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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 7
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Original Article

Pharmacokinetics and fate of 3H-trospectomycin sulphate, a novel aminocyclitol antibiotic, in male and female rats

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Pages 827-837 | Received 05 Dec 1989, Accepted 24 Jan 1991, Published online: 27 Aug 2009

References

  • Constable D. A., Dring L. G., Jones J. R. Synthesis of both 14C- and 3H-labelled trospectomycin and the assessment of their utility in biological studies. Journal of Labelled Compounds and Radiopharmaceuticals 1990; 28: 763–769
  • Cox J. W., Dring L. G., Ginsberg L. C., Larson P. G., Ulrich R. G. Distribution and disposition of trospectomycin sulfate in rat, rat perfused liver and cultured rat hepatocytes. Drug Metabolism and Disposition 1990; 18: 726–731
  • Metzler C. M., Weiner D. NONLIN84 User's Guide. Statistical Consultants. Inc, Edgewood, KYUSA 1984, Version VO2
  • Zurenko G. E., Ford C. W., Novak E. Trospectomycin, a novel spectinomycin analogue: Antibacterial activity and preliminary human pharmacokinetics. Drugs, Experimental Clinical Research 1988; 14: 403–409

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