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Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 1
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Research Article

Metabolism of (-)-6(S)-hydroxy-4(R)-(1-hydroxy-1-methylethyl)-1-cyclohexene-1-ethanol in rat and dog

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Pages 41-49 | Received 25 Jan 1991, Published online: 22 Sep 2008

References

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  • Gervasi P. G., Lippi A., Bellucci G., Marioni F., Luzzani F., Ventura P. Different GSH depletion in liver and lung of rats by CO/1408 and trans-sobrerol. Abstract Book, VIII Congress of the Italian Society of Toxicology. University of Bologna, Bologna 1989; 88
  • Leclerq P. A., Desiderio D. M., Jr. A laboratory procedure for the acetylation and permethylation of oligopeptides on the microgram scale. Analytical Letters 1971; 4: 305–316
  • Lippi A., Gervasi P. G., Bellucci G., Marioni F., Luzzani F., Ventura P. Effect of a terpenoid, (−)-6-hydroxy-4-(1-hydroxy-1-methylethyl)-1-cyclohexene-1-ethanol, on a drug-metabolizing enzymes and glutathione content in rat liver and lung. Xenobiotica 1989; 19: 823–832
  • Thompson R. H., Gerber N., Seibert R. A., Desiderio D. M. A rapid method for the mass spectrometric identification of glucuronides and other polar drug metabolites in permethylated rat bile. Drug Metabolism and Disposition 1973; 1: 489–505
  • Ventura P., Schiavi M., Serafini S., Selva A. Further studies of trans-sobrerol metabolism: rat, dog and human urine. Xenobiotica 1985; 15: 317–325
  • Ventura P., Pellegata R., Schiavi M., Serafini S. Biotransformation of trans-sobrerol. III. Metabolites of 8-hydroxycarvotanacetone in the rat. Xenobiotica 1986; 16: 317–323
  • Watabe T., Hiratsuka A., Ozawa N., Isobe M. A comparative study on the metabolism of d-limonene and 4-vinyl-cyclohex-1-ene by epatic microsomes. Xenobiotica 1981; 11: 333–344

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