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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 9-10
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Research Article

Co-induction of cytochrome P4504A1 and peroxisome proliferation: A causal or casual relationship?

Pages 1101-1109 | Received 05 Oct 1990, Accepted 06 Apr 1992, Published online: 22 Sep 2008

References

  • Bacher M., Gibson G.G. Chlorophenoxy acid herbicides induce microsomal cytochrome P450IVA1 (P452) in rat liver. Chemico-Biological Interactions 1988; 65: 145–156
  • Bains S.K., Gardiner S., Mannweiler K., Gillet D., Gibson G.G. Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P450 to the metabolism of lauric acid and arachidonic acid. Biochemical Pharmacology 1985; 34: 3221–3229
  • Barnett C.R., Gibson G.G., Wolf C.R., Flatt P.R., Ioannides C. Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes. Biochemical Journal 1990; 268: 765–769
  • Bronfman M., Inestrosa N.C., Leighton F. Fatty acid oxidation by human liver peroxisomes. Biochemical and Biophysical Research Communications 1979; 88: 1030–1036
  • Chomczynski P., Saachi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 1987; 162: 156–159
  • Cinti D.L., Moldeus P., Schenkman J.B. Kinetic parameters of drug-metabolising enzymes in Ca2+-sedimented microsomes from rat liver. Biochemical Pharmacology 1972; 21: 3249–3256
  • Earnshaw D., Dale J.W., Goldfarb P.S., Gibson G.G. Differential splicing in the 3′ non-coding region of rat cytochrome P452 (P450IVA1) mRNA. FEBS Letters 1988; 236: 357–361
  • Gibson G.G. Comparative aspects of the mammalian cytochrome P450IVA gene family. Xenobiotica 1989; 19: 1123–1148
  • Gibson G.G., Orton T.C., Tamburini P.P. Cytochrome P450 induction by clofibrate: purification and properties of a hepatic cytochrome P450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). Biochemical Journal 1982; 203: 161–168
  • Green S. Commentary, receptor-mediated mechanisms of peroxisome proliferators. Biochemical Pharmacology 1992; 43: 393–401
  • Hawkins J.M., Jones W.E., Bonner F.W., Gibson G.G. The effect of peroxisome proliferators on microsomal, peroxisomal and mitochondrial enzyme activities in the liver and kidney. Drug Metabolism Reviews 1987; 18: 441–515
  • Lalwani N.D., Fahl W.E., Reddy J.K. Detection of a nafenopin-binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidaemic compounds. Biochemical and Biophysical Research Communications 1983; 116: 388–393
  • Lock E.A., Mitchell A.M., Elcombe C.R. Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annual Review of Pharmacology an Toxicology 1989; 29: 145–163
  • Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Makowska J.M., Anders C., Goldfarb P.S., Bonner F.W., Gibson G.G. Characterisation of the hepatic responses to the short-term administration of ciprofibrate in several rat strains. Co-induction of microsomal cytochrome P450IVA1 and peroxisome proliferation. Biochemical Pharmacology 1990; 40: 1083–1093
  • Maniatis T., Fritsch E.F., Sambrook J. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory. 1982
  • Nilsson A., Prydz K., Rortveit T., Christiansen E.N. Studies on the interrelated stimulation of microsomal oxidation in rat liver with a partially hydrogenated fish oil diet. Biochimica et Biophysica Acta 1987; 920: 114–119
  • Parker G.L., Orton. Induction by oxyisobutyrates of hepatic and kidney microsomal cytochrome P450 with specificity towards hydroxylation of fatty acids. Biochemistry, Biophysics and Regulation of Cytochrome P450, J.A. Gustafsson, J. Carlstedt-Duke, A. Mode, J. Rafter. Elsevier/North Holland, Amsterdam 1980; 373
  • Reddy J.K., Lalwani N.D. Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidaemic drugs and industrial placticisers to humans. CRC Critical Reviews in Toxicology 1983; 12: 1–58
  • Reddy J.K., Azarnoff D.L., Hignite C.E. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 1980; 283: 397–398
  • Sharma R.K., Lake B.G., Foster J.R., Gibson G.G. Microsomal cytochrome P452 induction and peroxisome proliferation by hypolipidaemic agents in rat liver. A mechanistic inter-relationship. Biochemical Pharmacology 1988a; 37: 1193–1201
  • Sharma R.K., Lake B.G., Gibson C.G. Co-induction of microsomal cytochrome P452 and the peroxisomal fatty acid β-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate. Dose-response studies. Biochemical Pharmacology 1988b; 37: 1203–1206
  • Sharma R.K., Lake B.G., Makowski R., Bradshaw T., Earnshaw D., Dale J.W., Gibson G.G. Differential induction of peroxisomal and microsomal fatty acid oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P450 and implications for peroxisome proliferation. European Journal of Biochemistry 1989a; 184: 69–78
  • Sharma R.K., Doig M.V., Lewis D. F. V., Gibson G.G. Role of hepatic and renal cytochrome P450IVA1 in the metabolism of lipid substrates. Biochemical Pharmacology 1989b; 38: 3621–3629
  • Tamburini P.P., Masson H.A., Bains S.K., Makowski R., Morris B., Gibson G.G. Multiple forms of hepatic cytochrome P450: purification, characterisation and comparison of a novel clofibrate-induced isoenzyme with other major forms of cytochrome P450. European Journal of Biochemistry 1984; 139: 245–246
  • Warren J.R., Simmon V.F., Reddy J.K. Properties of peroxisome proliferators in the lymphocyte 3H-thymidine and Salmonella mutagenesis assay. Cancer Research 1980; 40: 36–41
  • White B.A., Bancroft F.C. Cytoplasmic dot hybridisation. Sample analysis of relative mRNA levels in multiple small cell or tissue samples. Journal of Biological Chemistry 1982; 257: 8569–8572
  • Wu H.Q., Masset-Brown J., Tweedie D.J., Milewich L., Frenkel R.A., Martin-Wixtrom C., Estabrook R.W., Prough R.A. Induction of microsomal NADPH-cytochrome P450 reductase and cytochrome P450IVA1 (P450LA) by dehydroepiandrosterone in rats: a possible peroxisome proliferator. Cancer Research 1989; 49: 2337–2343

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