Maintenance of monooxygenase activities and detection of cytochrome P-450-mediated cytotoxicity in Mongolian gerbil hepatocyte cultures

References

• Aitio A. A simple and sensitive assay of 7-ethoxycoumarin deethylation. Analytical Biochemitry 1978; 85: 488–491
   PubMed Web of Science ®Google Scholar
• Blaich G., Gottlicher M., Cikryt P., Metzler M. Induction of P450 isoenzyme activites in Syrian golden hamster liver compared to rat liver as probed by the rate of 7-alkoxyresorufin O-dealkylation. Chemico-Biological Interactions 1988; 67: 129–138
   PubMed Web of Science ®Google Scholar
• Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding. Analytical Biochemistry 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Burke M. D., Thompson S., Elcombe C. R., Halpert J., Haaparanta T., Mayer R. T. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochrome P450. Biochemical Pharmacology 1985; 34: 3337–3345
   PubMed Web of Science ®Google Scholar
• Cai Z., Mehendale H. M. Lethal effects of CCI4 and its metabolism by Mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex. Toxicology and Applied Pharmacology 1990; 104: 511–520
   PubMed Web of Science ®Google Scholar
• Creaven P. J., Parke D. V., Williams R. T. A spectrofluorimetric study of the 7- hydroxylation of coumarin by liver microsomes. Biochemical Journal 1965; 96: 390–398
   PubMed Web of Science ®Google Scholar
• Crouch L. S., Ebel R. E. Benzo[a]pyrene metabolism in the Mongolian gerbil: influence of chlordecone and mirex induction. Xenobiotica 1987; 17: 859–867
   PubMed Web of Science ®Google Scholar
• Denizot F., Lang R. Rapid colorimetric assay for cell growth and survival. Journal of Immunological Methods 1986; 89: 271–277
   PubMed Web of Science ®Google Scholar
• De Perez O. A., De Ferreyra E. C., Bernacchi A. S., Villarruel M. C., De Fenos O. M., Castro J. A. Carbon tetrachloride-induced liver cell injury in the Mongolian gerbil (Meriones unguicalatus). Comparative Biochemistry and Physiology 1989; 94C: 357–364
   Google Scholar
• Dominguez K., Fentem J. H., Garle M. J., Fry J. R. Comparison of Mongolian gerbil and rat hepatic microsomal monooxygenase activities: high coumarin 7-hydroxylase activity in the gerbil. Biochemical Pharmacology 1990; 39: 1629–1631
   PubMed Web of Science ®Google Scholar
• Ebel R. E., McGrath E. A. CCI4-hepatotoxicity in the Mongolian gerbil: influence of monooxygenase system induction. Toxicology Letters 1984; 22: 205–210
   PubMed Web of Science ®Google Scholar
• Estabrook R. W., Peterson J., Baron J., Hildebrandt A. The spectrophotometric measurement of turbid suspensions of cytochromes associated with drug metabolism. Methods in Pharmacology, C. F. Chignell. Appleton-Century-Crofts, New York 1972; Vol. 2: 303–350
   Google Scholar
• Fentem J. H., Fry J. R. Comparison of the effects of inducers of cytochrome P-450 on Mongolian gerbil and rat hepatic microsomal monooxygenase activities. Xenobiotica 1991; 21: 895–904
   PubMed Web of Science ®Google Scholar
• Fentem J. H., Hammond A. H., Garle M. J., Fry J. R. Toxicity of coumarin and various methyl derivatives to cultures of rat hepatocytes and V79 cells. Toxicology In Vitro 1991, in press
   Web of Science ®Google Scholar
• Ginsberg M. D., Busto R. Rodent models of cerebral ischemia. Stroke 1989; 20: 1627–1642
   PubMed Web of Science ®Google Scholar
• Halpin R. A., Vyas K. P., El-Naggar S. F., Jerina D. M. Metabolism and hepatotoxicity of the naturally-occurring benzo[b]pyran Precocene I. Chemico-Biological Interactions 1984; 48: 297–315
   PubMed Web of Science ®Google Scholar
