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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 12
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Original Article

The pharmacokinetics of pirtenidine in the rat and dog

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Pages 1349-1354 | Received 24 Nov 1988, Accepted 13 May 1989, Published online: 30 Sep 2009

References

  • Altman P. L., Dittmer D. S. Respiration and Circulation. Federation of the American Society of Experimental Biology, Bethesda, Maryland 1974
  • Calabrese E. J. Gastrointestinal and dermal absorption: interspecies differences. Drug Metabolism Reviews 1984; 15: 1013–1032
  • Greenslade D., Allen J. M., Franklin R. A. Disposition of ‘14C’-pirtenidine (Win 52172–2) in the rat and the dog. Xenobiotica 1989, (In press)
  • Shargel L., Yu B. C. A. Applied Biopharmaceutics and Pharmacokinetics2nd edn. Appleton-Century-Crofts, Norfolk, Connecticut 1985
  • US Patent No. 4, 598, 082, 1 July 1986
  • Wentland M. P., Bailey D. M., Powles R. G., Slee A. M., Sedlock D. M. The in vitro dental plaque inhibitory properties of a series of N-‘1-Alkyl-4-(1H)-pyridinylidene’ alkylamines. Journal of Medicinal Chemistry 1988; 31(10)2024–2027
  • Winrow M. J. Metabolic studies with radiolabelled chlorhexidine in animals and man. Journal of Periodontal Research 1973; 8(Suppl. 12)45–48

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