Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 11
Submit an article Journal homepage
18
Views
9
CrossRef citations to date
0
Altmetric
Research Article

The metabolites of chlorpromazine N-oxide in rat bile

T. J. Jaworski College of Pharmacy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N 0W0
,
E. M. Hawes College of Pharmacy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N 0W0
,
J. W. Hubbard College of Pharmacy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N 0W0
,
G. McKay College of Pharmacy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N 0W0
&
K. K. Midha College of Pharmacy, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, S7N 0W0
Pages 1451-1459 | Received 01 Nov 1990, Accepted 22 May 1991, Published online: 22 Sep 2008

References

  • Bickel M. H. The pharmacology and biochemistry of N-oxides. Pharmacological Reviews 1969; 21: 325–355
  • Dajani R. M., Gorrod J. W., Beckett A. H. In vitro hepatic and extra-hepatic reduction of (—)-nicotine-1′-N-oxide in rats. Biochemical Pharmacology 1975a; 24: 109–117
  • Dajani R. M., Gorrod J. W., Beckett A. H. Reduction in vivo of (—)-nicotine-1′-N-oxide by germ-free and conventional rats. Biochemical Pharmacology 1975b; 24: 648–650
  • Hawes E. M., Jaworski T. J., Midha K. K., McKay G., Hubbard J. W., Korchinski E. D. In vivo metabolism of N-oxides. N-Oxidation of Drugs, Biochemistry, Pharmacology, Toxicology, P. Hlavica, L. A. Damani. Chapman & Hall, London 1991; 263–286
  • Jaworski T. J., Hawes E. M., McKay G., Midha K. K. The metabolism of chlorpromazine N-oxide in the rat. Xenobiotica 1988; 18: 1439–1447
  • Jaworski T. J., Hawes E. M., McKay G., Midha K. K. The metabolism of chlorpromazine N-oxide in man and dog. Xenobiotica 1990; 20: 107–115
  • Jenner P. The role of nitrogen oxidation in the excretion of drugs and foreign compounds. Xenobiotica 1971; 1: 399–418
  • Lambert R. Surgery of the Digestive System in the Rat. Charles C. Thomas, Springfield, Illinois 1965

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.