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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 3
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Research Article

A novel metabolite of strychnine, 22-hydroxystrychnine

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Pages 395-402 | Received 12 Apr 1990, Accepted 23 Oct 1990, Published online: 22 Sep 2008

References

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  • Craig D. A., Martin G. E. Proton double quantum and relayed proton double quantum coherence two-dimensional nmr mapping of proton-proton connectivity networks in natural products : a model study of strychnine. Journal of Natural Products 1986; 49: 456–465
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  • Oguri K., Tanimoto Y., Mishima M., Yoshimura H. Metabolic fate of strychnine in rats. Xenobiotica 1989; 19: 171–178
  • Pratt D. V., Hopkins P. B. Isolation and characterization of a stable simple enol. Journal of American Chemical Society 1987; 109: 5553–5554
  • Tanimoto Y., Ohkuma T., Oguri K., Yoshimura H. Species differences in metabolism of strychnine with liver microsomes of mice, rats, guinea pigs, rabbits and dogs. Journal of Pharmacobio-Dynamics 1990; 13: 136–141
  • Wolf C. R. Oxidation of foreign compounds at carbon atoms. Metabolic Basis of Detoxication, W. B. Jacoby, J. R. Bend, J. Caldwell. Academic Press, New York 1982; 5–28

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