. Developing an invertebrate model for chemical carcinogenesis: metabolic activation of carcinogens. Comparative Pathobiology 1978b; 4: 11–24
   Google Scholar
• Anderson R. S. Metabolism of a model environmental carcinogen by bivalve molluscs. Marine Environmental Research 1985; 17: 137–140
   Google Scholar
• Anderson R. S., Döös J. E. Activation of mammalian carcinogens to bacterial mutagens by microsomal enzymes from a pelecypod mollusc. Mercenaria mercenaria. Mutation Research 1983; 116: 247–256
   PubMedGoogle Scholar
• Åstrom A., DePierre J. W. Rat-liver microsomal cytochrome P-450: purification, characterisation, multiplicity and induction. Biochimica et Biophysica Acta 1986; 853: 1–27
   PubMedGoogle Scholar
• Britvic S., Kurelec B. Selective activation of carcinogenic aromatic amines to bacterial mutagens in the marine mussel Mytilus galloprovincialis. Comparative Biochemistry and Physiology 1986; 85C: 111–114
   Google Scholar
• Cavalieri E. L., Rogan E. G. One-electron and two-electron oxidation in aromatic hydrocarbon garcinogenesis. Free Radicals in Biology, W. A. Pryor. Academic Press, New York 1984; vol. VI: 323–369
   Google Scholar
• Cavalieri E. L., Rogan E. G. one-electron oxidation in aromatic hydrocarbon carcinogenesis. Polycyclic Hydrocarbons and Carcinogenesis, R. G. Harvey. American Chemical Society, Washington, DC 1985; 289–305
   Google Scholar
• Dawson J. H. Probing structure-function relations in haem-containing oxygenases and peroxidases. Science 1988; 240: 433–439
   PubMed Web of Science ®Google Scholar
• Galli A., Del Chiero D., Nieri R., Bronzetti G. Studies on cytochrome P-450 in Mytilus galloprovincialis: induction by Na-phenobarbital and ability to biotransform xenobiotics. Marine Biology 1988; 100: 69–73
   Google Scholar
• Geyer H., Sheenan P., Kotzias D., Freitag D., Korte F. Prediction of ecotoxicological behaviour of chemicals: relationship between physicochemical properties and bioaccumulation of organic chemicals in the mussel Mytilus edulis. Chemosphere 1982; 11: 1121–1134
   Web of Science ®Google Scholar
• Gilewicz M., Guillaume J. R., Carles D., Leveau M., Bertrand J. C. Effects of petroleum hydrocarbons on the cytochrome P-450 content of the mollusc bivalve Mytilus galloprovincialis. Marine Biology 1984; 80: 155–159
   Web of Science ®Google Scholar
• Goldberg E. D., Bowen V. T., Farrington J. W., Harvey G., Martin J. H., Parker P. L., Risebrough R. W., Robertson W., Schneider E., Gamble E. The mussel watch. Environmental Conservation 1978; 5: 101–125
   Web of Science ®Google Scholar
• Gower J. D., Wills E. D. The generation of oxidation products of benzo‘a’pyrene by lipid peroxidation: a study using γ-irradiation. Carcinogenesis 1984; 5: 1183–1189
   PubMed Web of Science ®Google Scholar
• Gschwend P. M., MacFarlane J. K., Newman K. A. Volatile halogenated organic compounds released to seawater from temperate marine macrolagae. Science 1985; 227: 1033–1035
   PubMed Web of Science ®Google Scholar
• Hansen L. G., Kapoor I. P., Metcalf. Biochemistry of selective toxicity and biodegradability: comparative O-dealkylation by aquatic organisms. Comparative and General Pharmacology 1972; 3: 339–344
   PubMedGoogle Scholar
• Hawkins J. M., Jones W. E., Bonner F. W., Gibson G. G. The effect of peroxisome proliferators on microsomal, peroxisomal, and mitochrondrial enzyme activities in the liver and kidney. Drug Metabolism Reviews 1987; 18: 441–515
   PubMed Web of Science ®Google Scholar
• The Mollusca, Vol. I: Metabolic Biochemistry and Molecular Biomechanics, P. W. Hochachka. Academic Press, New York 1983a
   Google Scholar
• The Mollusca, Vol. II: Environmental Biochemistry and Physiology, P. W. Hochachka. Academic Press, New York 1983b
   Google Scholar
