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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 4
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Research Article

Metabolism of the glutathione conjugate of propachlor by in situ perfused kidneys and livers of rats

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Pages 375-383 | Received 27 Jun 1989, Accepted 20 Nov 1989, Published online: 22 Sep 2008

References

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  • Bakke J. E., Feil V. J., Price C. E. Replacement of a chlorine with a methylsulfonyl group in the metabolism of propachlor (2-chloro-N-isopropylacetanilide. Biomedical Mass Spectrometry 1976; 3: 226–229
  • Bakke J. E., Larsen G. L. Metabolism of 2-chloro-N-isopropylacetanilide in chickens. Chemosphere 1985; 14: 1749–1754
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  • Davison K. L., Bakke J. E., Larsen G. L. A kidney perfusion method for metabolism studies with chickens using propachlor as a model. Xenobiotica 1988; 18: 323–329
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  • Larsen G. L., Bakke J. E. Metabolism of mercapturic acid-pathway metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by gastrointestinal bacteria. Xenobiotica 1983; 13: 115–126
  • Lash L. H., Jones D. P. Uptake of the glutathione conjugate S-(1,2-dichlorovinyl)glutathione by renal basal-lateral membrane vesicles and isolated kidney cells. Molecular Pharmacology 1985; 28: 278–282
  • Pekas J. C., Larsen G. L., Feil V. J. Propachlor detoxification in the small intestine: cysteine conjugation. Journal of Toxicology and Environmental Health 1979; 5: 653–662

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