Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 22, 1992 - Issue 5
13
Views
29
CrossRef citations to date
0
Altmetric
Research Article

Effects of arsenite on hepatic mixed-function oxidase activity in rats

, , , &
Pages 591-597 | Received 12 Apr 1990, Accepted 08 Nov 1991, Published online: 22 Sep 2008

References

  • Albores A., Cebrian M. E., Bach P. H., Connelly J. C., Hinton R. H., Bridges J. W. Sodium arsenite induced alterations in bilirubin excretion and heme metabolism. Journal of Biochemical Toxicology 1989; 4: 73–78
  • Burke M. D., Mayer R. T. Ethoxyresorufin: direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metabolism and Disposition 1974; 2: 583–588
  • Burke M. D., Mayer R. T. Differential effects of phenobarbital and 3-methylcholanthrene induction on the hepatic microsomal metabolism and cytochrome P-450-binding phenoxazone and homologous series of its n-alkyl ethers (alkoxyresorufins). Chemico-Biological Interactions 1983; 45: 243–258
  • Cebrian M. E., Albores A., Connelly J. C., Bridges J. W. Assessment of arsenic effects on cytosolic heme status using tryptophan pyrrolase as an index. Journal of Biochemical Toxicology 1988; 3: 77–86
  • Dickins M., Elcombe C. R., Malone S. J., Netter K. J., Bridges J. W. Further studies on the dissociation of the isosafrole metabolite-cytochrome P-450 complex. Biochemical Pharmacology 1979; 28: 231–238
  • Jeffery E., Kotake A., El-Azhary R., Mannering G. J. Effects of linoleic acid hydroperoxide on the hepatic monooxygenase systems of microsomes from untreated. phenobarbital-treated, and 3-methylcholanthrene-treated rats. Molecular Pharmacology 1977; 13: 415–425
  • Lowry O. H., Rosebrough N. J., Farr A. C., Randall R. J. Protein measurement with the Folin-phenol reagent. Journal of Biological Chemistry 1951; 103: 265–275
  • Lu A. Y. H., Stroebel H. W., Coon H. J. Properties of a solubilized form of the cytochrome P-450 containing mixed function oxidase of liver microsomes. Molecular Pharmacology 1970; 6: 213–220
  • Lui E. M. K., Lucier G. W. Hypophyseal regulation of cadmium-induced depression of the hepatic monooxygenase system in the rat. Molecular Pharmacology 1981; 20: 185–171
  • Nordenson I., Beckman L. Is the genotoxic effect of arsenic mediated by oxygen free radicals?. Human Heridity 1991; 41: 71–73
  • Omura T., Sato R. The carbon monooxide-binding pigment of liver microsomes. Journal of Biological Chemistry 1964; 239: 2370–2378
  • Penning W., Scoppa P. Degradation of cytochrome P-450 heme and lipid peroxidation in lead-poisoned rats. Biological Reactive Metabolites, Formation, Toxicity and Inactivation, D. J. Jollow, J. J. Kocsis, R. Snyder, H. Vainio. Plenum Press, New York 1977; 448–451
  • Sardana M. K., Drummond G. S., Sassa S., Kappas A. The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals. Pharmacology 1981; 23: 247–253
  • Ullrich V., Weber P. The O-dealkylation of 7-ethoxycoumarin by liver microsomes. A direct fluorometric test. Hoppe-Seyler's Zeitschrift für Physiologische Chemie 1972; 353: 1171–1177
  • Webb J. L. Comparison of SH reagents. Enzyme and Metabolic Inhibitors, J. L. Webb. Academic Press, New York 1966; vol. 3: 785–819
  • WHO/IARC. Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man: Some Metals and Metallic Compounds. WHO/IRAC, Lyon 1980; vol. 23: 39–141
  • Yañez L., Carrizales L., Zanatta M. T., Mejìa J. J., Batres L., Diaz-Barriga F. Arsenic-cadmium interaction in rats: toxic effects in the hearth and tissue metal shifts. Toxicology 1991; 67: 227–234

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.