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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 11
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Original Article

Review Physiological pharmacokinetic modelling

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Pages 1241-1257 | Received 06 Oct 1989, Accepted 01 Mar 1990, Published online: 27 Aug 2009

References

  • Balant L. P. Binding of drug to blood components and renal elimination. Protein Binding and Drug Transport, J.-P. Tillement, E. Lindenlaub. F. K. Schattauer Verlag, Stuttgart 1986; 231–245
  • Balant L. P., Garrett E. R. Computer use in Pharmacokinetics. Drug Fate and Metabolism, E. R. Garrett, J. L. Hirtz. Marcel Dekker, Inc., New York 1983; Vol. 4: 1–150
  • Balant L. P., Dayer P., Fabre J. Consequence of renal insufficiency on the hepatic clearance of some drugs. International Journal of Clinical Pharmacology Research 1983; 3: 459–474
  • Balant L., Roseboom H., Gundert-Remy U. M. Pharmacokinetic criteria for drug research and development. Advances in Drug Research, B. Testa. Academic Press, London 1990; Vol. 19: 1–138
  • Bischoff K. B., Dedrick R. L. Thiopental pharmacokinetics. Journal of Pharmaceutical Sciences 1968; 57: 1347–1357
  • Boxenbaum H. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: extrapolation of data to benzodiazepines and phenytoin. Journal of Pharmacokinetics and Biopharmaceutics 1980; 8: 165–176
  • Boxenbaum H. Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics. Journal of Pharmacokinetics and Biopharmaceutics 1982; 10: 201–227
  • Boxenbaum H. Evolutionary biology, animal behavior, fourth-dimensional space, and the Raison d'Etre of drug metabolism and pharmacokinetics. Drug Metabolism Reviews 1983; 14: 1057–1097
  • Boxenbaum H. Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm. Drug Metabolism Reviews 1984; 15: 1071–1121
  • Gerlowski L. E., Jain R. K. Physiologically based pharmacokinetic modelling: principles and applications. Journal of Pharmaceutical Sciences 1983; 72: 1103–1127
  • Himmelstein K. J., Lutz R. J. A review of the applications of physiologically based pharmacokinetic modelling. Journal of Pharmacokinetics and Biopharmaceutics 1979; 7: 127–145
  • Jansen A. Influence of plasma protein binding kinetics on hepatic clearance assessed from a ‘tube’ model and a ‘well-stirred’ model. Journal of Pharmacokinetics and Biopharmaceutics 1981; 9: 15–25
  • Mordenti J. Man versus beast: Pharmacokinetic scaling in mammals. Journal of Pharmaceutical Sciences 1986; 75: 1028–1040
  • Nies A. S., Shand D. G., Wilkinson G. R. Altered hepatic blood flow and drug disposition. Clinical Pharmacokinetics 1976; 1: 135–155
  • Øie S., Tozer T. N. Effect of altered plasma protein binding on apparent volume of distribution. Journal of Pharmaceutical Sciences 1979; 68: 1203–1205
  • Pang K. S., Rowland M. Hepatic clearance of drugs I. Journal of Pharmacokinetics and Biopharmaceutics 1977 a; 5: 625–653
  • Pang K. S., Rowland M. Hepatic clearance of drugs II. Journal of Pharmacokinetics and Biopharmaceutics 1977 b; 5: 665–680
  • Rowland M. The influence of route of administration on drug availability. Journal of Pharmaceutical Sciences 1972; 61: 70–74
  • Rowland M. Physiologic pharmacokinetic models: relevance, experience and future trends. Drug Metabolism Reviews 1984; 15: 55–74
  • Rowland M. Physiologic pharmacokinetic models and interanimal species scaling. Pharmacology and Therapeutics 1985; 29: 49–68
  • Rowland M., Benet L. Z., Graham G. G. Clearance concept in pharmacokinetics. Journal of Pharmacokinetics and Biopharmaceutics 1973; 1: 123–126
  • Tozer T. N. Concepts basic to pharmacokinetics. Pharmacology and Therapeutics 1981; 12: 109–131
  • Vaughan D. P., Hope I. Application of recirculatory stochastic pharmacokinetic models: limitation of compartmental models. Journal of Pharmacokinetics and Biopharmaceutics 1979; 7: 207–225
  • Weisiger R. A. Non-equilibrium drug binding and hepatic drug removal. Protein Binding and Drug Transport, J.-P. Tillement, E. Lindenlaub. F. K. Schattauer Verlag, Stuttgart 1986; 293–310
  • Weiss M., Förster W. Pharmacokinetic models based on circulatory transport. European Journal of Clinical Pharmacology 1979; 16: 287–293
  • Westlake W. J. Problems associated with analysis of pharmacokinetic models. Journal of Pharmaceutical Sciences 1971; 60: 882–885
  • Wilkinson G. R. Clearance concepts in pharmacokinetics. Annual Review of Pharmacology 1975; 15: 11–27
  • Wilkinson G. R., Shand D. G. Commentary: A physiological approach to hepatic drug clearance. Clinical Pharmacology and Therapeutics 1975; 18: 377–390

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