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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 10
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Research Article

In vitro transformation of dithiopyr by rat liver enzymes: Conversion of methylthioesters to acids by oxygenases

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Pages 1265-1271 | Received 25 Nov 1990, Accepted 12 Apr 1991, Published online: 22 Sep 2008

References

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  • Feng P. C. C., Wratten S. J. In vitro oxidation of 2,6-diethylaniline by rat liver microsomal enzymes. Journal of Agricultural and Food Chemistry 1987; 35: 491–496
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  • Heymann E. Carboxylesterases and amidases. Enzymatic Basis of Detoxication, W. B. Jakoby. Academic Press, New York 1980; vol. 2: 291–323
  • Lee L. F. 2,6-Substituted pyridine compounds. US Patent. 4,692,184, 1987
  • Mehrsheikh M. E., Clizbe L. A., Singh H., Purdum W. R. Synthesis of 13C-enriched and 14C-labelled dithiopyr. Journal of Labelled Compounds and Radiopharmaceuticals 1990; 28: 437–443
  • Solsten R. T., Fujiwara H., Logusch E. W. Chromatography/negative ion mass spectrometry in studies of herbicide metabolism. Liquid Chromatography/Mass Spectrometry, Application in Agricultural, Pharmaceutical, and Environmental Chemistry, M. A. Brown. ACS Symposium Series 420, American Chemical Society, Washington, DC 1990; 92–122
  • Tynes R. E., Hodgson E. Magnitude of involvement of the mammalian flavin-containing monooxygenase in the microsomal oxidation of pesticides. Journal of Agricultural and Food Chemistry 1985; 33: 471–479
  • Ziegler D. M. Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity. Trends in Pharmacological Sciences 1990; 11: 321–324

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