• Houdi A. A., Damani L. A. N-demethylation and N-oxidation of N,N-dimethylaniline by rat liver microsomes. Biological Oxidation of Nitrogen in Organic Molecules, J. W. Gorrod, L. A. Damani. Ellis Horwood, Chichester 1985; 96–100
   Google Scholar
• Khan M. A. Q., Kamal A., Wolin R. J., Runnels J. In vivo and in vitro epoxidation of aldrin by aquatic food chain organisms. Bulletin of Environmental Contamination and Toxicology 1972; 8: 219–228
   PubMedGoogle Scholar
• Kirchin M. A. Cytochrome P-450 of the common mussel. Mytilus edulis L: partial purification and characterization. Ph.D. dissertation, University of Surrey, England 1988
   Google Scholar
• Kirchin M. A., Wiseman A., Livingstone D. R. The partial purification of cytochrome P-450 from the digestive gland of the common mussel. Mytilus edulis. Biochemical Society Transactions 1987; 15: 1100–1101
   Web of Science ®Google Scholar
• Kirchin M. A., Wiseman A., Livingstone D. R. Studies on the mixed-function oxygenase system of the marine bivalve. Mytilus edulis. Marine Environmental Research 1988; 24: 117–118
   Web of Science ®Google Scholar
• Knezovich J. P., Crosby D. G. Fate and metabolism of o-toluidine in the marine bivalve molluscs, Mytilus edulis and Crassostreagigas. Environmental Toxicology and Chemistry 1985; 4: 435–446
   Web of Science ®Google Scholar
• Knezovich J. P., Lawton M. P., Harrison F. L. In vivo metabolism of aromatic amines by the bay mussel Mytilus edulis. Marine Environmental Research 1988; 24: 89–91
   Google Scholar
• Koivusaari U., Lindstrom-Seppa P., Lang M., Harri M., Hanninen O. Occurrence of cytochrome P-450 in certain fresh water species in northern Europe. Biochemistry, Biophysics and Regulation of Cytochrome P-450, J. A. Gustafsson, J. Carlstedt-Duke, A. Mode, J. Rafter. Elsevier, North-Holland, Amsterdam 1980; 455–458
   Google Scholar
• Krieger R. I., Gee S. J., Lim L. O. Marine bivalves, particularly mussels, Mytilus sp., for assessment of environmental quality. Ecotoxicology and Environmental Safety 1981; 5: 72–86
   PubMedGoogle Scholar
• Krieger R. I., Gee S. J., Lim L. O., Ross J. H., Wilson A. Disposition of toxic substances in mussels (Mytilus californianus): preliminary metabolic and histologic studies. Pesticide and Xenobiotic Metabolism in Aquatic Organisms, M. A. Q. Khan, J. J. Lech, J. J. Menn. American Chemical Society Symposium Series, 1979; 99: 259–277
   Google Scholar
• Kurelec B. Exclusive activation of aromatic amines in the marine mussel Mytilus edulis by FAD-containing monooxygenase. Biochemical and Biophysical Research Communications 1985; 127: 773–778
   PubMed Web of Science ®Google Scholar
• Kurelec B. Comment on: D. R. Livingstone's critique. (Mar. Biol) 1987; 94: 319–320, 1987, of the paper ‘Metabolic fate of aromatic amines in the mussel Mytilus galloprovincialis’. Marine Biology, 94, 321–322
   Google Scholar
• Kurelec B., Krca S. Metabolic activation of 2-aminofluorene, 2-acetylaminofluorene and N-hydroxy-acetylaminofluorene to bacterial mutagens with mussel (Mytilus galloprovincialis) and carp (Cyprinus carpio) subcellular preparations. Comparative Biochemistry and Physiology 1987; 88C: 171–177
   Google Scholar
• Kurelec B., Britvic S., Zahn R. K. The activation of aromatic amines in some marine invertebrates. Marine Environmental Research 1985; 17: 141–144
   Google Scholar
• Kurelec B., Chacko M., Gupta R. C. Postlabelling analysis of carcinogen-DNA adducts in mussel Mytilus galloprovincialis. Marine Environmental Research 1988; 24: 317–320
   Web of Science ®Google Scholar
• Kurelec B., Britvic S., Krca S., Zahn R. K. Metabolic fate of aromatic amines in the mussel, Mytilus galloprovincialis. Marine Biology 1986; 91: 523–527
   Web of Science ®Google Scholar
• Landrum P. F., Crosby D. G. Comparison of the disposition of several nitrogen-containing compounds in the sea urchin and other marine invertebrates. Xenobiotica 1981; 11: 351–361
   PubMed Web of Science ®Google Scholar
