Pharmacokinetics of barnidipine hydrochloride, a new dihydropyridine calcium channel blocker, in the rat, dog and human

References

• Ahr H. J., Krause H. P., Siefert H. M., Suwelack D., Weber H. Pharmacokinetics of nisoldipine, I. Absorption, concentration in plasma, and excretion after single administration of [14C]nisoldipine in rats, dogs, monkey, and swine. Arzneimittel-Forsh 1988; 38: 1093–1098
   PubMed Web of Science ®Google Scholar
• Bäärnhielm C., Dahlbäck H., Skånberg I. In vivo pharmacokinetics of felodipine predicted from in vitro studies in rat, dog and man. Acta Pharmacologica et Toxicologica 1986; 59: 113–122
   PubMedGoogle Scholar
• Edgar B., Regårdh C. G., Johnsson G., Johansson L., Lundborg P., Löfberg I., Ronn Ö. Felodipine kinetics in healthy men. Clinical and Pharmacological Therapeutics 1985; 38: 205–211
   PubMed Web of Science ®Google Scholar
• Faulkner J. K., McGibney D., Chasseaud L. F., Perry J. L., Taylor I. W. The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily. British Journal of Clinical Pharmacology 1986; 22: 21–25
   PubMed Web of Science ®Google Scholar
• Hashimoto K., Tsujimoto G., Motomura S., Teramura T., Takenaka T. Pharmacokinetics of mepirodipine (YM730) and its sustained release formulation in normal subjects. European Journal of Clinical Pharmacology 1989; 36(suppl.)A86
   Google Scholar
• Higuchi S., Shiobara Y. Comparative pharmacokinetics of nicardipine hydrochloride, a new vasodilator, in various species. Xenobiotica 1980; 10: 447–454
   PubMed Web of Science ®Google Scholar
• Humphrey M. J. Pharmacokinetic studies in the selection of new drugs—a case history on dihydropyridine calcium channel blockers. Proceedings of the 2nd International ISSX Meeting, KobeJapan, 1988, R. Kato, R. W. Estabrook, M. N. Cayen. Taylor & Francis, London, 245–253
   Google Scholar
• Ixagaki O., Shibasaki M., Takenaka T. Effect of YM09730–5 and standard calcium antagonists on blood pressure, heart rate and atrioventricular conduction after intravenous injection to conscious normotensive dogs. Clinical Report 1990; 24: 3833–3838, [in Japanese]
   Google Scholar
• Kleinbloesem C. H., Van Brummelen P., Faber H., Danhof M., Vermeulen N. P. E., Breimer D. D. Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man. Biochemical Pharmacology 1984; 33: 3721–3724
   PubMed Web of Science ®Google Scholar
• Kobayashi H., Kobayashi S., Inoue A., Oka T., Nakamizo N. Pharmacokinetic study of benidipine hydrochloride in rats and dogs. Arzneitmittel-Forsch 1988; 38: 1750–1753
   PubMed Web of Science ®Google Scholar
• Krause H. P., Ahr H. J., Beermann D., Siefert H. M., Suwelack D., Weber H. The pharmacokinetics of Nitrendipine, I. Absorption, plasma concentrations, and excretion after single administration of [14C] nitrendipine to rats and dogs. Arzneimittel-Forsch 1988; 38: 1593–1599
   PubMed Web of Science ®Google Scholar
• Raemsch K. D., Sommer J. Pharmacokinetics and metabolism of nitrendipine. Nitrendipine, A. Scriabine, S Varnov, K. Beck. Urbar & Schwarzenberz, Baltimore 1986; 406–421
   Google Scholar
• Rowland M., Tozer T. N. Concept and kinetics, Chapter 3. Clinical Pharmacokinetics: Concepts and Applications, 2nd Edition. Lea & Febiger, Philadelphia 1989; 132
   Google Scholar
• Stopher D. A., Beresford A. P., MaCrae P. V., Humphrey M. J. The metabolism and pharmacokinetics of amlodipine in humans and animals. Journal of Cardiovascular Pharmacology 1988; 12(suppl. 7)S55–59
   PubMed Web of Science ®Google Scholar
• Tamazawa K., Arima H., Kojima T., Isomura Y., Okada M., Fujita S., Furuya T., Takenaka T., Inagaki O., Terai M. Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl—4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Journal of Medicinal Chemistry 1986; 29: 2504–2511
   PubMed Web of Science ®Google Scholar
• Terakawa M., Tokuma Y., Shishido A., Noguchi H. Pharmacokinetics of nilvadipine in healthy volunteers. Journal of Clinical Pharmacology 1987; 27: 111–117
   PubMed Web of Science ®Google Scholar
• Teramura T., Kobayashi S., Higuchi S. Determination of mepirodipine in plasma by capillary column gas chromatography-negative-ion chemical ioniation mass spectrometry. Journal of Chromatography 1990; 528: 191–198
   PubMed Web of Science ®Google Scholar
• Teramuka T., Kobayashi S., Higuchi S. Metabolism of barnidipine hydrochloride in rats, dogs and humans. Abstract published in Proceedings of the 5th European International Society for the Study of Xenobiotics Meeting, ToursFrance, 1993, 103
   Google Scholar
• Tokuma Y., Sekiguchi M., Niwa T., Noguchi H. Pharmacokinetics of nilvadipine, a new dihydropyridine calcium antagonist, in mice, rats, rabbits and dogs. Xenobiotica 1988; 18: 21–28
   PubMed Web of Science ®Google Scholar
• Vinge E., Andersson K. E., Brandt L., Ljunggren B., Nilsson L. G., Helgesen S. R. Pharmocokinetics of nimodipine in patients with aneurysmal subarachnoid haemorrhage. European Journal of Clinical Pharmacology 1986; 30: 421–425
   PubMed Web of Science ®Google Scholar
• van Harten J., van Brummelen P., Danhoff M., Lodewijks M., Breimer D. D. Pharmacokinetics and haemodynamic effects of nisoldipine and its interaction with cimetidine in healthy volunteers. Acta Pharmacologica et Toxicologica 1986; 59(suppl. 5)180
   Google Scholar
• Walker D. K., Humphrey M. J., Smith D. A. Importance of metabolic stability and hepatic distribution to the pharmacokinetic profile of amlodipine. Xenobiotica 1994; 24: 243–250
   PubMed Web of Science ®Google Scholar
• Yamada S., Matsuoka Y., Kato Y., Kimura R., Inagaki O. A sustained occupancy in vivo of cardiovascular calcium antagonist receptors by mepirodipine and its relation to pharmacodynamic effect in spontaneously hypertensive rats. Journal of Pharmacology and Experimental Therapeutics 1992; 262: 589–594
   PubMed Web of Science ®Google Scholar