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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 7
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Original Article

Protooncogene expression in rat liver by polychlorinated biphenyls (PCB)

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Pages 945-960 | Received 21 Jan 1991, Accepted 14 Mar 1991, Published online: 27 Aug 2009

References

  • Andersen P. R., Devare S. G., Tronick S. R., Ellis R. W., Aaronson S. A., Scolnick E. M. Generation of BALB-MuSV and Ha-MuSV by type C virus transduction of homologous transforming genes from different species. Cell 1981a; 26: 129–134
  • Anderson P. R., Tronick S. R., Aaronson S. A. Structural organization and biological activity of molecular clones of the integrated genome of a BALB/c mouse sarcoma virus (BALB-MSV). Journal of Virology 1981b; 40: 431–439
  • Bannasch P. Preneoplastic lesions as end points in carcinogenicity testing. Carcinogenesis 1986; 7: 689–695
  • Baumann M., Deml E., Schäffer E., Greim H. Effects of polychlorinated biphenyk at low dose levels in rats. Archives of Environmental Contamination and Toxicology 1983; 12: 509–515
  • Beer D. G., Schwarz M., Sawada N., Pitot H. C. Expression of H-ras and c-myc protooncogenes in isolated γ-glutamyl transpeptidase-positive rat hepatocytes and in hepatocel-lular carcinomas induced by diethylnitrosamine. Cancer Research 1986; 46: 2435–2441
  • Beer D. G., Neveu M. J., Paul D. L., Rapp U. R., Pitot H. C. Expression of the c-raf protooncogene, γ-glutamyltranspeptidase, and gap junctions protein in rat liver neoplasms. Cancer Research 1988; 48: 1610–1617
  • Bishop J. M. Cellular oncogenes and retroviruses. Annual Review of Biochemistry 1983; 52: 301–354
  • Borek C., Guernsey D. L., Ong A., Edelman I. S. Critical role played by thyroid hormone in induction of neoplastic transformation by chemical carcinogens in tissue culture. Proceedings of the National Academy of Sciences, USA 1983; 80: 5749–5752
  • Bos J. L. The ras gene family and human carcinogenesis. Mutation Research 1988; 195: 255–271
  • Buick R. N., Pollack M. N. Perspectives on clonogenic tumor cells, stem cells and oncogenes. Cancer Research 1984; 44: 4909–4918
  • Burgering B. M. T., Snijders A. J., Maassen A., Van DER Eb A. J., Bos J. L. Possible involvement of normal p21 H-ras in insulin/insulinlike growth factor 1 signal transduction pathway. Molecular and Cellular Biology 1989; 9: 4312–4322
  • Chirgwin J. M., Przybyla A. E., MacDonald R. J., Rutter W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonudeases. Biochemistry 1979; 18: 5294–5299
  • Deml E., Oesterle D. Enhancing effect of coadministration of polychlorinated biphenyls and diethylnitrosamine on enzyme-altered islands induced by diethylnitrosamine in rat liver. Carcinogenesis 1986; 7: 1697–1700
  • Denison M. S., Fisher J. M., Whitlock J. P., Jr. Inducible, receptor-dependent protein-DNA interactions at a dioxine-responsive transcriptional enhancer. Proceedings of the National Academy of Sciences, USA 1988; 85: 2528–2532
  • Donner L., Fedele L. A., Garon C. F., Anderson S. J., Sherr C. J. McDonough feline sarcoma virus: characterization of the molecularly cloned provirus and its feline oncogene (v-fms). Journal of Virology 1982; 41: 489–500
  • Farber E. Carcinogenesis-cellular evolution as a unifying thread: presidential address. Cancer Research 1973; 33: 2537–2550
  • Farber E. The sequencial analysis of liver cancer induction. Biochimica et Biophysica Acta 1980; 605: 149–165
  • Farber E., Cameron R. The sequential analysis of cancer development. Advances in Cancer Research 1980; 31: 125–226
  • Galand P., Jacobovitz D., Alexandre K. Immunohistochemical detection of c-Ha-ras oncogene p21 product in pre neoplastic and neoplastic lesions during hepatocarcinogenesis in rats. International Journal of Cancer 1988; 41: 155–161
  • Garthoff L. K., Friedmann L., Farber T. M., Locke K. K., Sobotka T. J., Green S., Hurley N. E., Peters E. L., Story G. E., Moreland F. M., Graham C. H., Keys J. E., Taylor M. J., Scalera J. V., Rothlein J. E., Marks E. M., Cerra F. E., Rodi S. B., Spopn E. M. Biochemical and cytogenetic effects in rats caused by short-term ingestion of aroclor 1254 or firemaster BP6. Journal of Toxicology and Environmental Health 1977; 3: 769–796
  • Goyette M., Petropoulos C. J., Shank P. R., Fausto N. Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver. Molecular and Cellular Biology 1984; 4: 1493–1498
  • Hinton D. E., Glaumann H., Trump B. F. Studies on the cellular toxicity of polychlorinated biphenyls (PCB). Virchows Archiv, B, Cell Pathology 1978; 27: 279–306