• Lee R. F. Mixed function oxygenase (MFO) in marine invertebrates. Marine Biology Letters 1981; 2: 87–105
   Web of Science ®Google Scholar
• Lee R. F. Metabolism of tributyltin oxide by crabs, oysters and fish. Marine Environmental Research 1985; 17: 145–148
   Google Scholar
• Lee R. F. Metabolism of bis (tributyltin) oxide by estuarine animals. Proceedings of Oceans 86. Marine Technology Society, Washington, DC 1986; Vol. 4: 1182–1188, Organotin Symposium
   Google Scholar
• Lee R. F., Furlong E., Singer S. Metabolism of hydrocarbons in marine invertebrates: aryl hydrocarbon hydroxylase from the tissues of the blue crab, Callinectes sapidus and the polychaete worm, Nereis sp. Pollutant Effects on Marine Organisms, C. S. Giam. Lexington Books, Lexington, MA 1977; 111–124
   Google Scholar
• Lee R. F., Sauerhebel R., Benson A. A. Petroleum hydrocarbons: uptake and discharge by the marine mussel Mytilus edulis. Science 1972; 177: 344–346
   PubMed Web of Science ®Google Scholar
• Lehtovaara I., Koskinen T. Demonstration of vitamin D3 metabolism in, Mytilus edulis. Experientia 1986; 42: 147–148
   Google Scholar
• Livingstone D. R. Invertebrate and vertebrate pathways of anaerobic metabolism: evolutionary considerations. Journal of the Geological Society of London 1983; 140: 27–37
   Web of Science ®Google Scholar
• Livingstone D. R. Biochemical differences in field populations of the common mussel Mytilus edulis L. exposed to hydrocarbons: some considerations of biochemical monitoring. Toxins, Drugs and Pollutants in Marine Animals, L. Bolis, J. Zadunaisky, R. Gilles. Springer-Verlag, Berlin 1984; 161–175
   Google Scholar
• Livingstone D. R. Responses of the detoxication/toxication enzyme systems of molluscs to organic pollutants and xenobiotics. Marine Pollution Bulletin 1985; 16: 158–164
   Web of Science ®Google Scholar
• Livingstone D. R. Seasonal responses to diesel oil and subsequent recovery of the cytochrome P-450 monooxygenase system in the common mussel, Mytilus edulis L., and the periwinkle, Littorina littorea L. Science of the Total Environment 1987a; 65: 3–20
   Web of Science ®Google Scholar
• Livingstone D. R. Comment on 'Metabolic fate of aromatic amines in the mussel Mytilus galloprovincialis, B. Kurelec, et al, 1987b, Mar. Biol, 91, 523–527, 1986, Marine Biology, 94, 319–320
   Google Scholar
• Livingstone D. R. Responses of microsomal NADPH-cytochrome c reductase activity and cytochrome P-450 in digestive glands of Mytilus edulis and Littorina littorea to environmental and experimental exposure to pollutants. Marine Ecology Progress Series 1988; 46: 37–43
   Web of Science ®Google Scholar
• Livingstone D. R., Farrar S. V. Tissue and subcellular distribution of enzyme activities of mixed-function oxygenase and benzo‘a’pyrene metabolism in the common mussel, Mytilus edulis L. Science of the Total Environment 1984; 39: 209–235
   Web of Science ®Google Scholar
• Livingstone D. R., De Zwaan A., Leopold M., Marteijn E. Studies on the phylogenetic distribution of pyruvate oxidoreductases. Biochemical Systematics and Ecology 1983; 11: 415–425
   Web of Science ®Google Scholar
• Livingstone D. R., Farrar S. V., Fossi C., Kirchin M. A., Moore M. N. Responses of the Digestive Gland Cytochrome P-450 Monoxygenase System of the Common Mussel (Mytilus edulis) to 3-Methylcholanthrene and Sodium Phenobarbital. Marine Environmental Research 1988a; 24: 118–119
   Web of Science ®Google Scholar
• Livingstone D. R., Martinez Garcia P., Stegeman J. J., Winston G. W. Benzo‘a’pyrene metabolism and aspects of oxygen radical generation in the common mussel. Mytilus edulis L. Biochemical Society Transactions 1988b; 16: 779
   Web of Science ®Google Scholar
