Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 8
30
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Absorption, distribution and excretion of lacidipine, a dihydropyridine calcium antagonist, in rat and dog

, , , &
Pages 765-777 | Received 08 Sep 1989, Accepted 07 Mar 1990, Published online: 27 Aug 2009

References

  • Asling J., Way E. L. Fundamentals of Drug Metabolism and Drug Disposition, B. N. La Du, H. G. Mandel, E. L. Way. Williams & Wilkins, Baltimore 1972; 94
  • Bäärnhielm C., Dahlbäck H., Skånberg I. ‘In vivo’ Pharmacokinetics of felodipine predicted from ‘in vitro’ studies in rat, dog and man. Acta Pharmacologica et Toxicologica 1986; 59: 113–122
  • Carpi C., Gaviraghi G., Semeraro C. GX 1048 (GR 43659X) a new dihydropyridine calcium antagonist with potent and long lasting antihypertensive action. British Journal of Pharmacology 1986; 89: 758P, (Proc. Suppl.)
  • Edgard B., Regardh C. G., Johnsson G., Johansson L., Lundborg P., Löfberg I., Rönn O. Felodipine kinetics in healthy men. Clinical Pharmacology and Therapeutics 1985; 38: 205–211
  • Higuchi S., Shiobara Y. Comparative pharmacokinetics of nicardipine hydrochloride, a new vasodilator, in various species. Xenobiotica 1980; 10(6)447–454
  • Higuchi S., Sasaki H., Shiobara Y., Sado T. Absorption, excretion and metabolism of a new dihydropyridine diester cerebral vasodilator in rats and dogs. Xenobiotica 1977; 7(8)469–479
  • Maruhn D., Siefert H. M., Weber H., Rämsch K., Suwelack D. Pharmacokinetics of nimodipine 1. Arzneimittel Forschung 1985; 35(II)1781–1786
  • Midgley I., Chasseaud L. F., Taylor I. W., Walmsley L. M., Fowkes A. G. Metabolism and pharmacokinetics of the dihydropyridine calcium antagonist, ryosidine, in man. Xenobiotica 1985; 15(11)965–977
  • Parinov V. J., Odinec A. G., Gilev A. P., Dubur G. J., Muceniece D. H., Ozol J. J., Shatz V. D., Gavars M. P., Vigante B. A. Pharmacokinetics and metabolism of ryodipine in rats. Arzneimittel Forschung 1985; 35(I)808–813
  • Suwelack D., Weber H., Maruhn D. Pharmacokinetics of nimodipine II,. Arzneimittel Forschung 1985; 35(II)1787–1794
  • Takata Y., Kato H. Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. Arzneimittel Forschung 1986; 36(II)1464–1471
  • Tokuma Y., Fujiwara T., Noguchi H. Absorption, distribution and excretion of nilvadipine, a new dihydropyridine calcium antagonist in rats and dogs. Xenobiotica 1987; 17: 1341–1349
  • Tokuma Y., Sekiguchi M., Niwa T., Noguchi H. Pharmacokinetics of nilvadipine, a new dihydropyridine calcium antagonist, in mice, rats, rabbits and dogs. Xenobiotica 1988; 18: 21–28

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.