  • Hiwasa T., Sakiyama S. Increase in the synthesis of a Mr, 32.000 protein in BALB/c353 cells after treatment with tumor promotors, chemical carcinogens, metal salts, and heat shock. Cancer Research 1986; 46: 2474–2481
  • Hsiao W.-L., Housey G. M., Johnson M. D., Weinstein I. B. Cells that overproduce protein kinase C are more susceptible to transformation by an activated H-ras oncogene. Molecular and Cellular Biology 1989; 9: 2641–2647
  • Hsieh L. L., Hsiao W.-L., Peraino C., Maronpot R. R., Weinstein I. B. Expression of retroviral sequences and oncogenes in rat liver tumors induced by diethylnitrosamine. Cancer Research 1987; 47: 3421–3427
  • Ishikawa F., Takaku F., Hayashi K., Nagao M., Sugimura T. Activation of rat c-raf during transformation of hepatocellular carcinoma DNA. Proceedings of the National Academy of Sciences, USA 1986; 83: 3209–3212
  • Jenke H.-S. Polychlorinated biphenyls interfere with the regulation of hydroxymethylglutaryl-coenzyme A reductase activity in rat liver via enzyme—lipid interaction and at the transcriptional level. Biochimica et Biophysica Acta 1985; 837: 85–93
  • Jenke H.-S., Löwel M., Berndt J. Modes of action and combination effects of polychlorinated biphenyls and hexachlorocyclohexane on the regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. Chemico-Biological Interactions 1988; 65: 175–186
  • Kannan N., Tanabe S., Tatsukawa R. Potentially hazardous residues of non-ortho chlorine substituted coplanar PCBs in human adipose tissue. Archives of Environmental Health 1988; 43: 11–14
  • Kimbrough R. D. Halogenated Biphenyls, Terphenyls, Naphthalens, Dibenzodioxins and Related Compounds. Elsevier North-Holland, New York 1980
  • Kimbrough R. D. Human health effects of polychlorinated biphenyls (PCBs) and poly-brominated biphenyls (PBBs). Annual Review of Pharmacology and Toxicology 1987; 27: 87–111
  • Kitamura N., Kitamura A., Toyoshima K., Hirayama Y., Yoshida M. Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus. Nature 1982; 297: 205–208
  • Kobush A.-B., Fischer G., Bock K. W. Tumor-promoting activity and cytotoxicity of 3,4,3′,4′-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci. Journal of Cancer Research and Clinical Oncology 1989; 115: 247–252
  • Korach K. S., Sarver P., Chae K., McLachlan A., McKinney J. D. Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes. Molecular Pharmacology 1988; 33: 120–126
  • Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
  • Land H., Parada L. F., Weinberg R. A. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983a; 304: 596–602
  • Land H., Parada L. F., Weinberg R. A. Cellular oncogenes and multistep carcinogenesis. Science 1983b; 222: 771–778
  • Maniatis T., Fritsch E. F., Sambrook J. Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 1982
  • McKinney J., Fannin R., Jordan S., Chae K., Rickenbacheh U., Pedersen L. Polychlorinated biphenyls and related compound interactions with specific binding sites for thyroxine in rat liver nuclear extracts. Journal of Medicinal Chemistry 1987; 30: 79–86
  • McKnight G. S., Palmiter R. D. Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct. Journal of Biological Chemistry 1979; 254: 9050–9058
  • Mölders H., Defesche J., Müller D., Bonner T. I., Rapp U. R., Müller R. Integration of transected LTR sequences into the c-raf proto-oncogene: activation by promotor insertion. EMBO Journal 1985; 4: 693–698
  • Moos M., Gallwitz D. Structure of two human β-actin-related processed genes one of which is located next to a simple repetitive sequence. EMBO Journal 1983; 2: 757–761
  • Morrison D. K., Kaplan D. R., Escobedo J. A., Rapp U. R., Roberts T. M., Williams L. T. Direct activation of the serine/threonine kinase activity of raf-1 through thyrosine phosphorylation by the PDGF-receptor. Cell 1989; 58: 649–657
  • Moser G. J., Smart R. C. Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenssis 1989; 10: 851–856
  • Mulligan R. C., Berg P. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proceedings of the National Academy of Sciences, USA 1981; 78: 2072–2076
  • Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature 1984; 308: 693–698
  • Norback D. H., Weltmann R. H. Polychlorinated biphenyl induction of hepatocellular carcinoma in the Sprague—Dawley rat. Environmental Health Perspectives 1985; 60: 97–105
  • Oesterle D., Deml E. Promoting effect of polychlorinated biphenyls on development of enzyme-altered islands in livers of weanling and adult rats. Journal of Cancer Research and Clinical Oncology 1983; 150: 141–147