• Hammond A. H., Fry J. R. The in vivo induction of rat hepatic cytochrome P-450-dependent enzyme activities and their maintenance in culture. Biochemical Pharmacology 1990; 40: 637–642
   PubMed Web of Science ®Google Scholar
• Hammond A. H., Fry J. R. The use of hepatocytes cultured from inducer-treated rats in the detection of cytochrome P-450-mediated cytotoxicity. Toxicology In Vitro 1991; 5: 133–137
   PubMed Web of Science ®Google Scholar
• Houston T. E., Mutter L. C., Blanke R. V., Guzelian P. S. Chlordecone alcohol formation in the Mongolian gerbil (Meriones unguiculatus): a model for human metabolism of chlordecone (kepone). Fundamental and Applied Toxicology 1981; 1: 293–298
   PubMedGoogle Scholar
• Hsia M. T. S., Grossman S., Schrankel K. R. Hepatotoxicity of the anti-juvenile hormone Precocene II and the generation of dihydrodiol metabolites. Chemico-Biological Interactions 1981; 37: 265–277
   PubMed Web of Science ®Google Scholar
• Kahn K. The natural course of experimental cerebral infarction in the gerbil. Neurology 1972; 22: 510–515
   PubMed Web of Science ®Google Scholar
• Karpiak S. E., Tagliavia A., Wakade C. G. Animal models for the study of drugs in ischemic stroke. Annual Review of Pharmacology and Toxicology 1989; 29: 403–414
   PubMed Web of Science ®Google Scholar
• Lake B. G., Gray T. J. B., Evans J. G., Lewis D. F. V., Beamand J. A., Hue K. L. Studies on the mechanism of coumarin-induced toxicity in rat hepatocytes: comparison with dihy-drocoumarin and other coumarin metabolites. Toxicology and Applied Pharmacology 1989; 97: 311–323
   PubMed Web of Science ®Google Scholar
• Levine S., Sohn D. Cerebral ischemia in infant and adult gerbils. Archives of Pathology 1969; 87: 315–317
   PubMedGoogle Scholar
• Mayer R. T., Jermyn J. W., Burke M. D., Prough R. A. Methoxyresorufin as a substrate for fluorometric assay of insect microsomal O-dealkylases. Pesticide Biochemistry and Physiology 1977; 7: 349–354
   Web of Science ®Google Scholar
• Nebert D. W., Gonzalez F. J. P-450 genes: structure, evolution and regulation. Annual Review of Biochemistry 1987; 56: 945–993
   PubMed Web of Science ®Google Scholar
• Pohl R. J., Fouts J. R. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Analytical Biochemistry 1980; 107: 150–155
   PubMed Web of Science ®Google Scholar
• Prough R. A., Burke M. D., Mayer R. T. Direct fluorometric methods for measuring mixed-function oxidase activity. Methods in Enzymology, S. Fleischer, L. Packer. Academic Press, New York 1978; Vol. 52: 372–377
   Google Scholar
• Reese J. A., Byard J. L. Isolation and culture of adult hepatocytes from liver biopsies. In Vitro 1981; 17: 935–940
   PubMedGoogle Scholar
• Reik L. M., Levin W., Ryan D. E., Maines S. L., Thomas P. E. Monoclonal antibodies distinguish among isozymes of the cytochrome P-450b subfamily. Archives of Biochemistry and Biophysics 1985; 242: 365–382
   PubMed Web of Science ®Google Scholar
• Ullrich V., Weber P. The O-dealkylation of 7-ethoxycoumarin by liver microsomes. Hoppe-Seylers Zeitschrift für Physiologische Chemie 1972; 353: 1171–1177
   PubMedGoogle Scholar
• Vlasuk G. P., Ghrayeb J., Ryan D. E., Reik L., Thomas P. E., Levin W., Walz F. G., Jr. Multiplicity, strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes. Biochemistry 1982; 21: 789–798
   PubMed Web of Science ®Google Scholar
• Walz F. G., Jr, Vlasuk G. P., Steggles A. W. Species differences in cytochrome P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats. Biochemistry 1983; 22: 1547–1556
   PubMed Web of Science ®Google Scholar