• Livingstone D. R., Moore M. N., Lowe D. M., Nasci C., Farrar S. V. Responses of the cytochrome P-450 monooxygenase system to diesel oil in the common mussel, Mytilus edulis L., and the periwinkle, Littorina littorea L. Aquatic Toxicology 1985; 7: 79–91
   Google Scholar
• Livingstone D. R., Stickle W. B., Kapper M., Wang S. Microsomal detoxication enzyme responses of the marine snail, Thais haemastoma, to laboratory oil exposure. Bulletin of Environmental Contamination and Toxicology 1986; 36: 843–850
   PubMedGoogle Scholar
• Marnett L. J. Hydroperoxide-dependent oxygenation of polycylic aromatic hydrocarbons and their metabolites. Polycyclic Hydrocarbons and Carcinogenesis, R. G. Harvey. American Chemical Society, Washington, DC 1985; 307–326
   Google Scholar
• Marnett L. J., Weller P., Battista J. R. Comparison of the peroxidase activity of hemoproteins and cytochrome P-450. Cytochrome P-450. Structure, Mechanism and Biochemistry, P. R. Ortiz de Montellano. Plenum Press, New York 1986; 29–76
   Google Scholar
• Meyer T., Bakke T. The metabolism of biphenyl. V. Phenolic metabolites in some marine organisms. Acta Pharmacologica et Toxicologica 1977; 40: 201–208
   PubMedGoogle Scholar
• Mix M. C., Schaffer R. L., Hemingway S. J. Polynuclear aromatic hydrocarbons in bay mussels (Mytilus edulis) from Oregon. Phyletic Approaches to Cancer, C. J. Dawe, J. C. Harshbarger, S. Kondo, T. Sugimura, S. Takayama. Japan Scientific Press, Tokyo 1981; 167–177
   Google Scholar
• Moore M. N. Cellular responses of polycyclic aromatic hydrocarbons and phenobarbital in Mytilus edulis. Marine Environmental Research 1979; 2: 255–263
   Google Scholar
• Moore M. N. Cellular responses to pollutants. Marine Pollution Bulletin 1985; 16: 134–139
   Web of Science ®Google Scholar
• Moore M. N. Cytochemical responses of the lysosomal system and NADPH-ferrihemoprotein reductase in molluscan digestive cells to environmental and experimental exposure to xenobiotics. Marine Ecology Progress Series 1988; 46: 81–89
   Web of Science ®Google Scholar
• Moore M. N., Livingstone D. R., Widdows J. Hydrocarbons in marine mollusks: biological effects and ecological consequences. Metabolism of Polynuclear Aromatic Hydrocarbons in the Aquatic Environment, U. Varanasi. CRC Press, Boca Raton, Florida 1989; 291–328
   Google Scholar
• Moore M. N., Pipe R. K., Farrer S. V. Lysosomal and microsomal responses to environmental factors in Littorina littorea from Sullom Voe. Marine Pollution Bulletin 1982; 13: 340–345
   Google Scholar
• Moore M. N., Livingstone D. R., Widdows J., Lowe D. M., Pipe R. K. Molecular, cellular and physiological effects of oil-derived hydrocarbons on molluscs and their use in impact assessment. Philosophical Transactions of the Royal Society of London 1987; B 316: 603–623
   Google Scholar
• Moore M. N., Livingstone D. R., Donkin P., Bayne B. L., Widdows J., Lowe D. M. Mixed function oxygenase and xenobiotic detoxication/toxication systems in bivalve molluscs. Helgoläander wiss Meeresunters 1980; 33: 278–291
   Google Scholar
• Morton J. E. Molluscs. Hutchinson University Library, London 1958
   Google Scholar
• Morgenstern R., DePierre J. W., Lind C., Guthenberg C., Mannervik B., Ernster L. Benzo‘a’pyrene quinones can be generated by lipid peroxidation and are conjugated with glutathione by glutathione S-transferase B from rat liver. Biochemical and Biophysical Research Communications 1981; 99: 682–690
   PubMed Web of Science ®Google Scholar
• Nash T. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Journal of Biological Chemistry 1953; 55: 416–422
   Google Scholar
• Nebert D. W., Gonzalez F. J. P450 genes: structure, evolution and regulation. Annual Review of Biochemistry 1987; 56: 945–993
   PubMed Web of Science ®Google Scholar
• Nelson D. R., Strobel H. W. Evolution of cytochromc P-450 proteins. Molecular Biology and Evolution 1987; 4: 572–593
   PubMed Web of Science ®Google Scholar
