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Xenobiotica
the fate of foreign compounds in biological systems
Volume 24, 1994 - Issue 11
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Original Article

Metabolism and disposition of 14C-granisetron in rat, dog and man after intravenous and oral dosing

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Pages 1119-1131 | Received 13 Jul 1994, Published online: 27 Aug 2009

References

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  • Cupissol D. R., Serrou B., Caubel M. The efficacy of granisetron as a prophylactic anti‐emetic and intervention agent in high‐dose cisplatin‐induced emesis. European Journal of Cancer 1990; 26(Suppl. 1)S23–27
  • Marty M. A comparison of granisetron as a single agent with conventional combination anti‐emetic therapies in the treatment of cytostatic‐induced emesis. The granisetron study group. European Journal of Cancer 1992; 28A(Suppl. 1)S12–16
  • Plosker G. L., Goa K. L. Granisetron: a review of its pharmacological properties and therapeutic use as an anti‐emetic. Drugs 1991; 42: 805–824
  • Sanger G. J., Nelson D. R. Selective and functional 5‐hydroxytryptamine‐3 receptor antagonism by BRL 43694 (granisetron). European Journal of Pharmacology 1989; 159: 113–124
  • Tomlinson P. W., Jeffery D. J., Filer C. W. A novel technique for assessment of biliary secretion and enterohepatic circulation in the unrestrained conscious rat. Xenobiotica 1981; 11: 863–870

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