Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 8
22
Views
6
CrossRef citations to date
0
Altmetric
Research Article

A new carbamazepine metabolite in uraemic filtrate

&
Pages 1029-1035 | Received 03 Aug 1991, Accepted 28 Oct 1991, Published online: 22 Sep 2008

References

  • Baker K. M., Csetenyi J., Frigerio A., Morselli P. L., Parravicini F., Pifferi G. 10,11-dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide, a metabolite of carbamazepine isolated from human and rat urine. Journal of Medicinal Chemistry 1973; 16: 703–705
  • Beyer C., Spiteller G. Verschleppung von Glucuroniden bei Gelfiltration in die ‘Mittelmolekülfraktion’. Hoope-Seyler's Zeitschrift für Physiologische Chemie 1991, In press
  • Borel C., Gupta M. P., Hostettmann K. Molluscicidal saponins from Swartzia simplex. Phytochemistry 1987; 26: 2685–2689
  • Eichelbaum M., Tomson T., Tybring G., Bertilsson L. Carbamazepine metabolism in man. Clinical Pharmacokinetics 1985; 10: 80–90
  • Faigle J. W., Brechbühler S., Feldmann K. F., Richter W. J. Die Biotransformation von Carbamazepin. Anfall, Verhalten, Schmerz, Birkmayer. Hans Huber, Bern 1976; 130–142
  • Fenselau C., Yellet L. Glucuronic acid, sulfate ester, and glutathione xenobiotic conjugates. Xenobiotic Conjugation Chemistry 1986; 7: 159–176
  • Frigerio A., Fanelli R., Biandrate P., Passerini G., Morselli P. L., Garattini S. Mass spectrometric characterization of carbamazepine-10,11-epoxide, a carbamazepine metabolite isolated from human urine. Journal of Pharmaceutical Sciences 1972; 61: 1144–1147
  • Frigerio A., Baker K. M., Morselli P. L. Gas chromatographic-mass spectrometric studies on carbamazepine. Advances in Biochemical Psychopharmacology 1973; 7: 125–134
  • Goenechea S., Hecke-Seibicke E. Beitrag zum Stoffwechsel von Carbamazepin. Zeitschrift für Klinische Chemie und Klinische Biochemie 1972; 10: 112–113
  • Golding B. T., Rickards R. W. The determination of molecular formulae of polyols by mass spectrometry of their trimethylsilyl ethers; the structure of the macrolide antibiotic filipin. Tetrahedron Letters 1964; 37: 2615–2621
  • Hanicki Z., Sarnecka-Keller M., Klein A., Slizowska K. Middle-sized ninhydrin-positive molecules in uraemic patients treated by repeated haemodialysis; I. preliminary characteristics. Clinica Chimica Acta 1974; 54: 47–54
  • Hanicki Z., Cichocki T., Sarnecka-Keller M., Klein A., Komorowska Z. Influence of middle-sized molecule aggregates from dialysate of uraemic patients on lymphocyte transformation in vitro. Nephron 1976; 17: 73–80
  • Klein A., Sarnecka-Keller M., Hanicki Z. Middle-sized ninhydrin-positive molecules in uraemic patients treated by repeated haemodialysis: II. Chief peptide constituents of the fraction. Clinica Chimica Acta 1978; 90: 7–11
  • Lertratanangkoon K., Horning M. G. Metabolism of carbamazepine. Drug Metabolism and Disposition 1982; 10: 1–10
  • Lynn R. K., Smith R. G., Thompson R. M., Deinzer M. L., Griffin D., Gerber N. Characterization of glucuronide metabolites of carbamazepine in human urine by gas chroma-tography and mass spectrometry. Drug Metabolism and Disposition 1978; 6: 494–501
  • Monti J. P., Gallice P., Crevat A., Muriasaco A. Identification by nuclear magnetic resonance and mass spectrometry of a glucuronic acid conjugate of O-hydroxybenzoic acid in normal urine and uraemic plasma. Clinical Chemistry 1985; 31: 1640–1643
  • Morselli P. L., Frigerio A. Metabolism and pharmacokinetics of carbamazepine. Drug Metabolism Reviews 1975; 4: 97–113
  • Navarro J., Touraine J., Corre C., Traeger J. Prolongation of skin allograft survival and inhibition of graft versus host reaction in rodents treated with ‘middle molecules’. Cellular Immunology 1977; 31: 349–354
  • Röhr U., Spiteller G., Tripier D. Isolierung und Strukturaufklärung von Peptiden der mittelmolekularen Fraktion aus urämischem Hämofiltrat. Liebigs Annalen der Chemie 1988; 1988: 881–884
  • Scheiffarth F., Weist F., Zicha L. Zum Nachweis von 5-Carbamyl-5H-dibenzo[b,f]azepin im Liquor cerebrospinalis mittels Dünnschichtchromatographie. Zeitschrift für Klinische Chemie 1966; 4: 68–70
  • Schindler W. U.S. Patent. 2, 948.718, 1961, Chemical Abstracts 1960 55 1671b
  • Von Unruh G. E., Köthe K. W., Eichelbaum M. Stable Isotopes. Proc. Third Int. Conf. Oak Brook, Illinois,May, 23–261979, E. R. Klein, P. D. Klein. Academic Press, New York, 453–462
  • Weist F. R., Zicha L. Thin-layer chromatographic studies on 5-carbamoyl-5H-dibenz[d,f]azepine in urine and cerebrospinal fluid. Arzneimittel-Forschung 1967; 17: 874–875

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.