• Nott J. A., Moore M. N. Effects of polycyclic aromatic hydrocarbons on molluscan lysosomes and endoplasmic reticulum. Histochemical Journal 1987; 19: 357–368
   PubMedGoogle Scholar
• O'Brien P. J. Multiple mechanisms of metabolic activation of aromatic amine carcinogens. Free Radicals in Biology, W. A. Pryor. Academic Press, New York 1984; 289–321
   Google Scholar
• Okada S., Aikawa T. Cathepsin D-like proteinase in the mantle of the marine mussel, Mytilus edulis. Comparative Biochemistry and Physiology 1986; 84B: 333–341
   Google Scholar
• Owen G. Lysomes, peroxisomes and bivalves. Scientific Progress, Oxford 1972; 60: 299–318
   PubMed Web of Science ®Google Scholar
• Parry J. M., Kadhim M., Barnes W., Danford N. Assays of marine organisms for the presence of mutagenic and/or carcinogenic chemicals. Phyletic Approaches to Cancer, C. J. Dawe, J. C. Harshbarger, S. Kondo, T. Sugimura, S. Takayama. Japan Scientific Societies Press, Tokyo 1981; 141–166
   Google Scholar
• Payne J. F. Mixed function oxidases in marine organisms in relation to petroleum hydrocarbon metabolism and detection. Marine Pollution Bulletin 1977; 8: 112–116
   Google Scholar
• Payne J. F., Rahimtula A., Lim S. Metabolism of petroleum hydrocarbons by marine organisms: the potential of bivalve molluscs. 26th Annual. Meeting of the Canadian Federation of Biological Societies. 1983; Vol. 26, no.PA-235
   Google Scholar
• Quattrochi L. C., Lee R. F. Microsomal cytochromes P-450 from marine crabs. Comparative Biochemistry and Physiology 1984; 79C: 171–176
   Google Scholar
• Reed G. A. Co-oxidation of xenobiotics: lipid peroxyl derivatives as mediators of metabolism. Chemistry and Physics of Lipids 1987; 44: 127–148
   PubMedGoogle Scholar
• Rodrigues A. D., Gibson G. G., Ioannides C., Parke D. V. Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins. Biochemical Pharmacology 1987; 36: 4277–4281
   PubMed Web of Science ®Google Scholar
• Schenkman J. B., Sligar S. G., Cinti D. L. Substrate interaction with cytochrome P-450. Hepatic Cytochrome P-450 Monooxygenase System, J. B. Schenkman, D. Kupfer. Pergamon Press, Oxford 1982; 587–615
   Google Scholar
• Schlenk D., Buhler D. R. Cytochrome P-450 and phase II activities in the gumboot chiton Cryptochiton stelleri. Aquatic Toxicology 1988; 13: 167–182
   Web of Science ®Google Scholar
• Schwen R. J., Mannering G. J. Hepatic cytochrome P-450-dependent monooxygenase systems of the trout, frog and snake. III. Induction. Comparative Biochemistry and Physiology 1982; 71B: 445–453
   Google Scholar
• Srivastava K. C., Mustafa T. Formation of prostaglandins and other comparable products during aerobic and anaerobic metabolism of ‘1-14C’ arachidonic acid in the tissues of sea mussels, Mytilus edulis L. Molecular Physiology 1985; 8: 101–112
   Google Scholar
• Stegeman J. J. Mixed-function oxygenase studies in monitoring for effects of organic pollution. Rapports et Procès-Verbaux des Reunions Conseil International Pour L'Exploration de la Mer 1980; 179: 33–38
   Google Scholar
• Stegeman J. J. Benzo‘a’pyrene oxidation and microsomal enzyme activity in the mussel (Mytilus edulis) and other bivalve mollusc species from the Western North Atlantic. Marine Biology 1985; 89: 21–30
   Web of Science ®Google Scholar
• Stegeman J. J., Kloepper-Sams P. J. Cytochrome P-450 isozymes and monooxygenase activity in marine animals. Environmental Health Perspectives 1987; 71: 87–95
   PubMed Web of Science ®Google Scholar
• Suteau P. M., Narbonne J. F. Preliminary data on PAH metabolism in the marine mussel Mytilus galloprovincialis from Acrachon Bay, France. Marine Biology 1988; 98: 421–425
   Google Scholar
• Suteau P., Migaud M. L., Narbonne J. F. Sex and seasonal variations of PAH detoxication/toxication enzyme activities in the marine mussel Mytilus galloprovincialis. Marine Environemtnal Research 1985; 17: 152–153
   Google Scholar
