References
- Al-Dabbagh S. G., Idle J. R., Smith R. L. Animal modelling of human polymorphic oxidation—the metabolism of debrisoquine and phenacetin in rat inbred strains. Journal of Pharmacy and Pharmacology 1981; 33: 161–164
- Barnhart J. W. The urinary excretion of dextromethorphan and three metabolites in dogs and humans. Toxicology and Applied Pharmacology 1980; 55: 43–48
- Boobis A. R., Seddon C. E., Davies D. S. Bufuralol 1′-hydroxylation activity of the rat—strain differences and effects of inhibitors. Biochemical Pharmacology 1986; 35: 2961–2965
- Char H., Kumar S., Patel S., Piemontese D., Iqbal K., Malick A. W., Salvador R. A., Behl C. R. Nasal delivery of [14C] dextromethorphan hydrochloride in rats: levels in plasma and brain. Journal of Pharmaceutical Sciences 1992; 81: 750–752
- Chen Z. R., Somogyi A. A., Bochner F. Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high-performance liquid chromatography with application to their disposition in man. Therapeutic Drug Monitoring 1990; 12: 97–104
- Guengerich F. P., Müller-Enoch D., Blair I. A. Oxidation of quinidine by human liver cytochrome P-450. Molecular Pharmacology 1986; 30: 287–295
- Jacqz-Aigrain E., Funck-Brentano C., Cresteil T. CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans. Pharmacogenetics 1993; 3: 197–204
- Kamm J. J., Taddeo A. B., Van Loon E. J. Metabolism and excretion of tritiated dextromethorphan by the rat. Journal of Pharmacology and Experimental Therapeutics 1967; 158: 437–444
- Kerry N. L., Somogyi A. A., Mikus G., Bochner F. Primary and secondary oxidative metabolism of dextromethorphan: in vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes. Biochemical Pharmacology 1993; 45: 833–839
- Kobayashi S., Murray S., Watson D., Sesardic D., Davies D. S., Boobis A. R. The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man. Biochemical Pharmacology 1989; 38: 2795–2799
- Kostfr A. S., Nieuwenhuis L., Frankhuijzen-Sierevogel A. C. Comparison of microsomal drug-metabolizing enzymes in 14 rat inbred strains. Biochemical Pharmacology 1989; 38: 759–765
- Küpfer A., Schmid B., Pfaff G. Pharmacogenetics of dextromethorphan O-demethylation in man. Xenobiotica 1986; 16: 421–433
- Larrey D., Amouyal G., Tinel M., Letteron P., Berson A., Labbe G., Pessayre D. Polymorphism of dextromethorphan oxidation in a French population. British Journal of Clinical Pharmacology 1987; 24: 676–679
- Matsunaga E., Zanger U. M., Hardwick J. P., Gelboin H. V., Meyer U. A., Gonzalez F. J. The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats. Biochemistry 1989; 28: 7349–7355
- Mikus G., Somogyi A. A., Bochner F., Eichelbaum M. Thebaine O-demethylation to oripavine: genetic differences between two rat strains. Xenobiotica 1991a; 21: 1501–1509
- Mikus G., Somogyi A. A., Bochner F., Eichelbaum M. Codeine O-demethylation: rat strain differences and the effects of inhibitors. Biochemical Pharmacology 1991b; 41: 757–762
- Parke D. V. The Biochemistry of Foreign Compounds. International Series of Monographs in Pure and Applied Biology/Biochemistry Division. Pergamon, Oxford 1968; Vol. 5: 83–87
- Pfaff G., Briegel P., Lamprecht I. Inter-individual variation in the metabolism of dextromethorphan. International Journal of Pharmaceutics 1983; 14: 173–189
- Schmid B., Bircher J., Preisig R., Küpfer A. Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation. Clinical Pharmacology and Therapeutics 1985; 38: 618–624
- Zysset T., Zeugin T., Küpfer A. In vivo and in vitro dextromethorphan metabolism in SD and DA rat: an animal model of the debrisoquine-type polymorphic oxidation in man. Biochemical Pharmacology 1988; 37: 3155–3160