  • Osborne T. F., Gil G., Brown M. S., Kowal R. C., Goldstein J. L. Identification of promotor elements required for in vitro transcription hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. Proceedings of the National Academy of Sciences, USA 1987; 84: 3614–3618
  • Porsch-Hällström I., Blanck A., Eriksson L. C., Gustafsson J.-A. Expression of the c-myc, c-fos and c-rasHa protooncogenes during sex-differentiated rat liver carcinogenesis in the resistant hepatocyte model. Carcinogenesis 1989; 10: 1793–1800
  • Preston B. D., van Miller J. P., Moore R. W., Allen J. R. Promoting effect of polychlorinated biphenyls (aroclor 1254) and polychlorinated dibenzofurane-free Aroclor 1254 on diethylnitrosamine induced tumorigenesis in the rat. Journal of the National Cancer Institute 1981; 66: 509–515
  • Rapp U. R., Goldsborough M. D., Mark G. E., Bonner T. I., Groffen J., Reynolds F. H., Jr, Stephenson J. R. Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus. Proceedings of the National Academy of Sciences, USA 1983; 80: 4218–4222
  • Rapp U. R., Cleveland J. J., Bonner T. I., Storm S. M. The raf oncogenes. The Oncogene Handbook, E. P. Reddy, A. M. Skalka, T. Curran. Elsevier. 1988; 213–253, chapter 14
  • Ratner L., Josephs S. F., Jarrett R., Reitz M. S., Wong-Staal F. Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucleic Acids Research 1985; 13: 5007–5018
  • Reddy E. P., Smith M. J., Srinivasan A. Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other one gene products with tyrosine-specific kinase activity. Proceedings of the National Academy of Sciences, USA 1983; 80: 3623–3627
  • Reymond C. D., Gomer R. H., Nellen W., Theibert A., Devreotes P., Firtel R. A. Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants. Nature 1986; 323: 340–343
  • Rigby P. W. J., Dieckmann R., Rhodes C., Berg P. Labeling of deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. Journal of Molecular Biology 1977; 113: 237–251
  • Schulte-Herrmann R., Timmermann-Trosiener I. Aberrant expression of adaption to phenobarbital may cause selective growth of foci of altered cells in rat liver. International agency for research on cancer. IARC Scientific Publications No. 56, Lyon 1984; 67–76
  • Sistonen L., Höltlä E., Mäkelä T. P., Keski-Oja J., Alitalo K. The cellular response to induction of the p21c-Ha-ras oncoprotein includes stimulation of jun gene expression. EMBO Journal 1989; 8: 815–822
  • Tanaka T., Slamon D. J., Battifora H., Cline M. J. Expression of p21 ras oncoproteins in human cancers. Cancer Research 1986; 46: 1465–1470
  • Thiele G. J., Deutsch L. A., Israel M. A. The expression of multiple proto-oncogenes is differentially regulated during retmoic acid induced maturation of human neuroblastoma cell lines. Oncogene 1988; 3: 281–288
  • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences, USA 1979; 76: 4350–4354
  • Traber P. G., Chianale J., Florence R., Kim K., Wojcik E., Gumucio J. J. Expression of cytochrome P450b and P450e genes in small intestine mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides. Journal of Biological Chemistry 1988; 263: 9449–9455
  • Van Beveren C., van Straaten F., Galleshaw J. A., Verma I. M. Nucleotide sequence of the genome of a murine sarcoma virus. Cell 1981; 27: 97–108
  • Van DE Vijver M., van DE Bersselaar R., Deville P., Cornelisse C., Peterse J., Nusse R. Amplification of the neu (c-erbB-2) oncogene in human mammary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene. Molecular and Cellular Biology 1987; 7: 2019–2023
  • Venneström B., Fanshier L., Moscovici C., Bishop J. M. Molecular cloning of the avian erythrobiastosis virus genome and recovery of oncogenic virus by transfection. of chicken cells. Journal of Virology 1980; 36: 575–585
  • Wang J. Y. J., Ledley F., Goff S., Lee R., Groner Y., Baltimore D. The mouse c-abl locus: molecular cloning and characterization. Cell 1984; 36: 349–356
  • Weinberger C., Thompson C. C., Ong E. S., Lebo R., Gruol D. J., Evans R. M. The c-erb-A gene encodes a thyroid hormone receptor. Nature 1986; 324: 641–646
  • Weinstein I. B. Growth factors, oncogenes, and multistage carcinogenesis. Journal of Cellular Biochemistry 1987; 33: 213–224
  • Weinstein I. B. The origins of human cancer: Molecular mechanism of carcinogenesis and their implications for cancer prevention and treatment. Twenty-seventh G. A. H. Clowes memorial award lecture. Cancer Research 1988; 48: 4135–4143
  • Whitlock J. P., Jr. The regulation of gene expression by 2,3,7,8-tetrachlordibenzo-p-dioxin. Pharmacological Review 1987; 39: 147–161
  • Young S., Parker P. J., Ullrich A. M., Stabel S. Down-regulation of protein kinase C is due to an increased rate of degradation. Biochemical Journal 1987; 244: 775–779

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