• Suteau P., Migaud M. L., Daubeze M., Narbonne J. F. Comparative induction of drug metabolizing enzymes in whole mussel by several types of inducer. Marine Environmental Research 1988; 24: 119
   Google Scholar
• Takimoto Y., Ohshima M., Miyamoto J. Comparative metabolism of fenitrothion in aquatic organisms. II. Metabolism in the freshwater snails, Cipangopalundina japonica and Physa acuta. Ecotoxicology and Environmental Safety 1987; 13: 118–125
   PubMedGoogle Scholar
• Trautman T. D., Gee S. J., Krieger R. I., Thongsinthusak T. Sensitive radioassay of microsomal O-demethylation of 14CH3O-or C3H3O-p-nitroanisole for comparative studies. Comparative Biochemistry and Physiology 1979; 63C: 33–339
   Google Scholar
• Ullrich V., Weber P. The O-dealkylation of 7-ethoxycoumarin by liver microsomes Hoppe-Seyler's Zeitschrift für. Physiological Chemistry 1972; 353: 1171–1177
   PubMedGoogle Scholar
• Vandermeulen J. H., Penrose W. R. Absence of aryl hydrocarbon hydroxylase (AHH) in three marine bivalves. Journal of the Fisheries Research Board of Canada 1978; 35: 643–647
   Google Scholar
• Viarengo A., Pertica M., Mancinelli G., Palmero S., Orunesu M. Isolation and biochemical characterization of the microsomal fraction from the digestive gland of mussel Mytilis galloprovincialis Lam. Comparative Biochemistry and Physiology 1986; 83C: 439–442
   Google Scholar
• Walton M. J., Pennock J. F. Some studies on the biosynthesis of ubiquinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. Biochemical Journal 1972; 127: 471–479
   PubMed Web of Science ®Google Scholar
• Waxman D. J. Rat hepatic cytochrome P-450: comparative study of multiple isozymic forms. Cytochrome P-450 Structure, Mechanism and Biochemistry, P. R. Ortiz de Montellano. Plenum Press, New York 1986; 525–539
   Google Scholar
• Wenning R. J., Di Guilio R. T. Microsomal enzyme activities, superoxide production, and antioxidant defenses in ribbed mussels (Geukensia demissa) and wedge clams (Rangia cuneata). Comparative Biochemistry and Physiology 1988a; 90C: 21–28
   Google Scholar
• Wenning R. J., Di Guilio R. T. The effects of paraquat on microsomal oxygen reduction and antioxidant defenses in ribbed mussels (Geukensia demissa) and wedge clams (Rangia cuneata). Marine Environmental Research 1988b; 24: 301–305
   Web of Science ®Google Scholar
• Wenning R. J., Di Guilio R. T., Gallagher E. P. Oxidant-mediated biochemical effects of paraquat in the ribbed mussel Geukensia demissa. Aquatic Toxicology 1988; 12: 157–170
   Web of Science ®Google Scholar
• Widdows J., Moore S. L., Clarke K. R., Donkin P. Uptake, tissue distribution and elimination of ‘1-14C’ naphthalene in the mussel Mytilus edulis. Marine Biology 1983; 76: 109–114
   Google Scholar
• Wiebel F. J., Leutz J. C., Diamond L., Gelboin H. V. Aryl hydrocarbon (benzo‘a’pyrene) hydroxylase in microsomes from rat tissues; differential inhibition and stimulation by benzoflavones and organic solvents. Archives of Biochemistry and Biophysics 1971; 144: 76–86
   Google Scholar
• Willis D. E., Addison R. F. Hydroxylation of biphenyl in vitro by tissue preparations of some marine organisms. Comparative and General Pharmacology 1974; 5: 77–81
   PubMedGoogle Scholar
• Winston G. W., Livingstone D. R., Lips F. (1988) Oxyradical production by microsomes from the marine mussel Mytilus edulis. Proceedings of the 2nd International Congress of Comparative Physiology and Biochemistry. August, 1988. Louisiana State University, Baton RougeUSA, No. 619
   Google Scholar
• Wong A. K. L., Cavalieri E., Rogan E. Dependence of benzo‘a’pyrene metabolic profile on the concentration of cumene hydroperoxide with uninduced induced rat liver microsomes. Biochemical Pharmacology 1986; 35: 1583–1588
   PubMedGoogle Scholar
• Yonge C. M., Thompson T. E. Living Marine Molluscs. Collins, London 1976
   Google Scholar