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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 2
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Research Article

Study on the metabolism of racemic prolintane and its optically pure enantiomers

G. Rücker Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, D-5300, Bonn 1, Germany
,
M. Neugebauer Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, D-5300, Bonn 1, Germany
&
D. Zhong Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, D-5300, Bonn 1, Germany
Pages 143-152 | Received 14 Mar 1991, Accepted 18 Oct 1991, Published online: 22 Sep 2008

References

  • Bonse G., Metzler M. Biotransformation organischer Fremdsubstanzen. Georg Thieme Verlag, Stuttgart 1978; 3
  • Rücker G., Neugebauer M., Zhong D. Synthese einiger Metaboliten und der Enantiomeren des Prolintans. Archiv der Pharmazie 1992; 325: 47–52
  • Testa B., Jenner P. Drug Metabolism. Marcel Dekker, New York/Basel 1976; 16
  • Yoshihara S., Yoshimura H. Metabolism of drugs. LXXVI. The metabolic fate of prolintane in rabbits. Chemical and Pharmaceutical Bulletin 1972; 20: 1906–1912
  • Yoshihara S., Yoshimura H. Metabolism of drugs. LXXXI. Further studies on metabolism of pronlintane in rabbits. Chemical and Pharmaceutical Bulletin 1974a; 22: 714–717
  • Yoshihara S., Yoshimura H. Metabolism of prolintane in rats and the effect of prolitane metabolites on general activities in mice. Xenobiotica 1974b; 4: 529–535

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